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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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PYR [cytosol]
Stable Identifier
R-ALL-29398
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Pyruvate, pyruvic acid, 2-Oxopropanoate, 2-Oxopropanoic acid, Pyroracemic acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Drug ADME (Bos taurus)
Aspirin ADME (Bos taurus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Bos taurus)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Pyruvate metabolism (Bos taurus)
LDH tetramer oxidises LACT to PYR (Bos taurus)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Bos taurus)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Bos taurus)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Bos taurus)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Bos taurus)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Bos taurus)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Bos taurus)
PYR [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Alanine metabolism (Bos taurus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Bos taurus)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Bos taurus)
PYR [cytosol]
Glutamate and glutamine metabolism (Bos taurus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Bos taurus)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Bos taurus)
Phenylalanine metabolism (Bos taurus)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Bos taurus)
PYR [cytosol]
Serine biosynthesis (Bos taurus)
PXLP-K56-SRR dimer deaminates D-Ser (Bos taurus)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Bos taurus)
PYR [cytosol]
Tryptophan catabolism (Bos taurus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Bos taurus)
PYR [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Glycolysis (Bos taurus)
PKM dephosphorylates PEP to PYR (Bos taurus)
PYR [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Nicotinate metabolism (Bos taurus)
Nicotinamide salvaging (Bos taurus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Bos taurus)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
Sialic acid metabolism (Bos taurus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Bos taurus)
PYR [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Proton-coupled monocarboxylate transport (Bos taurus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Bos taurus)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Bos taurus)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Multifunctional anion exchangers (Bos taurus)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Bos taurus)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Bos taurus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Bos taurus)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Drug ADME (Caenorhabditis elegans)
Aspirin ADME (Caenorhabditis elegans)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
LDH tetramer oxidises LACT to PYR (Caenorhabditis elegans)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Caenorhabditis elegans)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Caenorhabditis elegans)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Caenorhabditis elegans)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Caenorhabditis elegans)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Caenorhabditis elegans)
PYR [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Alanine metabolism (Caenorhabditis elegans)
PXLP-K314-GPT transaminates L-Ala to form PYR (Caenorhabditis elegans)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Caenorhabditis elegans)
PYR [cytosol]
Glutamate and glutamine metabolism (Caenorhabditis elegans)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Caenorhabditis elegans)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Caenorhabditis elegans)
Phenylalanine metabolism (Caenorhabditis elegans)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Caenorhabditis elegans)
PYR [cytosol]
Serine biosynthesis (Caenorhabditis elegans)
PXLP-K56-SRR dimer deaminates D-Ser (Caenorhabditis elegans)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Caenorhabditis elegans)
PYR [cytosol]
Tryptophan catabolism (Caenorhabditis elegans)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Caenorhabditis elegans)
PYR [cytosol]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Glycolysis (Caenorhabditis elegans)
PKM dephosphorylates PEP to PYR (Caenorhabditis elegans)
PYR [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Nicotinate metabolism (Caenorhabditis elegans)
Nicotinamide salvaging (Caenorhabditis elegans)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Caenorhabditis elegans)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Proton-coupled monocarboxylate transport (Caenorhabditis elegans)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Caenorhabditis elegans)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Multifunctional anion exchangers (Caenorhabditis elegans)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Caenorhabditis elegans)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Caenorhabditis elegans)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Caenorhabditis elegans)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Drug ADME (Canis familiaris)
