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DHF [cytosol]
Stable Identifier
R-ALL-73604
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Dihydrofolate, dihydrofolic acid, 7,8-Dihydrofolate, 7,8-Dihydrofolic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Bos taurus)
DHF [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Metabolism of folate and pterines (Bos taurus)
DHF is reduced to tetrahydrofolate (THF) (Bos taurus)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Bos taurus)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Bos taurus)
DHF [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Caenorhabditis elegans)
DHF [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Metabolism of folate and pterines (Caenorhabditis elegans)
DHF is reduced to tetrahydrofolate (THF) (Caenorhabditis elegans)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Caenorhabditis elegans)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Caenorhabditis elegans)
DHF [cytosol]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Interconversion of nucleotide di- and triphosphates (Canis familiaris)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Canis familiaris)
DHF [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Metabolism of folate and pterines (Canis familiaris)
DHF is reduced to tetrahydrofolate (THF) (Canis familiaris)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Canis familiaris)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Canis familiaris)
DHF [cytosol]
Metabolism (Danio rerio)
Metabolism of nucleotides (Danio rerio)
Interconversion of nucleotide di- and triphosphates (Danio rerio)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Danio rerio)
DHF [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Metabolism of folate and pterines (Danio rerio)
DHF is reduced to tetrahydrofolate (THF) (Danio rerio)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Danio rerio)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Danio rerio)
DHF [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Metabolism of folate and pterines (Dictyostelium discoideum)
DHF is reduced to tetrahydrofolate (THF) (Dictyostelium discoideum)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Dictyostelium discoideum)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Dictyostelium discoideum)
DHF [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of nucleotides (Drosophila melanogaster)
Interconversion of nucleotide di- and triphosphates (Drosophila melanogaster)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Drosophila melanogaster)
DHF [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Metabolism of folate and pterines (Drosophila melanogaster)
DHF is reduced to tetrahydrofolate (THF) (Drosophila melanogaster)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Drosophila melanogaster)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Drosophila melanogaster)
DHF [cytosol]
Metabolism (Gallus gallus)
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Metabolism of folate and pterines (Gallus gallus)
DHF is reduced to tetrahydrofolate (THF) (Gallus gallus)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Gallus gallus)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Gallus gallus)
DHF [cytosol]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Homo sapiens)
DHF [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Metabolism of folate and pterines (Homo sapiens)
DHF is reduced to tetrahydrofolate (THF) (Homo sapiens)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Homo sapiens)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Homo sapiens)
DHF [cytosol]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Interconversion of nucleotide di- and triphosphates (Mus musculus)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Mus musculus)
DHF [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Metabolism of folate and pterines (Mus musculus)
DHF is reduced to tetrahydrofolate (THF) (Mus musculus)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Mus musculus)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Mus musculus)
DHF [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Interconversion of nucleotide di- and triphosphates (Plasmodium falciparum)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Plasmodium falciparum)
DHF [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Interconversion of nucleotide di- and triphosphates (Rattus norvegicus)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Rattus norvegicus)
DHF [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Metabolism of folate and pterines (Rattus norvegicus)
DHF is reduced to tetrahydrofolate (THF) (Rattus norvegicus)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Rattus norvegicus)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Rattus norvegicus)
