Reactome | p-S387-RFWD2:p-S15-TP53 [nucleoplasm]

p-S387-RFWD2:p-S15-TP53 [nucleoplasm]

Stable Identifier

R-HSA-349420

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Phospho-COP1(Ser-387):p53 complex

Locations in the PathwayBrowser

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Cell Cycle (Homo sapiens)

- Cell Cycle Checkpoints (Homo sapiens)
  - G1/S DNA Damage Checkpoints (Homo sapiens)
    - p53-Dependent G1/S DNA damage checkpoint (Homo sapiens)
      - p53-Dependent G1 DNA Damage Response (Homo sapiens)
        
        Stabilization of p53 (Homo sapiens)
        
        Autodegradation of the E3 ubiquitin ligase COP1 (Homo sapiens)
        
        Dissociation of the COP1-p53 complex (Homo sapiens)
        
        p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Homo sapiens)

Participants

components

Participates

as an input of

Dissociation of the COP1-p53 complex (Homo sapiens)

Inferred To

p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Bos taurus)

p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Canis familiaris)

p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Danio rerio)

p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Mus musculus)

p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Rattus norvegicus)

p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Sus scrofa)

p-S387-RFWD2:p-S15-TP53 [nucleoplasm] (Xenopus tropicalis)

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