Cystic fibrosis, Duchenne muscular dystrophy and preimplantation genetic diagnosis

J Liu; W Lissens; P Devroey; I Liebaers; A Van Steirteghem

doi:10.1093/humupd/2.6.531

Cystic fibrosis, Duchenne muscular dystrophy and preimplantation genetic diagnosis

Hum Reprod Update. 1996 Nov-Dec;2(6):531-9. doi: 10.1093/humupd/2.6.531.

Authors

J Liu¹, W Lissens, P Devroey, I Liebaers, A Van Steirteghem

Affiliation

¹ Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University, Belgium.

PMID: 9111186
DOI: 10.1093/humupd/2.6.531

Abstract

Cystic fibrosis (CF) is the most common genetic disease among Caucasians. Duchenne muscular dystrophy (DMD) is one of the most common X-linked genetic disorders. The CF and DMD genes were discovered a few years ago, which provided the possibility for prenatal diagnosis and preimplantation diagnosis of CF and DMD by using specific DNA analysis. In this article, CF, DMD, the process of the identification of the genes of CF and DMD and preimplantation genetic diagnosis are briefly described.

Publication types

Review

MeSH terms

Blastocyst*
Cystic Fibrosis / diagnosis*
Cystic Fibrosis / epidemiology
Cystic Fibrosis / genetics*
Cystic Fibrosis Transmembrane Conductance Regulator / genetics
Female
Genetic Carrier Screening
Humans
Male
Muscular Dystrophies / diagnosis*
Muscular Dystrophies / epidemiology
Muscular Dystrophies / genetics*
Pregnancy
Prenatal Diagnosis
Vas Deferens / abnormalities
White People / genetics
X Chromosome

Substances

CFTR protein, human
Cystic Fibrosis Transmembrane Conductance Regulator