Familial breast cancer. BRCA1 down, BRCA2 to go

Curr Biol. 1994 Nov 1;4(11):1023-4. doi: 10.1016/s0960-9822(00)00232-3.

Abstract

The breast cancer susceptibility gene BRCA1 has been cloned and a second susceptibility gene, BRCA2, chromosomally mapped; will most breast and ovarian cancer turn out to be familial?

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / genetics*
  • Breast Neoplasms, Male / genetics
  • Chromosome Mapping
  • Chromosomes, Human, Pair 17
  • Cloning, Molecular
  • Female
  • Genes, Tumor Suppressor*
  • Genetic Linkage
  • Genetic Markers
  • Humans
  • Male
  • Mutation
  • Ovarian Neoplasms / genetics

Substances

  • Genetic Markers