RNA splicing: unexpected spliceosome diversity

J P Kreivi; A I Lamond

doi:10.1016/s0960-9822(02)00599-7

RNA splicing: unexpected spliceosome diversity

Curr Biol. 1996 Jul 1;6(7):802-5. doi: 10.1016/s0960-9822(02)00599-7.

Authors

J P Kreivi¹, A I Lamond

Affiliation

¹ Department of Biochemistry, University of Dundee, Scotland, UK.

PMID: 8835860
DOI: 10.1016/s0960-9822(02)00599-7

Abstract

A novel form of spliceosome, containing the minor snRNPs U11 and U12, splices a class of pre-mRNA introns with non-consensus splice sites. This unexpected spliceosome diversity has interesting implications for the evolution and expression of eukaryotic genes.

Publication types

Review

MeSH terms

Animals
Humans
Introns*
Nuclear Proteins / genetics*
RNA Precursors*
RNA Splicing*
Ribonucleoproteins, Small Nuclear / metabolism*
Spliceosomes
tRNA Methyltransferases

Substances

Nuclear Proteins
RNA Precursors
Ribonucleoproteins, Small Nuclear
U11 small nuclear ribonucleoprotein, human
U11-U12 small nuclear ribonucleoprotein
NOP2 protein, human
tRNA Methyltransferases