oxaloacetate + NADH + H+ <=> malate + NAD+

Stable Identifier
R-GGA-372422
Type
Reaction [transition]
Species
Gallus gallus
Compartment
mitochondrial matrix
ReviewStatus
5/5
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oxaloacetate + NADH + H+ <=> malate + NAD+
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Oxaloacetate is reversibly reduced by NADH + H+ to form malate and NAD+. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial malate dehydrogenase (MDH2) has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from the known properties of mammalian MDH2 (Wolfe & Neilands 1956).
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L-malate dehydrogenase activity of MDH2 [mitochondrial matrix]

Physical Entity
MDH2 [mitochondrial matrix] (Gallus gallus)
Activity
L-malate dehydrogenase activity (GO:0030060)
Authored
D'Eustachio, P  (2008-09-10)
Reviewed
Harris, RA  (2008-09-10)
Created
D'Eustachio, P  (2008-06-25)
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