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PDK1:PIP2,PIP3 [plasma membrane]
Stable Identifier
R-HSA-202311
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
PDK1 bound to either PIP3 or PI(3,4)P2
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
Activation of IKK complex (Homo sapiens)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Activation of TAK1-TAB2 complex (Homo sapiens)
TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Auto-ubiquitination of TRAF6 (Homo sapiens)
TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Interaction and oligomerization of MALT1 to Bcl10 (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Interaction of Bcl10 to CARMA1 (Homo sapiens)
Bcl10 bound to CARMA1 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Oligomerization of Bcl10 (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Oligomerization of CARMA1 (Homo sapiens)
Activated CARMA1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Phosphorylation of Bcl10 (Homo sapiens)
Bcl10 bound to CARMA1 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Phosphorylation of CARMA1 (Homo sapiens)
Activated CARMA1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
CARMA1 bound to PDK1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Phosphorylation of PKC theta (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Translocation of CARMA1 to Plasma membrane (Homo sapiens)
CARMA1 bound to PDK1 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Translocation of PDK1 to Plasma membrane (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Translocation of TRAF6 to CBM complex (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Ubiquitination of NEMO by TRAF6 (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
Ubiquitination of NEMO by TRAF6 (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated NF-kB activation (Homo sapiens)
Ubiquitination of NEMO by TRAF6 (Homo sapiens)
Ub-TRAF6 trimer bound to CBM complex [plasma membrane] (Homo sapiens)
MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane] (Homo sapiens)
Bcl10 trimer bound to CARMA1 trimer [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Role of LAT2/NTAL/LAB on calcium mobilization (Homo sapiens)
Translocation of PDK1 to Plasma membrane (Homo sapiens)
PDK1:PIP2,PIP3 [plasma membrane] (Homo sapiens)
Participants
components
PDPK1 [plasma membrane]
(Homo sapiens)
PIP3, PI(3,4)P2 [plasma membrane]
Participates
as an output of
Translocation of PDK1 to Plasma membrane (Homo sapiens)
as an input of
Translocation of CARMA1 to Plasma membrane (Homo sapiens)
as a component of
CARMA1 bound to PDK1 [plasma membrane] (Homo sapiens)
Activated CARMA1 [plasma membrane] (Homo sapiens)
CARMA1 trimer [plasma membrane] (Homo sapiens)
Inferred To
PDK1:PIP2,PIP3 [plasma membrane]
(Bos taurus)
PDK1:PIP2,PIP3 [plasma membrane]
(Caenorhabditis elegans)
PDK1:PIP2,PIP3 [plasma membrane]
(Canis familiaris)
PDK1:PIP2,PIP3 [plasma membrane]
(Danio rerio)
PDK1:PIP2,PIP3 [plasma membrane]
(Dictyostelium discoideum)
PDK1:PIP2,PIP3 [plasma membrane]
(Drosophila melanogaster)
PDK1:PIP2,PIP3 [plasma membrane]
(Gallus gallus)
PDK1:PIP2,PIP3 [plasma membrane]
(Mus musculus)
PDK1:PIP2,PIP3 [plasma membrane]
(Plasmodium falciparum)
PDK1:PIP2,PIP3 [plasma membrane]
(Rattus norvegicus)
PDK1:PIP2,PIP3 [plasma membrane]
(Saccharomyces cerevisiae)
PDK1:PIP2,PIP3 [plasma membrane]
(Schizosaccharomyces pombe)
PDK1:PIP2,PIP3 [plasma membrane]
(Sus scrofa)
PDK1:PIP2,PIP3 [plasma membrane]
(Xenopus tropicalis)
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