Localization of the gene encoding human phosphatidylinositol transfer protein (PITPN) to 17p13.3: a gene showing homology to the Drosophila retinal degeneration B gene (rdgB)

Cytogenet Cell Genet. 1994;67(3):205-7. doi: 10.1159/000133823.

Abstract

The human gene for phosphatidylinositol transfer protein (PITPN) has previously been shown to share sequence and functional homology to part of the Drosophila retinal degeneration B gene (rdgB). In view of the possible involvement of the PITPN locus in the etiology of retinal disease, the gene has been mapped to human chromosome 17p13.3 and mouse Chromosome 11.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Carrier Proteins / genetics*
  • Chromosome Mapping
  • Chromosomes, Human, Pair 17*
  • Drosophila / genetics*
  • Humans
  • Membrane Proteins*
  • Mice
  • Molecular Sequence Data
  • Phospholipid Transfer Proteins
  • Polymorphism, Restriction Fragment Length
  • Retinal Degeneration / genetics*
  • Sequence Homology, Amino Acid*

Substances

  • Carrier Proteins
  • Membrane Proteins
  • Phospholipid Transfer Proteins