Intracerebral hemorrhage complicating urokinase infusion into an occluded aortocoronary bypass graft

M A Taylor; E C Santoian; J Aji; W J Eldredge; S D Cha; C A Dennis

doi:10.1002/ccd.1810310309

Intracerebral hemorrhage complicating urokinase infusion into an occluded aortocoronary bypass graft

Cathet Cardiovasc Diagn. 1994 Mar;31(3):206-10. doi: 10.1002/ccd.1810310309.

Authors

M A Taylor¹, E C Santoian, J Aji, W J Eldredge, S D Cha, C A Dennis

Affiliation

¹ Department of Cardiology, Deborah Heart and Lung Center, Browns Mills, New Jersey 08015.

PMID: 8025938
DOI: 10.1002/ccd.1810310309

Abstract

Selective infusion of urokinase into occluded coronary bypass vein grafts is effective in restoring patency. We report the occurrence of intracerebral hemorrhage complicating an intra-graft urokinase infusion protocol. The patient had known cerebral vascular structural pathology without recent clinical complications. Caution with the use of thrombolysis in this setting is suggested.

Publication types

Case Reports

MeSH terms

Cerebral Hemorrhage / chemically induced*
Contraindications
Coronary Artery Bypass*
Graft Occlusion, Vascular / drug therapy*
Humans
Infusions, Intravenous
Male
Middle Aged
Saphenous Vein / transplantation
Thrombolytic Therapy / adverse effects*
Time Factors
Urokinase-Type Plasminogen Activator / administration & dosage
Urokinase-Type Plasminogen Activator / adverse effects*
Urokinase-Type Plasminogen Activator / therapeutic use

Substances

Urokinase-Type Plasminogen Activator