Abstract
Boys are heavier than girls at term birth. Children with a 46,XY karyotype and androgen insensitivity syndrome (clinically complete form and/or proven mutations in the androgen receptor gene) were found to have a birth weight comparable to that of girls. These findings support the hypothesis that the difference in birth weight between boys and girls is generated by androgen action.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Androgen-Insensitivity Syndrome / genetics
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Androgen-Insensitivity Syndrome / physiopathology*
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Androgens / physiology*
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Birth Weight*
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Embryonic and Fetal Development*
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Female
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Humans
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Infant, Newborn
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Male
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Mutation
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Receptors, Androgen / genetics
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Sex Characteristics
Substances
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Androgens
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Receptors, Androgen