IFI16 ligands [cytosol]

Stable Identifier
R-NUL-9013802
Type
Set [DefinedSet]
Species
Human immunodeficiency virus 1
Compartment
cytosol
GO Cellular Component
host cell cytosol (0044164)
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
23345332 Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

Fitzgerald, KA, Rasmussen, SB, Søby, S, Kurt-Jones, E, Holm, CK, Horan, KA, Jakobsen, MR, Landolfo, S, Unterholzner, L, Paludan, SR, Melchjorsen, J, Iversen, MB, Damania, B, West, JA, Thompson, M, Hansen, K, Ellermann-Eriksen, S, Bowie, AG

J. Immunol. 2013
24154727 IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

Mogensen, TH, Fitzgerald, KA, Bak, RO, Tengchuan, J, Xiao, TS, Jakobsen, MR, Paludan, SR, Mikkelsen, JG, Jin, T, Jensen, SB, Ostergaard, L, Hansen, K, Berg, RK, Andersen, A, Laustsen, A

Proc. Natl. Acad. Sci. U.S.A. 2013
28186168 IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP

Johannsen, M, Jakobsen, MR, Laustsen, A, Mohammadi, P, Hotter, D, Sørensen, LK, Paludan, SR, Jensen, SB, Kjolby, M, Skipper, KA, Sun, C, Thavachelvam, K, Jønsson, KL, Nyegaard, M, Egedal, JH, Kirchhoff, F, Krapp, C, Lebbink, RJ, Prabakaran, T, Mikkelsen, JG, Holm, CK

Nat Commun 2017
24970844 Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway

Jensen, SB, Prabakaran, T, Hansen, K, Horan, KA, Jørgensen, SE, Laustsen, A, Jakobsen, MR, Rahbæk, SH, Leber, JH, Nielsen, R, Decker, T, Paludan, SR

EMBO J. 2014
Participants
members
Participates
as an input of
as a component of
Disease
Name Identifier Synonyms
bacterial infectious disease DOID:104
viral infectious disease DOID:934 Viral disease, virus infection, virus infection
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