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Gene: Lrrc4b (leucine rich repeat containing 4B) Rattus norvegicus

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Symbol:

Lrrc4b

Name:

leucine rich repeat containing 4B

RGD ID:

1307121

Description:

Predicted to enable signaling receptor binding activity. Involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human LRRC4B (leucine rich repeat containing 4B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bis(2-ethylhexyl) phthalate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Leucine-rich repeat-containing protein 4B; LOC308571; Lrig4; netrin-G3 ligand; NGL-3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,058,558 - 104,092,831 (+)	NCBI		GRCr8
mRatBN7.2	1	94,922,034 - 94,956,309 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	94,935,603 - 94,956,263 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,321,012 - 100,341,710 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	108,793,656 - 108,814,358 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,084,084 - 102,104,779 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,434,418 - 100,468,914 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,447,998 - 100,468,868 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,500,129 - 101,534,301 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	94,920,886 - 94,940,636 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	94,998,996 - 95,018,701 (+)	NCBI
Celera	1	89,198,185 - 89,218,975 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc4b	Rat	17beta-estradiol	decreases expression	ISO	LRRC4B (Homo sapiens)	6480464	Estradiol results in decreased expression of LRRC4B mRNA	CTD	PMID:31614463
Lrrc4b	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of LRRC4B mRNA	CTD	PMID:32109520
Lrrc4b	Rat	2,3,7,8-Tetrachlorodibenzofuran	decreases expression	EXP		6480464	2 more ...	CTD	PMID:32109520
Lrrc4b	Rat	3,4-methylenedioxymethamphetamine	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of LRRC4B mRNA	CTD	PMID:20188158
Lrrc4b	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	Lrrc4b (Mus musculus)	6480464	bisphenol S results in decreased methylation of LRRC4B exon	CTD	PMID:33297965
Lrrc4b	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	Lrrc4b (Mus musculus)	6480464	bisphenol S affects the methylation of LRRC4B gene	CTD	PMID:31683443
Lrrc4b	Rat	Aflatoxin B2 alpha	increases methylation	ISO	LRRC4B (Homo sapiens)	6480464	aflatoxin B2 results in increased methylation of LRRC4B intron	CTD	PMID:30157460
Lrrc4b	Rat	all-trans-retinoic acid	multiple interactions	ISO	Lrrc4b (Mus musculus)	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC4B mRNA	CTD	PMID:36189433
Lrrc4b	Rat	benzo[a]pyrene	increases methylation	ISO	LRRC4B (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of LRRC4B 3' UTR more ...	CTD	PMID:27901495
Lrrc4b	Rat	benzo[a]pyrene	affects methylation	ISO	LRRC4B (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of LRRC4B 5' UTR and Benzo(a)pyrene affects the methylation of LRRC4B intron	CTD	PMID:27901495 and PMID:30157460
Lrrc4b	Rat	benzo[e]pyrene	increases methylation	ISO	LRRC4B (Homo sapiens)	6480464	benzo(e)pyrene results in increased methylation of LRRC4B intron	CTD	PMID:30157460
Lrrc4b	Rat	bis(2-ethylhexyl) phthalate	multiple interactions	EXP		6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA	CTD	PMID:31199487
Lrrc4b	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of LRRC4B mRNA	CTD	PMID:25181051 more ...
Lrrc4b	Rat	bisphenol A	decreases expression	ISO	Lrrc4b (Mus musculus)	6480464	bisphenol A results in decreased expression of LRRC4B mRNA	CTD	PMID:32156529
Lrrc4b	Rat	bisphenol A	decreases methylation	ISO	LRRC4B (Homo sapiens)	6480464	bisphenol A results in decreased methylation of LRRC4B gene	CTD	PMID:31601247
Lrrc4b	Rat	bisphenol A	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	bisphenol A results in increased expression of LRRC4B mRNA	CTD	PMID:35479511
Lrrc4b	Rat	Butylbenzyl phthalate	multiple interactions	EXP		6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA	CTD	PMID:31199487
Lrrc4b	Rat	chlorpyrifos	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	Chlorpyrifos results in increased expression of LRRC4B mRNA	CTD	PMID:37019170
