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bHIBA [mitochondrial matrix]
Stable Identifier
R-ALL-573404
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
3-hydroxy-2-isobutyrate, 3-hydroxyisobutyrate, beta-hydroxyisobutyrate, 3-hydroxy-2-methylpropanoate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Branched-chain amino acid catabolism (Bos taurus)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Bos taurus)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Bos taurus)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Bos taurus)
bHIBA [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Branched-chain amino acid catabolism (Caenorhabditis elegans)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Caenorhabditis elegans)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Caenorhabditis elegans)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Caenorhabditis elegans)
bHIBA [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Branched-chain amino acid catabolism (Canis familiaris)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Canis familiaris)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Canis familiaris)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Canis familiaris)
bHIBA [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Branched-chain amino acid catabolism (Danio rerio)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Danio rerio)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Danio rerio)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Danio rerio)
bHIBA [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Branched-chain amino acid catabolism (Dictyostelium discoideum)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Dictyostelium discoideum)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Dictyostelium discoideum)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Dictyostelium discoideum)
bHIBA [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Branched-chain amino acid catabolism (Drosophila melanogaster)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Drosophila melanogaster)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Drosophila melanogaster)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Drosophila melanogaster)
bHIBA [mitochondrial matrix]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Branched-chain amino acid catabolism (Gallus gallus)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Gallus gallus)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Gallus gallus)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Gallus gallus)
bHIBA [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Branched-chain amino acid catabolism (Homo sapiens)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Homo sapiens)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Homo sapiens)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Homo sapiens)
bHIBA [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Branched-chain amino acid catabolism (Mus musculus)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Mus musculus)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Mus musculus)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Mus musculus)
bHIBA [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Branched-chain amino acid catabolism (Plasmodium falciparum)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Plasmodium falciparum)
bHIBA [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Branched-chain amino acid catabolism (Rattus norvegicus)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Rattus norvegicus)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Rattus norvegicus)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Rattus norvegicus)
bHIBA [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Branched-chain amino acid catabolism (Saccharomyces cerevisiae)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Saccharomyces cerevisiae)
bHIBA [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Branched-chain amino acid catabolism (Schizosaccharomyces pombe)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Schizosaccharomyces pombe)
bHIBA [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Branched-chain amino acid catabolism (Sus scrofa)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Sus scrofa)
bHIBA [mitochondrial matrix]
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Sus scrofa)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Sus scrofa)
bHIBA [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Branched-chain amino acid catabolism (Xenopus tropicalis)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Xenopus tropicalis)
bHIBA [mitochondrial matrix]
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Xenopus tropicalis)
bHIBA [mitochondrial matrix]
External Reference Information
External Reference
3-hydroxyisobutyrate [ChEBI:11805]
Participates
as an input of
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Dictyostelium discoideum)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Caenorhabditis elegans)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Drosophila melanogaster)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Gallus gallus)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Xenopus tropicalis)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Danio rerio)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Sus scrofa)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Bos taurus)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Canis familiaris)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Rattus norvegicus)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Homo sapiens)
beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Mus musculus)
as an output of
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Dictyostelium discoideum)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Caenorhabditis elegans)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Drosophila melanogaster)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Gallus gallus)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Xenopus tropicalis)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Danio rerio)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Sus scrofa)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Bos taurus)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Canis familiaris)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Rattus norvegicus)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Mus musculus)
methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Homo sapiens)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Plasmodium falciparum)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Saccharomyces cerevisiae)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Schizosaccharomyces pombe)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Dictyostelium discoideum)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Caenorhabditis elegans)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Drosophila melanogaster)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Gallus gallus)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Danio rerio)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Sus scrofa)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Bos taurus)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Canis familiaris)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Rattus norvegicus)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Homo sapiens)
beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Mus musculus)
Cross References
ZINC
000000895526
,
000000895528
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