Objectives: To determine the relationship between human leukocyte antigen (HLA) loci and restenosis after percutaneous transluminal coronary angioplasty (PTCA).
Design and setting: Cross-sectional study in patients treated by PTCA at Juntendo University Hospital, Tokyo, Japan.
Patients: A total of 65 patients (58 males and 7 females) with coronary artery stenosis who were consecutively selected between October 1994 and June 1995.
Main outcome measures: Significant relationships between the restenosis and the HLA-Cw1.
Results: Among HLA-C locus, Cw1 was negatively related to restenosis (multivariate adjusted odds ratio, 0.19; 95% confidence interval, 0.06-0.63; P=.007).
Conclusions: In HLA typing, Cw1 may be a useful marker for the prediction of restenosis after PTCA.