Lrrc4b	Rat	clobetasol	decreases expression	ISO	Lrrc4b (Mus musculus)	6480464	Clobetasol results in decreased expression of LRRC4B mRNA	CTD	PMID:27462272
Lrrc4b	Rat	decabromodiphenyl ether	increases expression	EXP		6480464	decabromobiphenyl ether results in increased expression of LRRC4B mRNA	CTD	PMID:23640034
Lrrc4b	Rat	dibutyl phthalate	decreases expression	EXP		6480464	Dibutyl Phthalate results in decreased expression of LRRC4B mRNA	CTD	PMID:21266533
Lrrc4b	Rat	dibutyl phthalate	multiple interactions	EXP		6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA	CTD	PMID:31199487
Lrrc4b	Rat	dichloroacetic acid	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	Dichloroacetic Acid results in increased expression of LRRC4B mRNA	CTD	PMID:28962523
Lrrc4b	Rat	dieldrin	affects methylation	ISO	Lrrc4b (Mus musculus)	6480464	Dieldrin affects the methylation of LRRC4B gene	CTD	PMID:38995845
Lrrc4b	Rat	diethyl phthalate	multiple interactions	EXP		6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA	CTD	PMID:31199487
Lrrc4b	Rat	diisobutyl phthalate	multiple interactions	EXP		6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA	CTD	PMID:31199487
Lrrc4b	Rat	diisononyl phthalate	multiple interactions	EXP		6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA	CTD	PMID:31199487
Lrrc4b	Rat	doxorubicin	decreases expression	ISO	LRRC4B (Homo sapiens)	6480464	Doxorubicin results in decreased expression of LRRC4B mRNA	CTD	PMID:29803840
Lrrc4b	Rat	endosulfan	decreases expression	EXP		6480464	Endosulfan results in decreased expression of LRRC4B mRNA	CTD	PMID:31464424
Lrrc4b	Rat	ethanol	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	Ethanol results in increased expression of LRRC4B mRNA	CTD	PMID:30319688
Lrrc4b	Rat	fenvalerate	increases expression	EXP		6480464	fenvalerate results in increased expression of LRRC4B mRNA	CTD	PMID:30307764
Lrrc4b	Rat	methapyrilene	increases methylation	ISO	LRRC4B (Homo sapiens)	6480464	Methapyrilene results in increased methylation of LRRC4B intron	CTD	PMID:30157460
Lrrc4b	Rat	methotrexate	affects expression	ISO	Lrrc4b (Mus musculus)	6480464	Methotrexate affects the expression of LRRC4B mRNA	CTD	PMID:18502557
Lrrc4b	Rat	mono(2-ethylhexyl) phthalate	multiple interactions	ISO	Lrrc4b (Mus musculus)	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC4B mRNA	CTD	PMID:36189433
Lrrc4b	Rat	pentanal	increases expression	ISO	LRRC4B (Homo sapiens)	6480464	pentanal results in increased expression of LRRC4B mRNA	CTD	PMID:26079696
Lrrc4b	Rat	phenobarbital	affects expression	ISO	Lrrc4b (Mus musculus)	6480464	Phenobarbital affects the expression of LRRC4B mRNA	CTD	PMID:23091169
Lrrc4b	Rat	pirinixic acid	multiple interactions	ISO	Lrrc4b (Mus musculus)	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LRRC4B mRNA	CTD	PMID:19710929
Lrrc4b	Rat	pirinixic acid	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	pirinixic acid results in increased expression of LRRC4B mRNA	CTD	PMID:20813756
Lrrc4b	Rat	silicon dioxide	decreases expression	ISO	LRRC4B (Homo sapiens)	6480464	Silicon Dioxide analog results in decreased expression of LRRC4B mRNA	CTD	PMID:25895662
Lrrc4b	Rat	silicon dioxide	decreases expression	EXP		6480464	Silicon Dioxide results in decreased expression of LRRC4B mRNA	CTD	PMID:32721576
Lrrc4b	Rat	sunitinib	decreases expression	ISO	LRRC4B (Homo sapiens)	6480464	Sunitinib results in decreased expression of LRRC4B mRNA	CTD	PMID:31533062
Lrrc4b	Rat	tetracycline	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	Tetracycline results in increased expression of LRRC4B mRNA	CTD	PMID:16917069
Lrrc4b	Rat	titanium dioxide	decreases methylation	ISO	Lrrc4b (Mus musculus)	6480464	titanium dioxide results in decreased methylation of LRRC4B gene	CTD	PMID:35295148
Lrrc4b	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of LRRC4B mRNA	CTD	PMID:33387578
Lrrc4b	Rat	triptonide	increases expression	ISO	Lrrc4b (Mus musculus)	6480464	triptonide results in increased expression of LRRC4B mRNA	CTD	PMID:33045310
Lrrc4b	Rat	XL147	multiple interactions	ISO	Lrrc4b (Mus musculus)	6480464	[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of LRRC4B mRNA	CTD	PMID:27935865