Aspirin ADME (Canis familiaris)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Canis familiaris)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
LDH tetramer oxidises LACT to PYR (Canis familiaris)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Canis familiaris)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Canis familiaris)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Canis familiaris)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Canis familiaris)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Canis familiaris)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Canis familiaris)
PYR [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Alanine metabolism (Canis familiaris)
PXLP-K314-GPT transaminates L-Ala to form PYR (Canis familiaris)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Canis familiaris)
PYR [cytosol]
Glutamate and glutamine metabolism (Canis familiaris)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Canis familiaris)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Canis familiaris)
Phenylalanine metabolism (Canis familiaris)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Canis familiaris)
PYR [cytosol]
Serine biosynthesis (Canis familiaris)
PXLP-K56-SRR dimer deaminates D-Ser (Canis familiaris)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Canis familiaris)
PYR [cytosol]
Tryptophan catabolism (Canis familiaris)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Canis familiaris)
PYR [cytosol]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Glycolysis (Canis familiaris)
PKM dephosphorylates PEP to PYR (Canis familiaris)
PYR [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Nicotinate metabolism (Canis familiaris)
Nicotinamide salvaging (Canis familiaris)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Canis familiaris)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
Synthesis of substrates in N-glycan biosythesis (Canis familiaris)
Sialic acid metabolism (Canis familiaris)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Canis familiaris)
PYR [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Proton-coupled monocarboxylate transport (Canis familiaris)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Canis familiaris)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Canis familiaris)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Multifunctional anion exchangers (Canis familiaris)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Canis familiaris)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Canis familiaris)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Canis familiaris)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Pyruvate metabolism (Danio rerio)
LDH tetramer oxidises LACT to PYR (Danio rerio)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Danio rerio)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Danio rerio)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Danio rerio)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Danio rerio)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Danio rerio)
PYR [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Alanine metabolism (Danio rerio)
PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Danio rerio)
PYR [cytosol]
Glutamate and glutamine metabolism (Danio rerio)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Danio rerio)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Danio rerio)
Phenylalanine metabolism (Danio rerio)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Danio rerio)
PYR [cytosol]
Tryptophan catabolism (Danio rerio)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Danio rerio)
PYR [cytosol]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Glycolysis (Danio rerio)
PKM dephosphorylates PEP to PYR (Danio rerio)
PYR [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Nicotinate metabolism (Danio rerio)
Nicotinamide salvaging (Danio rerio)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Danio rerio)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
Synthesis of substrates in N-glycan biosythesis (Danio rerio)
Sialic acid metabolism (Danio rerio)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Danio rerio)
PYR [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Proton-coupled monocarboxylate transport (Danio rerio)
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Danio rerio)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Multifunctional anion exchangers (Danio rerio)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Danio rerio)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Danio rerio)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Danio rerio)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism (Dictyostelium discoideum)
PKM dephosphorylates PEP to PYR (Dictyostelium discoideum)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Dictyostelium discoideum)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Dictyostelium discoideum)
PYR [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Alanine metabolism (Dictyostelium discoideum)
PXLP-K314-GPT transaminates L-Ala to form PYR (Dictyostelium discoideum)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Dictyostelium discoideum)
