DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2 [nucleoplasm]

Stable Identifier
R-HSA-5683737
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
12364621 53BP1, a mediator of the DNA damage checkpoint.

Elledge, SJ, Carpenter, PB, Wang, B, Matsuoka, S

Science 2002
19001859 NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway

Stern, DF, Wilson, KA

Cell Cycle 2008
Participants
Participates
Inferred To
Cite Us!