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc4b	Rat	positive regulation of synapse assembly	involved_in	IBA	MGI:3027390 and PANTHER:PTN002809010	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc4b	Rat	positive regulation of synapse assembly	involved_in	ISO	Lrrc4b (Mus musculus)	1624291	PMID:21940441	RGD	PMID:21940441
Lrrc4b	Rat	regulation of postsynaptic density assembly	involved_in	IDA		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	regulation of postsynaptic density assembly	involved_in	IBA	PANTHER:PTN002809010 and Lrrc4b (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc4b	Rat	regulation of postsynaptic density assembly	involved_in	IMP		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	regulation of presynapse assembly	involved_in	IDA		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	regulation of presynapse assembly	involved_in	IBA	PANTHER:PTN002809010 and Lrrc4b (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc4b	Rat	regulation of presynapse assembly	involved_in	IMP		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	synaptic membrane adhesion	involved_in	IMP		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	synaptic membrane adhesion	involved_in	IBA	PANTHER:PTN002809010 and Lrrc4b (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc4b	Rat	synaptic membrane adhesion	involved_in	IDA		13702321	PMID:19252495	SynGO

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc4b	Rat	cerebellar mossy fiber	located_in	ISO	Lrrc4b (Mus musculus)	1624291	PMID:23791195	RGD	PMID:23791195
Lrrc4b	Rat	glutamatergic synapse	is_active_in	IMP		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	glutamatergic synapse	is_active_in	IBA	PANTHER:PTN002809010 and Lrrc4b (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc4b	Rat	glutamatergic synapse	is_active_in	IDA		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	plasma membrane	is_active_in	IBA	FB:FBgn0034718 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc4b	Rat	postsynaptic density membrane	is_active_in	IDA		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	postsynaptic density membrane	is_active_in	IBA	PANTHER:PTN002809010 and Lrrc4b (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc4b	Rat	postsynaptic density membrane	is_active_in	IEP		13702321	PMID:19252495	SynGO
Lrrc4b	Rat	presynaptic membrane	located_in	IEA	UniProtKB-SubCell:SL-0222	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc4b	Rat	protein binding	enables	ISO	Lrrc4b (Mus musculus)	1624291	PR:P70175 more ...	RGD	PMID:16980967
Lrrc4b	Rat	signaling receptor binding	enables	ISO	Lrrc4b (Mus musculus)	1624291	UniProtKB:Q64487 and PMID:21940441	RGD	PMID:21940441
Lrrc4b	Rat	signaling receptor binding	enables	IBA	MGI:3027390 and PANTHER:PTN002809010	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses.	Woo J, etal., Nat Neurosci. 2009 Apr;12(4):428-37. doi: 10.1038/nn.2279. Epub 2009 Mar 1.

PMID:16980967	PMID:21940441	PMID:23791195

Lrrc4b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,058,558 - 104,092,831 (+)	NCBI		GRCr8
mRatBN7.2	1	94,922,034 - 94,956,309 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	94,935,603 - 94,956,263 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,321,012 - 100,341,710 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	108,793,656 - 108,814,358 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,084,084 - 102,104,779 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,434,418 - 100,468,914 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,447,998 - 100,468,868 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,500,129 - 101,534,301 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	94,920,886 - 94,940,636 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	94,998,996 - 95,018,701 (+)	NCBI
Celera	1	89,198,185 - 89,218,975 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

LRRC4B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,516,892 - 50,568,435 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,516,892 - 50,568,435 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	51,020,149 - 51,071,692 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,711,961 - 55,763,114 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	48,071,474 - 48,122,624 (-)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	47,356,885 - 47,401,559 (-)	NCBI		HuRef
CHM1_1	19	51,022,007 - 51,073,080 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	53,605,741 - 53,657,264 (-)	NCBI		T2T-CHM13v2.0