PYR [cytosol]
Glutamate and glutamine metabolism (Dictyostelium discoideum)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Dictyostelium discoideum)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Dictyostelium discoideum)
Phenylalanine metabolism (Dictyostelium discoideum)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Dictyostelium discoideum)
PYR [cytosol]
Serine biosynthesis (Dictyostelium discoideum)
PXLP-K56-SRR dimer deaminates D-Ser (Dictyostelium discoideum)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Dictyostelium discoideum)
PYR [cytosol]
Tryptophan catabolism (Dictyostelium discoideum)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Dictyostelium discoideum)
PYR [cytosol]
Metabolism of carbohydrates (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Glycolysis (Dictyostelium discoideum)
PKM dephosphorylates PEP to PYR (Dictyostelium discoideum)
PYR [cytosol]
Drug ADME (Drosophila melanogaster)
Aspirin ADME (Drosophila melanogaster)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Drosophila melanogaster)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
LDH tetramer oxidises LACT to PYR (Drosophila melanogaster)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Drosophila melanogaster)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Drosophila melanogaster)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Drosophila melanogaster)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Drosophila melanogaster)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Drosophila melanogaster)
PYR [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Alanine metabolism (Drosophila melanogaster)
PXLP-K314-GPT transaminates L-Ala to form PYR (Drosophila melanogaster)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Drosophila melanogaster)
PYR [cytosol]
Glutamate and glutamine metabolism (Drosophila melanogaster)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Drosophila melanogaster)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Drosophila melanogaster)
Phenylalanine metabolism (Drosophila melanogaster)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Drosophila melanogaster)
PYR [cytosol]
Tryptophan catabolism (Drosophila melanogaster)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)
PYR [cytosol]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Glycolysis (Drosophila melanogaster)
PKM dephosphorylates PEP to PYR (Drosophila melanogaster)
PYR [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Nicotinate metabolism (Drosophila melanogaster)
Nicotinamide salvaging (Drosophila melanogaster)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Drosophila melanogaster)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Proton-coupled monocarboxylate transport (Drosophila melanogaster)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Drosophila melanogaster)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Drosophila melanogaster)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Multifunctional anion exchangers (Drosophila melanogaster)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Drosophila melanogaster)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Drosophila melanogaster)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Drosophila melanogaster)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Drug ADME (Gallus gallus)
Aspirin ADME (Gallus gallus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Gallus gallus)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Gallus gallus)
Carbohydrate metabolism (Gallus gallus)
Glycolysis (Gallus gallus)
phosphoenolpyruvate + ADP => pyruvate + ATP (Gallus gallus)
PYR [cytosol]
Pyruvate metabolism (Gallus gallus)
lactate + NAD+ <=> pyruvate + NADH + H+ (Gallus gallus)
PYR [cytosol]
pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] (Gallus gallus)
PYR [cytosol]
pyruvate + NADH + H+ <=> lactate + NAD+ (Gallus gallus)
PYR [cytosol]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
Synthesis of substrates in N-glycan biosythesis (Gallus gallus)
Sialic acid metabolism (Gallus gallus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Gallus gallus)
PYR [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Proton-coupled monocarboxylate transport (Gallus gallus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Gallus gallus)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Gallus gallus)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Multifunctional anion exchangers (Gallus gallus)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Gallus gallus)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Gallus gallus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Gallus gallus)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Drug ADME (Homo sapiens)
Aspirin ADME (Homo sapiens)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
Cytosolic H2O2 decarboxylates PYR to acetate (Homo sapiens)
PYR [cytosol]
LDH tetramer oxidises LACT to PYR (Homo sapiens)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Homo sapiens)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Homo sapiens)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Homo sapiens)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Homo sapiens)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Homo sapiens)
