Abstract
We report a case of AML, acute myeloid leukaemia, with a novel translocation involving the short arms of chromosomes 9 and 17. The acute myeloid leukaemia was morphologically classified as FAB subtype M2. A prolonged remission was induced with chemotherapy, followed by a relapse which was associated with the finding of the same translocation.
MeSH terms
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Chromosomes, Human, Pair 17 / genetics
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Chromosomes, Human, Pair 17 / ultrastructure*
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Chromosomes, Human, Pair 9 / genetics
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Chromosomes, Human, Pair 9 / ultrastructure*
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Cyclophosphamide / administration & dosage
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Cytarabine / administration & dosage
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Daunorubicin / administration & dosage
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Genes, Tumor Suppressor
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Humans
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Leukemia, Myeloid, Acute / drug therapy
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Leukemia, Myeloid, Acute / genetics*
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Male
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Prednisone / administration & dosage
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Recurrence
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Remission Induction
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Salvage Therapy
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Thioguanine / administration & dosage
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Translocation, Genetic*
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Vincristine / administration & dosage
Substances
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Cytarabine
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Vincristine
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Cyclophosphamide
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Thioguanine
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Prednisone
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Daunorubicin