Lrrc4b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,091,911 - 44,112,775 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,078,442 - 44,112,775 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	44,442,487 - 44,463,351 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,429,018 - 44,463,351 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	51,697,857 - 51,718,721 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	34,009,350 - 34,031,662 (+)	NCBI		MGSCv36	mm8
MGSCv36	7	44,310,529 - 44,331,393 (+)	NCBI		MGSCv36	mm8
Celera	7	39,905,185 - 39,905,526 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.83	NCBI

Lrrc4b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955559	621,458 - 651,007 (+)	NCBI	ChiLan1.0	ChiLan1.0

LRRC4B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	56,584,526 - 56,636,270 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	58,505,270 - 58,557,051 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	47,481,678 - 47,533,446 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	56,381,130 - 56,433,241 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	56,381,130 - 56,423,084 (-)	Ensembl	panpan1.1		panPan2

LRRC4B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,166,536 - 106,229,083 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,190,248 - 106,229,089 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	105,740,196 - 105,803,098 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	106,677,842 - 106,741,059 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	106,718,761 - 106,740,420 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,349,951 - 106,413,124 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	105,991,546 - 106,054,729 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	106,832,167 - 106,895,387 (+)	NCBI		UU_Cfam_GSD_1.0

Lrrc4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	22,452,475 - 22,474,881 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936889	328,465 - 361,778 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC4B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	55,346,908 - 55,409,991 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	55,346,787 - 55,409,876 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	51,270,128 - 51,308,888 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC4B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	43,576,143 - 43,627,921 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	23,567,526 - 23,641,715 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc4b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,043,994 - 4,062,160 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,032,976 - 4,062,198 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Lrrc4b
538 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	90
Count of miRNA genes:	79
Interacting mature miRNAs:	82
Transcripts:	ENSRNOT00000026259
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	92963855	109494029	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	101228864	146228864	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	92683681	137683681	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	92683681	137683681	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	97582336	142582336	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	101594089	146594089	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	100345976	145345976	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat

AW536033

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	104,092,511 - 104,092,772 (+)	Marker Load Pipeline
mRatBN7.2	1	94,955,989 - 94,956,250 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,468,595 - 100,468,855	NCBI	Rnor6.0
Rnor_5.0	1	101,533,982 - 101,534,242	UniSTS	Rnor5.0
RGSC_v3.4	1	94,940,317 - 94,940,577	UniSTS	RGSC3.4
Celera	1	89,218,656 - 89,218,916	UniSTS
RH 3.4 Map	1	905.8	UniSTS
Cytogenetic Map	1	q22	UniSTS

RH143851

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	94,955,707 - 94,955,986 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,468,313 - 100,468,591	NCBI	Rnor6.0
Rnor_5.0	1	101,533,700 - 101,533,978	UniSTS	Rnor5.0
RGSC_v3.4	1	94,940,035 - 94,940,313	UniSTS	RGSC3.4
Celera	1	89,218,374 - 89,218,652	UniSTS
RH 3.4 Map	1	906.8	UniSTS
Cytogenetic Map	1	q22	UniSTS

AU048550

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	94,951,456 - 94,951,682 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	100,464,064 - 100,464,287	NCBI	Rnor6.0
Rnor_5.0	1	101,529,451 - 101,529,674	UniSTS	Rnor5.0
RGSC_v3.4	1	94,935,520 - 94,935,743	UniSTS	RGSC3.4
Celera	1	89,214,125 - 89,214,348	UniSTS
Cytogenetic Map	1	q22	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	90	89	58	25	58	6	216	97	93	44	60	31


RefSeq Transcripts	NM_001271081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026259 ⟹ ENSRNOP00000026259

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	94,935,603 - 94,956,263 (+)	Ensembl
Rnor_6.0 Ensembl	1	100,447,998 - 100,468,868 (+)	Ensembl

RefSeq Acc Id:

NM_001271081 ⟹ NP_001258010

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,072,128 - 104,092,831 (+)	NCBI
mRatBN7.2	1	94,935,603 - 94,956,309 (+)	NCBI
Rnor_6.0	1	100,447,998 - 100,468,914 (+)	NCBI
Rnor_5.0	1	101,500,129 - 101,534,301 (+)	NCBI
Celera	1	89,198,185 - 89,218,975 (+)	NCBI

