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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
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Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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CIT [cytosol]
Stable Identifier
R-ALL-76190
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Citrate, citric acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Glycolysis (Bos taurus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Bos taurus)
CIT [cytosol]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Carnitine metabolism (Bos taurus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Bos taurus)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Bos taurus)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Bos taurus)
ACLY tetramer transforms CIT to Ac-CoA (Bos taurus)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Bos taurus)
CIT [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
NADPH regeneration (Bos taurus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Bos taurus)
CIT [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Bos taurus)
NACT co-transports trivalent citrate and a sodium ion (Bos taurus)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Bos taurus)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Organic anion transporters (Bos taurus)
SLC25A1 exchanges CIT and MAL (Bos taurus)
CIT [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Glycolysis (Caenorhabditis elegans)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Caenorhabditis elegans)
CIT [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Carnitine metabolism (Caenorhabditis elegans)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Caenorhabditis elegans)
ACLY tetramer transforms CIT to Ac-CoA (Caenorhabditis elegans)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Caenorhabditis elegans)
CIT [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of cofactors (Caenorhabditis elegans)
NADPH regeneration (Caenorhabditis elegans)
ACO1:4Fe-4S isomerises CIT to ISCIT (Caenorhabditis elegans)
CIT [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Caenorhabditis elegans)
NACT co-transports trivalent citrate and a sodium ion (Caenorhabditis elegans)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Caenorhabditis elegans)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Organic anion transporters (Caenorhabditis elegans)
SLC25A1 exchanges CIT and MAL (Caenorhabditis elegans)
CIT [cytosol]
Metabolism (Canis familiaris)
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Glycolysis (Canis familiaris)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Canis familiaris)
CIT [cytosol]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Carnitine metabolism (Canis familiaris)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Canis familiaris)
ACLY tetramer transforms CIT to Ac-CoA (Canis familiaris)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Canis familiaris)
CIT [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of cofactors (Canis familiaris)
NADPH regeneration (Canis familiaris)
ACO1:4Fe-4S isomerises CIT to ISCIT (Canis familiaris)
CIT [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Canis familiaris)
NACT co-transports trivalent citrate and a sodium ion (Canis familiaris)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Canis familiaris)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Organic anion transporters (Canis familiaris)
SLC25A1 exchanges CIT and MAL (Canis familiaris)
CIT [cytosol]
Metabolism (Danio rerio)
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Glycolysis (Danio rerio)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Danio rerio)
CIT [cytosol]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Fatty acyl-CoA biosynthesis (Danio rerio)
ACLY tetramer transforms CIT to Ac-CoA (Danio rerio)
CIT [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of cofactors (Danio rerio)
NADPH regeneration (Danio rerio)
ACO1:4Fe-4S isomerises CIT to ISCIT (Danio rerio)
CIT [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Danio rerio)
NaDC1 co-transports dicarboxylic acids and a sodium ion (Danio rerio)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Organic anion transporters (Danio rerio)
SLC25A1 exchanges CIT and MAL (Danio rerio)
CIT [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Carnitine metabolism (Dictyostelium discoideum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Dictyostelium discoideum)
ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Dictyostelium discoideum)
CIT [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of cofactors (Dictyostelium discoideum)
NADPH regeneration (Dictyostelium discoideum)
ACO1:4Fe-4S isomerises CIT to ISCIT (Dictyostelium discoideum)
CIT [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Glycolysis (Drosophila melanogaster)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Drosophila melanogaster)
CIT [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Carnitine metabolism (Drosophila melanogaster)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Drosophila melanogaster)
ACLY tetramer transforms CIT to Ac-CoA (Drosophila melanogaster)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Drosophila melanogaster)
CIT [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of cofactors (Drosophila melanogaster)