PYR [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Alanine metabolism (Homo sapiens)
PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Homo sapiens)
PYR [cytosol]
Glutamate and glutamine metabolism (Homo sapiens)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Homo sapiens)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Homo sapiens)
Phenylalanine metabolism (Homo sapiens)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Homo sapiens)
PYR [cytosol]
Serine biosynthesis (Homo sapiens)
PXLP-K56-SRR dimer deaminates D-Ser (Homo sapiens)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Homo sapiens)
PYR [cytosol]
Tryptophan catabolism (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Homo sapiens)
PYR [cytosol]
kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] (Homo sapiens)
PYR [cytosol]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Glycolysis (Homo sapiens)
PKM dephosphorylates PEP to PYR (Homo sapiens)
PYR [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Nicotinate metabolism (Homo sapiens)
Nicotinamide salvaging (Homo sapiens)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Homo sapiens)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
Sialic acid metabolism (Homo sapiens)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Homo sapiens)
PYR [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Proton-coupled monocarboxylate transport (Homo sapiens)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Multifunctional anion exchangers (Homo sapiens)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Homo sapiens)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Homo sapiens)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Homo sapiens)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Drug ADME (Mus musculus)
Aspirin ADME (Mus musculus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Mus musculus)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
LDH tetramer oxidises LACT to PYR (Mus musculus)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Mus musculus)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Mus musculus)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Mus musculus)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Mus musculus)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Mus musculus)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Mus musculus)
PYR [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Alanine metabolism (Mus musculus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Mus musculus)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Mus musculus)
PYR [cytosol]
Glutamate and glutamine metabolism (Mus musculus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Mus musculus)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Mus musculus)
Phenylalanine metabolism (Mus musculus)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Mus musculus)
PYR [cytosol]
Serine biosynthesis (Mus musculus)
PXLP-K56-SRR dimer deaminates D-Ser (Mus musculus)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Mus musculus)
PYR [cytosol]
Tryptophan catabolism (Mus musculus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Mus musculus)
PYR [cytosol]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Glycolysis (Mus musculus)
PKM dephosphorylates PEP to PYR (Mus musculus)
PYR [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Nicotinate metabolism (Mus musculus)
Nicotinamide salvaging (Mus musculus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Mus musculus)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Mus musculus)
Synthesis of substrates in N-glycan biosythesis (Mus musculus)
Sialic acid metabolism (Mus musculus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Mus musculus)
PYR [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Proton-coupled monocarboxylate transport (Mus musculus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Mus musculus)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Mus musculus)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Mus musculus)
Multifunctional anion exchangers (Mus musculus)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Mus musculus)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Mus musculus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Mus musculus)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Pyruvate metabolism (Plasmodium falciparum)
PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Plasmodium falciparum)
PYR [cytosol]
Metabolism of carbohydrates (Plasmodium falciparum)
Glucose metabolism (Plasmodium falciparum)
Glycolysis (Plasmodium falciparum)
PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
PYR [cytosol]
Drug ADME (Rattus norvegicus)
Aspirin ADME (Rattus norvegicus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
LDH tetramer oxidises LACT to PYR (Rattus norvegicus)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Rattus norvegicus)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Rattus norvegicus)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Rattus norvegicus)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Rattus norvegicus)