Sequence:

show sequence

GGCCTGGGGCACAGAGAGAAGGCCATCGGAAGCCGAGCCGCCAGGCCCCCCAGCGTACCCTCGGAGTATGAACATTGAGGATGGCGCAGGCCCACATCCAAGGCTCCCCGTGCCCCTTGCTGCCGCCT
GGTAGGATGTCCTGGCCCCAAGGGGCTCTCCTGCTCCTGTGGCTCTTCTCCCCACCCCTGAGGGCCGGTGGGGGCGGTGTGGCCGTGACTTCAGCCGCCGGAGGAGGCTCCCCGCCAGCCACCTCCTG
CCCAGCAGCCTGCTCCTGCAGCAACCAGGCCAGCCGGGTGATCTGCACGCGGAGGGAGCTGGCCGAGGTGCCAGCCAGTATCCCCGTCAATACCCGCTACCTGAACTTGCAAGAGAACAGCATTCAGG
TGATCCGCACTGACACATTCAAGCACCTCCGGCACCTGGAGATCCTGCAGCTGAGCAAGAATCTGGTGCGCAAGATCGAAGTGGGGGCGTTCAATGGGCTTCCCAGTCTCAACACACTGGAACTCTTC
GACAACCGGCTGACCACAGTGCCCACACAGGCCTTTGAGTACTTGTCCAAGCTCCGGGAGCTGTGGCTGCGCAACAACCCCATCGAAAGCATCCCATCCTATGCCTTCAACCGTGTGCCCTCATTGCG
CCGCCTGGACCTGGGCGAGCTGAAGCGTCTGGAGTACATATCGGAGGCGGCCTTCGAGGGGCTGGTGAACCTGCGCTACCTCAACCTGGGCATGTGCAACCTAAAGGACATCCCCAACCTCACAGCAC
TTGTGCGCCTGGAAGAGCTGGAGCTGTCGGGGAACCGGCTGGACCTAATTCGCCCCGGCTCCTTCCAGGGCCTCACCAGCCTGCGCAAGCTGTGGCTGATGCATGCCCAAGTGGCCACCATCGAGCGA
AACGCCTTCGACGACCTCAAGTCGCTGGAGGAGCTGAACCTGTCCCACAACAACCTGATGTCGCTGCCGCACGACCTTTTCACACCCCTTCACCGCCTGGAGCGTGTCCACCTGAACCACAACCCCTG
GCACTGCAACTGTGATGTGCTCTGGCTCAGCTGGTGGCTGAAGGAGACAGTGCCCAGCAATACCACATGCTGCGCACGCTGCCACGCGCCCGCCGGCCTCAAGGGCCGCTACATCGGTGAGCTGGACC
AGTCGCACTTCACCTGCTATGCCCCAGTCATCGTGGAGCCACCCACAGACCTCAATGTCACCGAGGGCATGGCGGCCGAGCTCAAGTGCCGCACAGGTACATCCATGACCTCGGTCAACTGGCTGACA
CCTAACGGCACGCTCATGACACACGGTTCCTATCGTGTGCGCATTTCGGTACTGCACGATGGCACACTCAATTTCACTAATGTCACCGTGCAGGACACGGGCCAGTACACGTGCATGGTGACAAACTC
TGCTGGCAACACCACTGCCTCGGCCACGCTTAACGTGTCGGCCGTGGACCCTGTGGCTGCCGGAGGGCCCGGTGGCGGGGGCCCAGGGGGTGGGGGCGGTGCAGGGGGTGCGGGCGGCTACACCTACT
TCACCACGGTGACTGTGGAGACGCTGGAGACACAGCCGGGGGAGGAGGCCCAGCAGCCCCGAGGTACTGAGAAGGAGCCCCCGGGGCCCACGACTGATGGCGCGTGGGGTGGCGGCCGGCCTGACGCT
GCAGCCCCGGCCTCAGCGTCCACCACGGCACCAGCCCCGCGCTCCTCGCGGCCCACAGAGAAGGCTTTCACGGTGCCCATCACGGACGTGACGGAGAACGCACTTAAGGACCTAGACGATGTCATGAA
GACCACCAAAATCATCATCGGCTGCTTCGTGGCCATCACCTTTATGGCCGCCGTGATGCTGGTGGCCTTCTACAAGCTGCGCAAGCAGCACCAGCTGCACAAGCACCATGGGCCCACGCGCACTGTGG
AGATCATCAACGTGGAGGACGAGCTGCCCGCCGCCTCCGCTGTGTCGGTGGCTGCGGCCGCTGCGGTGGCTGGAGGCGCGGGCGTGGGTGGGGACAGCCACCTGGCTCTTCCGGCGCTGGAGCGAGAC
CACCTCAACCACCACCACTACGTGGCGGCTGCCTTCAAGGCGCACTACGGCGGCAATCCAGGAGGCGGGTGCGGGGCCAAGGGCCCCGGCCTCAACTCCATCCACGAACCTCTGCTCTTCAAGAGCGG
CTCCAAGGAGAACGTGCAAGAGACACAAATCTAAACTTAGGCGCGCGGGGACGCGGGGACGCAGGACGCCTGCCCGAGATGCTCCTGCTTACCCAGCAGCCCTGGCGGCGCCTGCCTGTCCTGCAATG
GGAAAGGACCTGGAGATCAGGAGAGGTGGCCCCACCCTCCGCCTTGCCGTGTCCTCTGCCCACCTGCCCTGCCCGCCACCTTCCTGGGTTGAGGAGCTTCTTCGAGGGGTACCCTTTCCCCTCATCCC
AACAACCCTTCTTTTATGGCTCTTTCTTTTTTCTTTATTTCTTTGTTTTTTCCCCCTTTTGCAGTTTGACGCCTGTCCGTCCCTCCTACTCCACCACCCTCAAAACACAAGAGACAGACAACTTCACC
AGAGCCCAGGGGGCAACTCCGACAGTGTCCCCAACAGCGAGCTCCACTCGCGGCCCTGGCCGGCCCTACTCACCCCACAGACTCTTTTGATACTGAAGGGAGGTTTGCGTCAATCACTACCTGCTCTG
TAATTACTTTAAAAAAAAAAAAAAAAACACGGAAAAAGTAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006229055 ⟹ XP_006229117

