p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm]

Stable Identifier
R-HSA-6804745
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
21986495 Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage

Chen, L, Chen, J, Cheng, Q, Li, B, Cross, B, Li, Z

Mol. Cell. Biol. 2011
21730132 Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

Pant, V, Quintás-Cardama, A, Iwakuma, T, Lozano, G, Xiong, S

Proc. Natl. Acad. Sci. U.S.A. 2011
21730163 The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo

Ganapathy, S, Wang, ZG, Liao, X, Yang, J, Li, Y, Yuan, ZM, Shadfan, M, Kawai, H, Zuo, Y, Huang, L, Yan, Z

Proc. Natl. Acad. Sci. U.S.A. 2011
Participants
members
Participates
as an output of
as an input of
as a component of
Inferred To
p-S166,S188-MDM2 dimer [nucleoplasm] (Bos taurus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Sus scrofa)
p-S166,S188-MDM2 dimer [nucleoplasm] (Xenopus tropicalis)
p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] (Canis familiaris)
p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] (Danio rerio)
p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] (Mus musculus)
p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] (Rattus norvegicus)
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