Abstract
We describe a 30-year-old acute myelomonocytic leukemia patient with abnormal bone marrow eosinophils (AML FAB subtype M4Eo) with extensive extramedullary involvement and, in the abscence of an aberration involving chromosome 16, clonal trisomy 21 in the leukemic blast cells.
MeSH terms
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Adult
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Aminoglutethimide / therapeutic use
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bone Marrow / pathology*
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Danazol / therapeutic use
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Down Syndrome / complications*
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Eosinophils / pathology*
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Humans
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Leukemia, Myelomonocytic, Acute / drug therapy
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Leukemia, Myelomonocytic, Acute / genetics*
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Leukemia, Myelomonocytic, Acute / pathology*
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Male
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Tamoxifen / therapeutic use
Substances
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Tamoxifen
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Aminoglutethimide
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Danazol