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	104,058,558 - 104,092,549 (+)	NCBI
mRatBN7.2	1	94,922,034 - 94,956,291 (+)	NCBI
Rnor_6.0	1	100,434,418 - 100,468,889 (+)	NCBI
Rnor_5.0	1	101,500,129 - 101,534,301 (+)	NCBI

Sequence:

show sequence

CGGAGCCGCGACCCCGAGGACGCCCCCGGCCCAGGCCCCGCGCCCCGAGCGGACCCCGCGGGGC
ATGCCGCCCCTCGCCGGGAGCCCGGAGCCCGCGCCCCCCAGCGTACCCTCGGAGTATGAACATTGAGGATGGCGCAGGCCCACATCCAAGGCTCCCCGTGCCCCTTGCTGCCGCCTGGTAGGATGTCC
TGGCCCCAAGGGGCTCTCCTGCTCCTGTGGCTCTTCTCCCCACCCCTGAGGGCCGGTGGGGGCGGTGTGGCCGTGACTTCAGCCGCCGGAGGAGGCTCCCCGCCAGCCACCTCCTGCCCAGCAGCCTG
CTCCTGCAGCAACCAGGCCAGCCGGGTGATCTGCACGCGGAGGGAGCTGGCCGAGGTGCCAGCCAGTATCCCCGTCAATACCCGCTACCTGAACTTGCAAGAGAACAGCATTCAGGTGATCCGCACTG
ACACATTCAAGCACCTCCGGCACCTGGAGATCCTGCAGCTGAGCAAGAATCTGGTGCGCAAGATCGAAGTGGGGGCGTTCAATGGGCTTCCCAGTCTCAACACACTGGAACTCTTCGACAACCGGCTG
ACCACAGTGCCCACACAGGCCTTTGAGTACTTGTCCAAGCTCCGGGAGCTGTGGCTGCGCAACAACCCCATCGAAAGCATCCCATCCTATGCCTTCAACCGTGTGCCCTCATTGCGCCGCCTGGACCT
GGGCGAGCTGAAGCGTCTGGAGTACATATCGGAGGCGGCCTTCGAGGGGCTGGTGAACCTGCGCTACCTCAACCTGGGCATGTGCAACCTAAAGGACATCCCCAACCTCACAGCACTTGTGCGCCTGG
AAGAGCTGGAGCTGTCGGGGAACCGGCTGGACCTAATTCGCCCCGGCTCCTTCCAGGGCCTCACCAGCCTGCGCAAGCTGTGGCTGATGCATGCCCAAGTGGCCACCATCGAGCGAAACGCCTTCGAC
GACCTCAAGTCGCTGGAGGAGCTGAACCTGTCCCACAACAACCTGATGTCGCTGCCGCACGACCTTTTCACACCCCTTCACCGCCTGGAGCGTGTCCACCTGAACCACAACCCCTGGCACTGCAACTG
TGATGTGCTCTGGCTCAGCTGGTGGCTGAAGGAGACAGTGCCCAGCAATACCACATGCTGCGCACGCTGCCACGCGCCCGCCGGCCTCAAGGGCCGCTACATCGGTGAGCTGGACCAGTCGCACTTCA