DHF [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Interconversion of nucleotide di- and triphosphates (Saccharomyces cerevisiae)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Saccharomyces cerevisiae)
DHF [cytosol]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of folate and pterines (Saccharomyces cerevisiae)
DHF is reduced to tetrahydrofolate (THF) (Saccharomyces cerevisiae)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Saccharomyces cerevisiae)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Saccharomyces cerevisiae)
DHF [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Interconversion of nucleotide di- and triphosphates (Schizosaccharomyces pombe)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Schizosaccharomyces pombe)
DHF [cytosol]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of folate and pterines (Schizosaccharomyces pombe)
DHF is reduced to tetrahydrofolate (THF) (Schizosaccharomyces pombe)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Schizosaccharomyces pombe)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Schizosaccharomyces pombe)
DHF [cytosol]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Interconversion of nucleotide di- and triphosphates (Sus scrofa)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Sus scrofa)
DHF [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Metabolism of folate and pterines (Sus scrofa)
DHF is reduced to tetrahydrofolate (THF) (Sus scrofa)
DHF [cytosol]
DHFR dimer reduces FOLA to DHF (Sus scrofa)
DHF [cytosol]
DHFR2 reduces FOLA to DHF (Sus scrofa)
DHF [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Interconversion of nucleotide di- and triphosphates (Xenopus tropicalis)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Xenopus tropicalis)
DHF [cytosol]
External Reference Information
External Reference
dihydrofolate(2-) [ChEBI:57451]
Participates
as an input of
DHF is reduced to tetrahydrofolate (THF) (Homo sapiens)
DHF is reduced to tetrahydrofolate (THF) (Mus musculus)
DHF is reduced to tetrahydrofolate (THF) (Rattus norvegicus)
DHF is reduced to tetrahydrofolate (THF) (Canis familiaris)
DHF is reduced to tetrahydrofolate (THF) (Bos taurus)
DHF is reduced to tetrahydrofolate (THF) (Sus scrofa)
DHF is reduced to tetrahydrofolate (THF) (Danio rerio)
DHF is reduced to tetrahydrofolate (THF) (Gallus gallus)
DHF is reduced to tetrahydrofolate (THF) (Drosophila melanogaster)
DHF is reduced to tetrahydrofolate (THF) (Caenorhabditis elegans)
DHF is reduced to tetrahydrofolate (THF) (Dictyostelium discoideum)
DHF is reduced to tetrahydrofolate (THF) (Schizosaccharomyces pombe)
DHF is reduced to tetrahydrofolate (THF) (Saccharomyces cerevisiae)
as an output of
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Plasmodium falciparum)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Saccharomyces cerevisiae)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Schizosaccharomyces pombe)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Caenorhabditis elegans)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Drosophila melanogaster)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Xenopus tropicalis)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Danio rerio)
DHFR2 reduces FOLA to DHF (Homo sapiens)
DHFR2 reduces FOLA to DHF (Mus musculus)
DHFR2 reduces FOLA to DHF (Rattus norvegicus)
DHFR2 reduces FOLA to DHF (Canis familiaris)
DHFR2 reduces FOLA to DHF (Bos taurus)
DHFR2 reduces FOLA to DHF (Sus scrofa)
DHFR2 reduces FOLA to DHF (Danio rerio)
DHFR2 reduces FOLA to DHF (Gallus gallus)
DHFR2 reduces FOLA to DHF (Drosophila melanogaster)
DHFR2 reduces FOLA to DHF (Caenorhabditis elegans)
DHFR2 reduces FOLA to DHF (Dictyostelium discoideum)
DHFR2 reduces FOLA to DHF (Schizosaccharomyces pombe)
DHFR2 reduces FOLA to DHF (Saccharomyces cerevisiae)
DHFR dimer reduces FOLA to DHF (Homo sapiens)
DHFR dimer reduces FOLA to DHF (Mus musculus)
DHFR dimer reduces FOLA to DHF (Rattus norvegicus)
DHFR dimer reduces FOLA to DHF (Canis familiaris)
DHFR dimer reduces FOLA to DHF (Bos taurus)
DHFR dimer reduces FOLA to DHF (Sus scrofa)
DHFR dimer reduces FOLA to DHF (Danio rerio)
DHFR dimer reduces FOLA to DHF (Gallus gallus)
DHFR dimer reduces FOLA to DHF (Drosophila melanogaster)
DHFR dimer reduces FOLA to DHF (Caenorhabditis elegans)
DHFR dimer reduces FOLA to DHF (Dictyostelium discoideum)
DHFR dimer reduces FOLA to DHF (Schizosaccharomyces pombe)
DHFR dimer reduces FOLA to DHF (Saccharomyces cerevisiae)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Homo sapiens)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Mus musculus)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Rattus norvegicus)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Canis familiaris)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Bos taurus)
dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Sus scrofa)
Cross References
COMPOUND
C00415
ZINC
000004228265
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