PYR [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Alanine metabolism (Rattus norvegicus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Rattus norvegicus)
PYR [cytosol]
Glutamate and glutamine metabolism (Rattus norvegicus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Rattus norvegicus)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Rattus norvegicus)
Phenylalanine metabolism (Rattus norvegicus)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Rattus norvegicus)
PYR [cytosol]
Serine biosynthesis (Rattus norvegicus)
PXLP-K56-SRR dimer deaminates D-Ser (Rattus norvegicus)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Rattus norvegicus)
PYR [cytosol]
Tryptophan catabolism (Rattus norvegicus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Rattus norvegicus)
PYR [cytosol]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Glycolysis (Rattus norvegicus)
PKM dephosphorylates PEP to PYR (Rattus norvegicus)
PYR [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Nicotinate metabolism (Rattus norvegicus)
Nicotinamide salvaging (Rattus norvegicus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Rattus norvegicus)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Asparagine N-linked glycosylation (Rattus norvegicus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Rattus norvegicus)
Synthesis of substrates in N-glycan biosythesis (Rattus norvegicus)
Sialic acid metabolism (Rattus norvegicus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Rattus norvegicus)
PYR [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Proton-coupled monocarboxylate transport (Rattus norvegicus)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Multifunctional anion exchangers (Rattus norvegicus)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Rattus norvegicus)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Rattus norvegicus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Rattus norvegicus)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism (Saccharomyces cerevisiae)
PKM dephosphorylates PEP to PYR (Saccharomyces cerevisiae)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Saccharomyces cerevisiae)
PYR [cytosol]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Alanine metabolism (Saccharomyces cerevisiae)
PXLP-K314-GPT transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
PYR [cytosol]
Glutamate and glutamine metabolism (Saccharomyces cerevisiae)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Saccharomyces cerevisiae)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Saccharomyces cerevisiae)
Phenylalanine metabolism (Saccharomyces cerevisiae)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Saccharomyces cerevisiae)
PYR [cytosol]
Serine biosynthesis (Saccharomyces cerevisiae)
PXLP-K56-SRR dimer deaminates D-Ser (Saccharomyces cerevisiae)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Saccharomyces cerevisiae)
PYR [cytosol]
Tryptophan catabolism (Saccharomyces cerevisiae)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Saccharomyces cerevisiae)
PYR [cytosol]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Glycolysis (Saccharomyces cerevisiae)
PKM dephosphorylates PEP to PYR (Saccharomyces cerevisiae)
PYR [cytosol]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism (Schizosaccharomyces pombe)
PKM dephosphorylates PEP to PYR (Schizosaccharomyces pombe)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Schizosaccharomyces pombe)
PYR [cytosol]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Glutamate and glutamine metabolism (Schizosaccharomyces pombe)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Schizosaccharomyces pombe)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Schizosaccharomyces pombe)
Phenylalanine metabolism (Schizosaccharomyces pombe)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Schizosaccharomyces pombe)
PYR [cytosol]
Serine biosynthesis (Schizosaccharomyces pombe)
PXLP-K56-SRR dimer deaminates D-Ser (Schizosaccharomyces pombe)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Schizosaccharomyces pombe)
PYR [cytosol]
Tryptophan catabolism (Schizosaccharomyces pombe)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Schizosaccharomyces pombe)
PYR [cytosol]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Glycolysis (Schizosaccharomyces pombe)
PKM dephosphorylates PEP to PYR (Schizosaccharomyces pombe)
PYR [cytosol]
Drug ADME (Sus scrofa)
Aspirin ADME (Sus scrofa)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Sus scrofa)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
LDH tetramer oxidises LACT to PYR (Sus scrofa)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Sus scrofa)
PYR [cytosol]
ME1 tetramer decarboxylates MAL to PYR (Sus scrofa)
PYR [cytosol]
ME1 tetramer decarboxylates OA to PYR (Sus scrofa)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Sus scrofa)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Sus scrofa)
PYR [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Alanine metabolism (Sus scrofa)
PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Sus scrofa)
PYR [cytosol]
Glutamate and glutamine metabolism (Sus scrofa)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Sus scrofa)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Sus scrofa)