CCTGCTATGCCCCAGTCATCGTGGAGCCACCCACAGACCTCAATGTCACCGAGGGCATGGCGGCCGAGCTCAAGTGCCGCACAGGTACATCCATGACCTCGGTCAACTGGCTGACACCTAACGGCACG
CTCATGACACACGGTTCCTATCGTGTGCGCATTTCGGTACTGCACGATGGCACACTCAATTTCACTAATGTCACCGTGCAGGACACGGGCCAGTACACGTGCATGGTGACAAACTCTGCTGGCAACAC
CACTGCCTCGGCCACGCTTAACGTGTCGGCCGTGGACCCTGTGGCTGCCGGAGGGCCCGGTGGCGGGGGCCCAGGGGGTGGGGGCGGTGCAGGGGGTGCGGGCGGCTACACCTACTTCACCACGGTGA
CTGTGGAGACGCTGGAGACACAGCCGGGGGAGGAGGCCCAGCAGCCCCGAGGTACTGAGAAGGAGCCCCCGGGGCCCACGACTGATGGCGCGTGGGGTGGCGGCCGGCCTGACGCTGCAGCCCCGGCC
TCAGCGTCCACCACGGCACCAGCCCCGCGCTCCTCGCGGCCCACAGAGAAGGCTTTCACGGTGCCCATCACGGACGTGACGGAGAACGCACTTAAGGACCTAGACGATGTCATGAAGACCACCAAAAT
CATCATCGGCTGCTTCGTGGCCATCACCTTTATGGCCGCCGTGATGCTGGTGGCCTTCTACAAGCTGCGCAAGCAGCACCAGCTGCACAAGCACCATGGGCCCACGCGCACTGTGGAGATCATCAACG
TGGAGGACGAGCTGCCCGCCGCCTCCGCTGTGTCGGTGGCTGCGGCCGCTGCGGTGGCTGGAGGCGCGGGCGTGGGTGGGGACAGCCACCTGGCTCTTCCGGCGCTGGAGCGAGACCACCTCAACCAC
CACCACTACGTGGCGGCTGCCTTCAAGGCGCACTACGGCGGCAATCCAGGAGGCGGGTGCGGGGCCAAGGGCCCCGGCCTCAACTCCATCCACGAACCTCTGCTCTTCAAGAGCGGCTCCAAGGAGAA
CGTGCAAGAGACACAAATCTAAACTTAGGCGCGCGGGGACGCGGGGACGCAGGACGCCTGCCCGAGATGCTCCTGCTTACCCAGCAGCCCTGGCGGCGCCTGCCTGTCCTGCAATGGGAAAGGACCTG
GAGATCAGGAGAGGTGGCCCCACCCTCCGCCTTGCCGTGTCCTCTGCCCACCTGCCCTGCCCGCCACCTTCCTGGGTTGAGGAGCTTCTTCGAGGGGTACCCTTTCCCCTCATCCCAACAACCCTTCT
TTTATGGCTCTTTCTTTTTTCTTTATTTCTTTGTTTTTTCCCCCTTTTGCAGTTTGACGCCTGTCCGTCCCTCCTACTCCACCACCCTCAAAACACAAGAGACAGACAACTTCACCAGAGCCCAGGGG
GCAACTCCGACAGTGTCCCCAACAGCGAGCTCCACTCGCGGCCCTGGCCGGCCCTACTCACCCCACAGACTCTTTTGATACTGAAGGGAGGTTTGCGTCAATCACTACCTGCTCTGTAATTACTTTAA
AAAAAAAAAAAAAAACACG

