New rhodomycin analogs, SS-288A and SS-288B, produced by a Streptomyces violaceus A262 mutant

Biosci Biotechnol Biochem. 1995 Jan;59(1):135-7. doi: 10.1271/bbb.59.135.

Abstract

Two new rhodomycin metabolites, SS-288A and SS-288B, were specifically produced by a blocked mutant obtained from Streptomyces violaceus A262 and were respectively identified as 7,10-di(O-rhodosaminyl-deoxyfucosyl-deoxyfucosyl)-beta -rhodomycinone and -beta-isorhodomycinone.

MeSH terms

  • Anthracyclines
  • Antibiotics, Antineoplastic / blood*
  • Antibiotics, Antineoplastic / chemistry
  • Antibiotics, Antineoplastic / isolation & purification
  • Chromatography, Thin Layer
  • Magnetic Resonance Spectroscopy
  • Mutation / genetics
  • Streptomyces / genetics
  • Streptomyces / metabolism*

Substances

  • Anthracyclines
  • Antibiotics, Antineoplastic
  • SS 288A
  • SS 288B
  • rhodomycin