Acute myocardial infarction complicating urokinase infusion for total saphenous vein graft occlusion

Cathet Cardiovasc Diagn. 1993 Jan;28(1):39-43. doi: 10.1002/ccd.1810280108.

Abstract

Saphenous vein graft occlusions have been successfully treated with extended urokinase infusions. We report a case of myocardial infarction complicating this treatment. A review of reported cases suggests that this complication may not be uncommon. The optional drug, dose, and infusion technique for intra-graft lytic therapy has not been determined. The costs, risks, and difficulty of this technique may limit its application.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angina, Unstable / etiology
  • Coronary Artery Bypass
  • Costs and Cost Analysis
  • Graft Occlusion, Vascular / complications
  • Graft Occlusion, Vascular / drug therapy*
  • Humans
  • Male
  • Myocardial Infarction / chemically induced*
  • Saphenous Vein / transplantation*
  • Thrombolytic Therapy / adverse effects*
  • Thrombolytic Therapy / methods
  • Urokinase-Type Plasminogen Activator / adverse effects*
  • Urokinase-Type Plasminogen Activator / therapeutic use

Substances

  • Urokinase-Type Plasminogen Activator