TICAM1, RIP1-mediated IKK complex recruitment

Stable Identifier
R-HSA-168927
Type
Pathway
Species
Homo sapiens
Related Species
Influenza A virus, Rotavirus, Hepatitis B virus, Hepatitis C Virus, Human herpesvirus 1
ReviewStatus
5/5
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TICAM1, RIP1-mediated IKK complex recruitment
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Receptor-interacting protein 1 (RIP1) mediates the activation of interferon-alpha/beta via intermediate activation of IKK/TBK1 or NFkB pathways.
Literature References
PubMed ID Title Journal Year
16115877 Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

Fitzgerald, KA, Cusson-Hermance, N, Khurana, S, Kelliher, MA, Lee, TH

J Biol Chem 2005
15064760 RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B

Blancheteau, V, Meylan, E, Burns, K, Kelliher, M, Tschopp, J, Martinon, F, Hofmann, K

Nat Immunol 2004
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MyD88-independent toll-like receptor signaling pathway (0002756)
Cross References
BioModels Database
Authored
Luo, F  (2005-11-10)
Reviewed
Fitzgerald, KA  (2012-11-13)
Gay, NJ  (2006-04-24)
Created
de Bono, B  (2005-11-22)
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