Plasmenylethanolamine in human intestinal mucosa detected by an improved method for analysis of phospholipid

Biochem Mol Biol Int. 1994 Jun;33(3):457-62.

Abstract

Analysis of phospholipid and their fatty acid composition of human intestinal mucosa was performed by an method elaborated to analyze the limited amount of sample with 2-dimensional TLC followed by lipid-phosphorus determination. Using this method, plasmenylethanolamine was detected in human intestinal mucosa and accounted for about 7% of phospholipid in small and large intestinal mucosa. The amounts of polyunsaturated fatty acids of phosphatidylethanolamine were higher than those of other phosphoglycerides in intestinal mucosa, hence, inflammation-related eicosanoids may originate from ethanolamine containing phospholipid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arachidonic Acid / analysis
  • Chromatography, Gas
  • Chromatography, Thin Layer / methods
  • Colon / chemistry
  • Fatty Acids / analysis
  • Humans
  • Intestinal Mucosa / chemistry*
  • Phospholipids / metabolism
  • Plasmalogens / analysis*
  • Sensitivity and Specificity

Substances

  • Fatty Acids
  • Phospholipids
  • Plasmalogens
  • phosphatidal ethanolamines
  • Arachidonic Acid