NADPH regeneration (Drosophila melanogaster)
ACO1:4Fe-4S isomerises CIT to ISCIT (Drosophila melanogaster)
CIT [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Drosophila melanogaster)
NACT co-transports trivalent citrate and a sodium ion (Drosophila melanogaster)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Drosophila melanogaster)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Organic anion transporters (Drosophila melanogaster)
SLC25A1 exchanges CIT and MAL (Drosophila melanogaster)
CIT [cytosol]
Metabolism (Gallus gallus)
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] (Gallus gallus)
CIT [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Gallus gallus)
NACT co-transports trivalent citrate and a sodium ion (Gallus gallus)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Gallus gallus)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Organic anion transporters (Gallus gallus)
SLC25A1 exchanges CIT and MAL (Gallus gallus)
CIT [cytosol]
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Glycolysis (Homo sapiens)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Homo sapiens)
CIT [cytosol]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Carnitine metabolism (Homo sapiens)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Homo sapiens)
ACLY tetramer transforms CIT to Ac-CoA (Homo sapiens)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Homo sapiens)
CIT [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
NADPH regeneration (Homo sapiens)
ACO1:4Fe-4S isomerises CIT to ISCIT (Homo sapiens)
CIT [cytosol]
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sour taste (Homo sapiens)
Protonated weak acid translocates across the plasma membrane (Homo sapiens)
weak acid [cytosol]
CIT [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Homo sapiens)
NACT co-transports trivalent citrate and a sodium ion (Homo sapiens)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Homo sapiens)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Organic anion transporters (Homo sapiens)
SLC25A1 exchanges CIT and MAL (Homo sapiens)
CIT [cytosol]
Metabolism (Mus musculus)
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Glycolysis (Mus musculus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Mus musculus)
CIT [cytosol]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Carnitine metabolism (Mus musculus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Mus musculus)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Mus musculus)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Mus musculus)
ACLY tetramer transforms CIT to Ac-CoA (Mus musculus)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Mus musculus)
CIT [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of cofactors (Mus musculus)
NADPH regeneration (Mus musculus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Mus musculus)
CIT [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Mus musculus)
NACT co-transports trivalent citrate and a sodium ion (Mus musculus)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Mus musculus)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Mus musculus)
Organic anion transporters (Mus musculus)
SLC25A1 exchanges CIT and MAL (Mus musculus)
CIT [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of lipids (Plasmodium falciparum)
Fatty acid metabolism (Plasmodium falciparum)
Carnitine metabolism (Plasmodium falciparum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Plasmodium falciparum)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Plasmodium falciparum)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Plasmodium falciparum)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Plasmodium falciparum)
CIT [cytosol]
Metabolism of vitamins and cofactors (Plasmodium falciparum)
Metabolism of cofactors (Plasmodium falciparum)
NADPH regeneration (Plasmodium falciparum)
ACO1:4Fe-4S isomerises CIT to ISCIT (Plasmodium falciparum)
CIT [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Glycolysis (Rattus norvegicus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Rattus norvegicus)
CIT [cytosol]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Carnitine metabolism (Rattus norvegicus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Rattus norvegicus)
ACLY tetramer transforms CIT to Ac-CoA (Rattus norvegicus)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Rattus norvegicus)
CIT [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of cofactors (Rattus norvegicus)
NADPH regeneration (Rattus norvegicus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Rattus norvegicus)
CIT [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Rattus norvegicus)
NACT co-transports trivalent citrate and a sodium ion (Rattus norvegicus)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Rattus norvegicus)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Organic anion transporters (Rattus norvegicus)
SLC25A1 exchanges CIT and MAL (Rattus norvegicus)
CIT [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Glycolysis (Saccharomyces cerevisiae)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Saccharomyces cerevisiae)
CIT [cytosol]
Metabolism of lipids (Saccharomyces cerevisiae)
Fatty acid metabolism (Saccharomyces cerevisiae)
