2xPDXK:2xZn2+ phosphorylates PXL

Stable Identifier
R-HSA-964970
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
PLP results from phosphorylation of pyridoxal
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Pyridoxal kinase (PDXK) catalyzes the ATP-dependent phosphorylation of pyridoxal (PXL) to form pyridoxal 5'-phosphate (PXLP) (Lee et al. 2000, di Salvo et al. 2004).
Literature References
PubMed ID Title Journal Year
10987144 Human pyridoxal kinase: overexpression and properties of the recombinant enzyme

Moon, BJ, Kwon, OS, Lee, HS, Choi, SY

Mol Cells 2000
15249053 Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases

di Salvo, ML, Schirch, V, Hunt, S

Protein Expr Purif 2004
Participants
Participates
Catalyst Activity

pyridoxal kinase activity of 2xPDXK:2xZn2+ [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
Cite Us!