hide sequence


Protein RefSeqs	NP_001258010	(Get FASTA)	NCBI Sequence Viewer
	XP_006229117	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026259.5
GenBank Protein	P0CC10	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001258010 ⟸ NM_001271081
- Peptide Label:	precursor
- UniProtKB:	P0CC10 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAQAHIQGSPCPLLPPGRMSWPQGALLLLWLFSPPLRAGGGGVAVTSAAGGGSPPATSCPAACSCSNQASRVICTRRELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIE VGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTS LRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAE LKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGPGGGGPGGGGGAGGAGGYTYFTTVTVETLETQPGEEAQQPRGTEKEP PGPTTDGAWGGGRPDAAAPASASTTAPAPRSSRPTEKAFTVPITDVTENALKDLDDVMKTTKIIIGCFVAITFMAAVMLVAFYKLRKQHQLHKHHGPTRTVEIINVEDELPAASAVSVAAAAAVAGGA GVGGDSHLALPALERDHLNHHHYVAAAFKAHYGGNPGGGCGAKGPGLNSIHEPLLFKSGSKENVQETQI hide sequence

RefSeq Acc Id:	XP_006229117 ⟸ XM_006229055
- Peptide Label:	isoform X1
- UniProtKB:	P0CC10 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAQAHIQGSPCPLLPPGRMSWPQGALLLLWLFSPPLRAGGGGVAVTSAAGGGSPPATSCPAACSCSNQASRVICTRRELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIE VGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTS LRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAE LKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGPGGGGPGGGGGAGGAGGYTYFTTVTVETLETQPGEEAQQPRGTEKEP PGPTTDGAWGGGRPDAAAPASASTTAPAPRSSRPTEKAFTVPITDVTENALKDLDDVMKTTKIIIGCFVAITFMAAVMLVAFYKLRKQHQLHKHHGPTRTVEIINVEDELPAASAVSVAAAAAVAGGA GVGGDSHLALPALERDHLNHHHYVAAAFKAHYGGNPGGGCGAKGPGLNSIHEPLLFKSGSKENVQETQI hide sequence

Ensembl Acc Id:

ENSRNOP00000026259 ⟸ ENSRNOT00000026259

Protein Domains

Ig-like C2-type LRRCT LRRNT

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0CC10-F1-model_v2	AlphaFold	P0CC10	1-709	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-59772	BioCyc
Ensembl Genes	ENSRNOG00000019418	Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000026259.8	UniProtKB/Swiss-Prot
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
	3.80.10.10	UniProtKB/Swiss-Prot
InterPro	Cys-rich_flank_reg_C	UniProtKB/Swiss-Prot
	Ig-like_dom	UniProtKB/Swiss-Prot
	Ig-like_dom_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	Ig_I-set	UniProtKB/Swiss-Prot
	Ig_sub	UniProtKB/Swiss-Prot
	Ig_sub2	UniProtKB/Swiss-Prot
	Leu-rich_rpt	UniProtKB/Swiss-Prot
	Leu-rich_rpt_typical-subtyp	UniProtKB/Swiss-Prot
	LRR_dom_sf	UniProtKB/Swiss-Prot
	LRR_TM_domain-containing	UniProtKB/Swiss-Prot
	LRRNT	UniProtKB/Swiss-Prot
KEGG Report	rno:308571	UniProtKB/Swiss-Prot
NCBI Gene	308571	ENTREZGENE
PANTHER	ANTIGEN BSP, PUTATIVE-RELATED	UniProtKB/Swiss-Prot
	PTHR24369:SF102	UniProtKB/Swiss-Prot
Pfam	I-set	UniProtKB/Swiss-Prot
	LRR_1	UniProtKB/Swiss-Prot
	LRR_8	UniProtKB/Swiss-Prot
PhenoGen	Lrrc4b	PhenoGen
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot
	LRR	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000019418	RatGTEx
SMART	IGc2	UniProtKB/Swiss-Prot
	LRR_TYP	UniProtKB/Swiss-Prot
	LRRCT	UniProtKB/Swiss-Prot
	LRRNT	UniProtKB/Swiss-Prot
	SM00409	UniProtKB/Swiss-Prot
Superfamily-SCOP	L domain-like	UniProtKB/Swiss-Prot
	SSF48726	UniProtKB/Swiss-Prot
UniProt	LRC4B_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Lrrc4b	leucine rich repeat containing 4B	Lrrc4b_predicted	leucine rich repeat containing 4B (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Lrrc4b_predicted	leucine rich repeat containing 4B (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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