Carnitine metabolism (Saccharomyces cerevisiae)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Saccharomyces cerevisiae)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Saccharomyces cerevisiae)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Saccharomyces cerevisiae)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Saccharomyces cerevisiae)
CIT [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of inorganic cations/anions and amino acids/oligopeptides (Saccharomyces cerevisiae)
Organic anion transporters (Saccharomyces cerevisiae)
SLC25A1 exchanges CIT and MAL (Saccharomyces cerevisiae)
CIT [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Glycolysis (Schizosaccharomyces pombe)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Schizosaccharomyces pombe)
CIT [cytosol]
Metabolism of lipids (Schizosaccharomyces pombe)
Fatty acid metabolism (Schizosaccharomyces pombe)
Carnitine metabolism (Schizosaccharomyces pombe)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Schizosaccharomyces pombe)
ACLY tetramer transforms CIT to Ac-CoA (Schizosaccharomyces pombe)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Schizosaccharomyces pombe)
CIT [cytosol]
Transport of small molecules (Schizosaccharomyces pombe)
SLC-mediated transmembrane transport (Schizosaccharomyces pombe)
Transport of inorganic cations/anions and amino acids/oligopeptides (Schizosaccharomyces pombe)
Organic anion transporters (Schizosaccharomyces pombe)
SLC25A1 exchanges CIT and MAL (Schizosaccharomyces pombe)
CIT [cytosol]
Metabolism (Sus scrofa)
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Glycolysis (Sus scrofa)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Sus scrofa)
CIT [cytosol]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Carnitine metabolism (Sus scrofa)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Sus scrofa)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Sus scrofa)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Sus scrofa)
ACLY tetramer transforms CIT to Ac-CoA (Sus scrofa)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Sus scrofa)
CIT [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of cofactors (Sus scrofa)
NADPH regeneration (Sus scrofa)
ACO1:4Fe-4S isomerises CIT to ISCIT (Sus scrofa)
CIT [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Sus scrofa)
NACT co-transports trivalent citrate and a sodium ion (Sus scrofa)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Sus scrofa)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Sus scrofa)
Organic anion transporters (Sus scrofa)
SLC25A1 exchanges CIT and MAL (Sus scrofa)
CIT [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Carnitine metabolism (Xenopus tropicalis)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)
CIT [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)
CIT [cytosol]
Fatty acyl-CoA biosynthesis (Xenopus tropicalis)
ACLY tetramer transforms CIT to Ac-CoA (Xenopus tropicalis)
CIT [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Xenopus tropicalis)
CIT [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of cofactors (Xenopus tropicalis)
NADPH regeneration (Xenopus tropicalis)
ACO1:4Fe-4S isomerises CIT to ISCIT (Xenopus tropicalis)
CIT [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Xenopus tropicalis)
NACT co-transports trivalent citrate and a sodium ion (Xenopus tropicalis)
CIT [cytosol]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Xenopus tropicalis)
Dicarboxylates transported by NaDC1 [cytosol]
CIT [cytosol]
Transport of inorganic cations/anions and amino acids/oligopeptides (Xenopus tropicalis)
Organic anion transporters (Xenopus tropicalis)
SLC25A1 exchanges CIT and MAL (Xenopus tropicalis)
CIT [cytosol]
External Reference Information
External Reference
citric acid [ChEBI:30769]
Participates
as an input of
phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] (Gallus gallus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Drosophila melanogaster)
ACO1:4Fe-4S isomerises CIT to ISCIT (Homo sapiens)
ACO1:4Fe-4S isomerises CIT to ISCIT (Mus musculus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Rattus norvegicus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Canis familiaris)
ACO1:4Fe-4S isomerises CIT to ISCIT (Bos taurus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Sus scrofa)
ACO1:4Fe-4S isomerises CIT to ISCIT (Danio rerio)
ACO1:4Fe-4S isomerises CIT to ISCIT (Xenopus tropicalis)
ACO1:4Fe-4S isomerises CIT to ISCIT (Gallus gallus)
ACO1:4Fe-4S isomerises CIT to ISCIT (Caenorhabditis elegans)
ACO1:4Fe-4S isomerises CIT to ISCIT (Dictyostelium discoideum)
ACO1:4Fe-4S isomerises CIT to ISCIT (Plasmodium falciparum)
ACLY tetramer transforms CIT to Ac-CoA (Homo sapiens)
ACLY tetramer transforms CIT to Ac-CoA (Mus musculus)
ACLY tetramer transforms CIT to Ac-CoA (Rattus norvegicus)
ACLY tetramer transforms CIT to Ac-CoA (Canis familiaris)
ACLY tetramer transforms CIT to Ac-CoA (Bos taurus)
ACLY tetramer transforms CIT to Ac-CoA (Sus scrofa)
ACLY tetramer transforms CIT to Ac-CoA (Danio rerio)
ACLY tetramer transforms CIT to Ac-CoA (Xenopus tropicalis)
ACLY tetramer transforms CIT to Ac-CoA (Gallus gallus)
ACLY tetramer transforms CIT to Ac-CoA (Drosophila melanogaster)
ACLY tetramer transforms CIT to Ac-CoA (Caenorhabditis elegans)
ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)
ACLY tetramer transforms CIT to Ac-CoA (Schizosaccharomyces pombe)
as an output of
NACT co-transports trivalent citrate and a sodium ion (Caenorhabditis elegans)
NACT co-transports trivalent citrate and a sodium ion (Drosophila melanogaster)