Phenylalanine metabolism (Sus scrofa)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Sus scrofa)
PYR [cytosol]
Serine biosynthesis (Sus scrofa)
PXLP-K56-SRR dimer deaminates D-Ser (Sus scrofa)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Sus scrofa)
PYR [cytosol]
Tryptophan catabolism (Sus scrofa)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Sus scrofa)
PYR [cytosol]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Glycolysis (Sus scrofa)
PKM dephosphorylates PEP to PYR (Sus scrofa)
PYR [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Nicotinate metabolism (Sus scrofa)
Nicotinamide salvaging (Sus scrofa)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Sus scrofa)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Sus scrofa)
Synthesis of substrates in N-glycan biosythesis (Sus scrofa)
Sialic acid metabolism (Sus scrofa)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Sus scrofa)
PYR [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Proton-coupled monocarboxylate transport (Sus scrofa)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Sus scrofa)
MCT substrates [cytosol]
PYR [cytosol]
SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Sus scrofa)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Sus scrofa)
Multifunctional anion exchangers (Sus scrofa)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Sus scrofa)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Sus scrofa)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Sus scrofa)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Drug ADME (Xenopus tropicalis)
Aspirin ADME (Xenopus tropicalis)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Xenopus tropicalis)
MCT substrates [cytosol]
PYR [cytosol]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
LDH tetramer oxidises LACT to PYR (Xenopus tropicalis)
PYR [cytosol]
LDH tetramer reduces PYR to LACT (Xenopus tropicalis)
PYR [cytosol]
PKM dephosphorylates PEP to PYR (Xenopus tropicalis)
PYR [cytosol]
PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)
PYR [cytosol]
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Xenopus tropicalis)
PYR [cytosol]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Alanine metabolism (Xenopus tropicalis)
PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)
PYR [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Xenopus tropicalis)
PYR [cytosol]
Glutamate and glutamine metabolism (Xenopus tropicalis)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Xenopus tropicalis)
PYR [cytosol]
Phenylalanine and tyrosine metabolism (Xenopus tropicalis)
Phenylalanine metabolism (Xenopus tropicalis)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Xenopus tropicalis)
PYR [cytosol]
Serine biosynthesis (Xenopus tropicalis)
PXLP-K56-SRR dimer deaminates D-Ser (Xenopus tropicalis)
PYR [cytosol]
PXLP-K56-SRR dimer deaminates L-Ser (Xenopus tropicalis)
PYR [cytosol]
Tryptophan catabolism (Xenopus tropicalis)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Xenopus tropicalis)
PYR [cytosol]
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Glycolysis (Xenopus tropicalis)
PKM dephosphorylates PEP to PYR (Xenopus tropicalis)
PYR [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Nicotinate metabolism (Xenopus tropicalis)
Nicotinamide salvaging (Xenopus tropicalis)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Xenopus tropicalis)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Asparagine N-linked glycosylation (Xenopus tropicalis)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Xenopus tropicalis)
Synthesis of substrates in N-glycan biosythesis (Xenopus tropicalis)
Sialic acid metabolism (Xenopus tropicalis)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Xenopus tropicalis)
PYR [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Proton-coupled monocarboxylate transport (Xenopus tropicalis)
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Xenopus tropicalis)
MCT substrates [cytosol]
PYR [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Xenopus tropicalis)
Multifunctional anion exchangers (Xenopus tropicalis)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Xenopus tropicalis)
LACT, PYR, NCA [cytosol]
PYR [cytosol]
Organic anion transporters (Xenopus tropicalis)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Xenopus tropicalis)
monocarboxylates transported by SLC5A8 [cytosol]
PYR [cytosol]
External Reference Information
External Reference
pyruvate [ChEBI:15361]
Participates
as an input of
pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] (Gallus gallus)
pyruvate + NADH + H+ <=> lactate + NAD+ (Gallus gallus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Saccharomyces cerevisiae)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Schizosaccharomyces pombe)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Dictyostelium discoideum)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Caenorhabditis elegans)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Drosophila melanogaster)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Gallus gallus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Xenopus tropicalis)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Danio rerio)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Sus scrofa)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Bos taurus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Canis familiaris)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Rattus norvegicus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Mus musculus)
