AKT phosphorylates targets in the cytosol

Stable Identifier
R-HSA-198323
Type
Pathway
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Following activation, AKT can phosphorylate an array of target proteins in the cytoplasm, many of which are involved in cell survival control. Phosphorylation of TSC2 feeds positively to the TOR kinase, which, in turn, contributes to AKT activation (positive feedback loop).
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Event Information
Go Biological Process
Orthologous Events
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