Synthesis of 5-eicosatetraenoic acids

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R-HSA-2142688
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Pathway
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Homo sapiens
ReviewStatus
5/5
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5-hydroperoxy-eicosatetraenoic acid (5-HpETE), 5-hydroxyeicosatetraenoic acid (5S-HETE) and 5-oxo-eicosatetraenoic acid (5-oxoETE) are formed after the initial step of arachidonic acid oxidation by arachidonate 5-lipoxygenase (ALOX5) (Buczynski et al. 2009, Vance & Vance 2008).
Literature References
PubMed ID Title Journal Year
  Biochemistry of Lipids, Lipoproteins and Membranes, 5th Edition

Vance, JE, Vance, DE

  2008
19244215 Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology

Dumlao, DS, Buczynski, MW, Dennis, EA

J Lipid Res 2009
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