glutamine + pyruvate => 2-oxoglutaramate + alanine (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Saccharomyces cerevisiae)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Schizosaccharomyces pombe)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Dictyostelium discoideum)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Caenorhabditis elegans)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Gallus gallus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Xenopus tropicalis)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Danio rerio)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Sus scrofa)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Bos taurus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Canis familiaris)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Rattus norvegicus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Mus musculus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Homo sapiens)
kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] (Homo sapiens)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Saccharomyces cerevisiae)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Schizosaccharomyces pombe)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Dictyostelium discoideum)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Caenorhabditis elegans)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Drosophila melanogaster)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Gallus gallus)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Xenopus tropicalis)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Danio rerio)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Sus scrofa)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Bos taurus)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Rattus norvegicus)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Mus musculus)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Homo sapiens)
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Canis familiaris)
Cytosolic H2O2 decarboxylates PYR to acetate (Homo sapiens)
Cytosolic PYR is transported to the mitochondrial matrix (Rattus norvegicus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Plasmodium falciparum)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Saccharomyces cerevisiae)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Schizosaccharomyces pombe)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Dictyostelium discoideum)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Caenorhabditis elegans)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Drosophila melanogaster)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Gallus gallus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Xenopus tropicalis)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Danio rerio)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Sus scrofa)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Bos taurus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Canis familiaris)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Rattus norvegicus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Mus musculus)
VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Homo sapiens)
LDH tetramer reduces PYR to LACT (Caenorhabditis elegans)
LDH tetramer reduces PYR to LACT (Drosophila melanogaster)
LDH tetramer reduces PYR to LACT (Gallus gallus)
LDH tetramer reduces PYR to LACT (Xenopus tropicalis)
LDH tetramer reduces PYR to LACT (Danio rerio)
LDH tetramer reduces PYR to LACT (Sus scrofa)
LDH tetramer reduces PYR to LACT (Bos taurus)
LDH tetramer reduces PYR to LACT (Canis familiaris)
LDH tetramer reduces PYR to LACT (Rattus norvegicus)
LDH tetramer reduces PYR to LACT (Mus musculus)
PXLP-K314-GPT transaminates PYR to form L-Ala (Homo sapiens)
PXLP-K314-GPT transaminates PYR to form L-Ala (Mus musculus)
PXLP-K314-GPT transaminates PYR to form L-Ala (Rattus norvegicus)
PXLP-K314-GPT transaminates PYR to form L-Ala (Canis familiaris)
PXLP-K314-GPT transaminates PYR to form L-Ala (Bos taurus)
PXLP-K314-GPT transaminates PYR to form L-Ala (Sus scrofa)
PXLP-K314-GPT transaminates PYR to form L-Ala (Danio rerio)
PXLP-K314-GPT transaminates PYR to form L-Ala (Xenopus tropicalis)
PXLP-K314-GPT transaminates PYR to form L-Ala (Drosophila melanogaster)
PXLP-K314-GPT transaminates PYR to form L-Ala (Caenorhabditis elegans)
PXLP-K314-GPT transaminates PYR to form L-Ala (Dictyostelium discoideum)
PXLP-K314-GPT transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
LDH tetramer reduces PYR to LACT (Homo sapiens)
as an output of
lactate + NAD+ <=> pyruvate + NADH + H+ (Gallus gallus)
phosphoenolpyruvate + ADP => pyruvate + ATP (Gallus gallus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Gallus gallus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Xenopus tropicalis)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Danio rerio)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Sus scrofa)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Bos taurus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Canis familiaris)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Rattus norvegicus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Mus musculus)
NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Homo sapiens)
ME1 tetramer decarboxylates OA to PYR (Caenorhabditis elegans)
ME1 tetramer decarboxylates OA to PYR (Drosophila melanogaster)
ME1 tetramer decarboxylates OA to PYR (Gallus gallus)
ME1 tetramer decarboxylates OA to PYR (Danio rerio)
ME1 tetramer decarboxylates OA to PYR (Sus scrofa)
ME1 tetramer decarboxylates OA to PYR (Bos taurus)
ME1 tetramer decarboxylates OA to PYR (Canis familiaris)
ME1 tetramer decarboxylates OA to PYR (Rattus norvegicus)
ME1 tetramer decarboxylates OA to PYR (Mus musculus)
ME1 tetramer decarboxylates OA to PYR (Homo sapiens)
PXLP-K56-SRR dimer deaminates L-Ser (Saccharomyces cerevisiae)
PXLP-K56-SRR dimer deaminates L-Ser (Schizosaccharomyces pombe)
PXLP-K56-SRR dimer deaminates L-Ser (Dictyostelium discoideum)
PXLP-K56-SRR dimer deaminates L-Ser (Caenorhabditis elegans)
PXLP-K56-SRR dimer deaminates L-Ser (Gallus gallus)
PXLP-K56-SRR dimer deaminates L-Ser (Xenopus tropicalis)
PXLP-K56-SRR dimer deaminates L-Ser (Sus scrofa)
PXLP-K56-SRR dimer deaminates L-Ser (Bos taurus)
PXLP-K56-SRR dimer deaminates L-Ser (Canis familiaris)
PXLP-K56-SRR dimer deaminates L-Ser (Rattus norvegicus)
PXLP-K56-SRR dimer deaminates L-Ser (Homo sapiens)
PXLP-K56-SRR dimer deaminates L-Ser (Mus musculus)
PXLP-K56-SRR dimer deaminates D-Ser (Saccharomyces cerevisiae)
PXLP-K56-SRR dimer deaminates D-Ser (Schizosaccharomyces pombe)
PXLP-K56-SRR dimer deaminates D-Ser (Dictyostelium discoideum)
PXLP-K56-SRR dimer deaminates D-Ser (Caenorhabditis elegans)
PXLP-K56-SRR dimer deaminates D-Ser (Gallus gallus)
PXLP-K56-SRR dimer deaminates D-Ser (Xenopus tropicalis)
PXLP-K56-SRR dimer deaminates D-Ser (Sus scrofa)
PXLP-K56-SRR dimer deaminates D-Ser (Bos taurus)
PXLP-K56-SRR dimer deaminates D-Ser (Canis familiaris)
PXLP-K56-SRR dimer deaminates D-Ser (Rattus norvegicus)
PXLP-K56-SRR dimer deaminates D-Ser (Homo sapiens)
PXLP-K56-SRR dimer deaminates D-Ser (Mus musculus)
LDH tetramer oxidises LACT to PYR (Caenorhabditis elegans)
LDH tetramer oxidises LACT to PYR (Drosophila melanogaster)
LDH tetramer oxidises LACT to PYR (Gallus gallus)
LDH tetramer oxidises LACT to PYR (Xenopus tropicalis)
LDH tetramer oxidises LACT to PYR (Danio rerio)
LDH tetramer oxidises LACT to PYR (Sus scrofa)
LDH tetramer oxidises LACT to PYR (Bos taurus)
LDH tetramer oxidises LACT to PYR (Canis familiaris)
LDH tetramer oxidises LACT to PYR (Rattus norvegicus)
LDH tetramer oxidises LACT to PYR (Mus musculus)
LDH tetramer oxidises LACT to PYR (Homo sapiens)
ME1 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
ME1 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
ME1 tetramer decarboxylates MAL to PYR (Gallus gallus)
ME1 tetramer decarboxylates MAL to PYR (Danio rerio)
PKM dephosphorylates PEP to PYR (Homo sapiens)
PKM dephosphorylates PEP to PYR (Mus musculus)
PKM dephosphorylates PEP to PYR (Rattus norvegicus)
PKM dephosphorylates PEP to PYR (Canis familiaris)
PKM dephosphorylates PEP to PYR (Bos taurus)
PKM dephosphorylates PEP to PYR (Sus scrofa)
PKM dephosphorylates PEP to PYR (Danio rerio)
PKM dephosphorylates PEP to PYR (Xenopus tropicalis)
PKM dephosphorylates PEP to PYR (Gallus gallus)
PKM dephosphorylates PEP to PYR (Drosophila melanogaster)
PKM dephosphorylates PEP to PYR (Caenorhabditis elegans)
PKM dephosphorylates PEP to PYR (Dictyostelium discoideum)
PKM dephosphorylates PEP to PYR (Schizosaccharomyces pombe)
PKM dephosphorylates PEP to PYR (Saccharomyces cerevisiae)
PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)
PXLP-K314-GPT transaminates L-Ala to form PYR (Mus musculus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Canis familiaris)
PXLP-K314-GPT transaminates L-Ala to form PYR (Bos taurus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)
PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)
PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)
PXLP-K314-GPT transaminates L-Ala to form PYR (Drosophila melanogaster)
PXLP-K314-GPT transaminates L-Ala to form PYR (Caenorhabditis elegans)
PXLP-K314-GPT transaminates L-Ala to form PYR (Dictyostelium discoideum)
PXLP-K314-GPT transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
ME1 tetramer decarboxylates MAL to PYR (Homo sapiens)
ME1 tetramer decarboxylates MAL to PYR (Mus musculus)
ME1 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
ME1 tetramer decarboxylates MAL to PYR (Canis familiaris)
ME1 tetramer decarboxylates MAL to PYR (Bos taurus)
ME1 tetramer decarboxylates MAL to PYR (Sus scrofa)
as a member of
MCT substrates [cytosol]
LACT, PYR, NCA [cytosol]
monocarboxylates transported by SLC5A8 [cytosol]
Other forms of this molecule
PYR [cytoplasm]
pyruvic acid [cytosol]
PYR [peroxisomal matrix]
PYR [extracellular region]
PYR [mitochondrial intermembrane space]
PYR [mitochondrial matrix]
Cross References
KNApSAcK
C00001200
AraCyc
PYRUVATE
CAS
127-17-3
COMPOUND
C00022
PubChem Compound
107735
UMBBD
c0159
ZINC
000001532517
KEGG Gene
C00022
,
c00022
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![PYR [cytosol] icon](/icon/R-ICO-013265.svg){kind=icon}