NACT co-transports trivalent citrate and a sodium ion (Gallus gallus)
NACT co-transports trivalent citrate and a sodium ion (Xenopus tropicalis)
NACT co-transports trivalent citrate and a sodium ion (Sus scrofa)
NACT co-transports trivalent citrate and a sodium ion (Bos taurus)
NACT co-transports trivalent citrate and a sodium ion (Canis familiaris)
NACT co-transports trivalent citrate and a sodium ion (Rattus norvegicus)
SLC25A1 exchanges CIT and MAL (Homo sapiens)
SLC25A1 exchanges CIT and MAL (Mus musculus)
SLC25A1 exchanges CIT and MAL (Rattus norvegicus)
SLC25A1 exchanges CIT and MAL (Canis familiaris)
SLC25A1 exchanges CIT and MAL (Bos taurus)
SLC25A1 exchanges CIT and MAL (Sus scrofa)
SLC25A1 exchanges CIT and MAL (Danio rerio)
SLC25A1 exchanges CIT and MAL (Xenopus tropicalis)
SLC25A1 exchanges CIT and MAL (Gallus gallus)
SLC25A1 exchanges CIT and MAL (Drosophila melanogaster)
SLC25A1 exchanges CIT and MAL (Caenorhabditis elegans)
SLC25A1 exchanges CIT and MAL (Schizosaccharomyces pombe)
SLC25A1 exchanges CIT and MAL (Saccharomyces cerevisiae)
NACT co-transports trivalent citrate and a sodium ion (Homo sapiens)
NACT co-transports trivalent citrate and a sodium ion (Mus musculus)
as a member of
weak acid [cytosol]
Dicarboxylates transported by NaDC1 [cytosol]
This entity regulates
Negatively
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Saccharomyces cerevisiae)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Schizosaccharomyces pombe)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Caenorhabditis elegans)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Drosophila melanogaster)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Gallus gallus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Danio rerio)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Sus scrofa)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Bos taurus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Canis familiaris)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Rattus norvegicus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Mus musculus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Homo sapiens)
Positively
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Plasmodium falciparum)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Schizosaccharomyces pombe)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Dictyostelium discoideum)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Sus scrofa)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Bos taurus)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Canis familiaris)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Rattus norvegicus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Plasmodium falciparum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Schizosaccharomyces pombe)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Dictyostelium discoideum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Gallus gallus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Sus scrofa)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Bos taurus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Canis familiaris)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Rattus norvegicus)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Plasmodium falciparum)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Schizosaccharomyces pombe)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Dictyostelium discoideum)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Gallus gallus)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Sus scrofa)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Bos taurus)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Canis familiaris)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Rattus norvegicus)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Homo sapiens)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Mus musculus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Mus musculus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Homo sapiens)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Mus musculus)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Saccharomyces cerevisiae)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Caenorhabditis elegans)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Drosophila melanogaster)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Xenopus tropicalis)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Homo sapiens)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Saccharomyces cerevisiae)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Caenorhabditis elegans)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Drosophila melanogaster)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA
(Xenopus tropicalis)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Saccharomyces cerevisiae)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Caenorhabditis elegans)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Drosophila melanogaster)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
(Xenopus tropicalis)
Other forms of this molecule
CIT [extracellular region]
Cross References
Guide to Pharmacology - Ligands
2478
COMPOUND
C00158
PubChem Substance
11533259
HMDB Metabolite
HMDB0000094
ZINC
000000895081
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![CIT [cytosol] icon](/icon/R-ICO-013816.svg){kind=icon}
