Human heat shock protein gene polymorphisms and sudden infant death syndrome

Arch Dis Child. 1996 Nov;75(5):451-2. doi: 10.1136/adc.75.5.451.

Abstract

Comparison of the frequency of occurrence of restriction fragment length polymorphisms in control human DNAs and DNAs from infants dying from sudden infant death syndrome has indicated no significant difference in the case of restriction fragment length polymorphisms associated with the heat shock protein genes hsp70 and hsp90. A highly significant difference was detected, however, in the case of the specific restriction fragment length polymorphisms detected by an hsp60 gene probe in MspI digests.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chaperonin 60 / genetics
  • DNA / genetics
  • HSP70 Heat-Shock Proteins / genetics
  • HSP90 Heat-Shock Proteins / genetics
  • Heat-Shock Proteins / genetics*
  • Humans
  • Infant
  • Polymorphism, Restriction Fragment Length*
  • Sudden Infant Death / genetics*

Substances

  • Chaperonin 60
  • HSP70 Heat-Shock Proteins
  • HSP90 Heat-Shock Proteins
  • Heat-Shock Proteins
  • DNA