Metastatic RCC arising in a transplant kidney

Eur Radiol. 1998;8(8):1441-3. doi: 10.1007/s003300050570.

Abstract

We report a case of metastatic renal cell carcinoma arising in a cadaver transplant kidney 6 years after transplantation. Due to molecular analysis of the tumor tissue we could prove that the carcinoma originated from the male donor. After tumor resection and interruption of immunotherapy, the concomitant bone and lymph node metastases resolved with alpha-interferon and interleukin-2-based immunotherapy.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Carcinoma, Renal Cell / diagnosis
  • Carcinoma, Renal Cell / secondary*
  • Carcinoma, Renal Cell / therapy
  • DNA, Neoplasm / analysis
  • Female
  • Follow-Up Studies
  • Humans
  • Interferon-alpha / therapeutic use
  • Interleukin-2 / therapeutic use
  • Kidney Neoplasms / etiology*
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / therapy
  • Kidney Transplantation / adverse effects*
  • Kidney Transplantation / pathology
  • Lumbar Vertebrae
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • Radiography
  • Renal Dialysis
  • Sex Chromosomes / genetics
  • Spinal Neoplasms / diagnosis
  • Spinal Neoplasms / secondary*
  • Spinal Neoplasms / therapy
  • Tissue Donors

Substances

  • Antineoplastic Agents
  • DNA, Neoplasm
  • Interferon-alpha
  • Interleukin-2