(-)-Arctigenin multiple interactions ISO Stat3 (Mus musculus) 6480464 arctigenin inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:21426947 (-)-Arctigenin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 arctigenin results in decreased phosphorylation of STAT3 protein CTD PMID:25380086 (-)-Arctigenin multiple interactions ISO STAT3 (Homo sapiens) 6480464 arctigenin inhibits the reaction [IL6 results in increased expression of STAT3 protein] and Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of STAT3 protein] CTD PMID:25100250 and PMID:25380086 (-)-cotinine increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Cotinine results in increased phosphorylation of STAT3 protein CTD PMID:31678612 (-)-demecolcine increases expression ISO STAT3 (Homo sapiens) 6480464 Demecolcine results in increased expression of STAT3 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate decreases expression ISO STAT3 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of STAT3 mRNA more ... CTD PMID:20816778 and PMID:22348037 (-)-epigallocatechin 3-gallate multiple interactions ISO STAT3 (Homo sapiens) 6480464 [docetaxel co-treated with epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:25655047 (-)-epigallocatechin 3-gallate decreases activity ISO STAT3 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased activity of STAT3 protein CTD PMID:22348037 (-)-lobeline multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Lobeline binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] and Lobeline inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 and PMID:20106947 (-)-matairesinol multiple interactions ISO STAT3 (Homo sapiens) 6480464 matairesinol inhibits the reaction [IL6 results in increased expression of STAT3 protein] CTD PMID:25100250 (-)-selegiline multiple interactions ISO Stat3 (Mus musculus) 6480464 [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 (20R)-protopanaxadiol affects expression ISO STAT3 (Homo sapiens) 6480464 protopanaxadiol affects the expression of STAT3 protein CTD PMID:31805304 (25R)-cholest-5-ene-3beta,26-diol multiple interactions ISO Stat3 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:28739487 (25R)-cholest-5-ene-3beta,26-diol increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:27856279 (25R)-cholest-5-ene-3beta,26-diol multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:27856279 (25R)-cholest-5-ene-3beta,26-diol increases phosphorylation ISO Stat3 (Mus musculus) 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:28739487 (R)-lipoic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:19635391 and PMID:28086195 (R)-noradrenaline increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Norepinephrine results in increased phosphorylation of STAT3 protein CTD PMID:34609854 (R)-noradrenaline multiple interactions ISO Stat3 (Mus musculus) 6480464 [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] and Carnosine inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 (R,R,R)-alpha-tocopherol increases expression EXP 6480464 alpha-Tocopherol results in increased expression of STAT3 mRNA CTD PMID:16908007 (S)-colchicine multiple interactions EXP 6480464 Colchicine promotes the reaction [Uric Acid results in increased phosphorylation of STAT3 protein] CTD PMID:33894285 (S)-naringenin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 naringenin results in decreased phosphorylation of STAT3 protein CTD PMID:27468969 (S)-nicotine multiple interactions ISO STAT3 (Homo sapiens) 6480464 [alpha-cyano-(3 more ... CTD PMID:18448488 more ... (S)-nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:34153408 (S)-nicotine affects expression EXP 6480464 Nicotine affects the expression of STAT3 mRNA CTD PMID:29155039 (S)-nicotine multiple interactions EXP 6480464 [Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form more ... CTD PMID:29501575 and PMID:34153408 (S)-nicotine increases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 results in increased susceptibility to Nicotine CTD PMID:20943775 (S)-nicotine increases activity ISO STAT3 (Homo sapiens) 6480464 Nicotine results in increased activity of STAT3 protein CTD PMID:18448488 (S)-nicotine increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:18448488 and PMID:35131329 (S)-nicotine multiple interactions ISO Stat3 (Mus musculus) 6480464 HMOX1 protein promotes the reaction [Nicotine results in increased phosphorylation of STAT3 protein] more ... CTD PMID:24095726 and PMID:36868510 (S)-nicotine increases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein results in increased susceptibility to Nicotine CTD PMID:24095726 (S)-nicotine increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:24095726 and PMID:25396421 1,1'-azobis(N,N-dimethylformamide) affects localization ISO STAT3 (Homo sapiens) 6480464 Diamide affects the localization of STAT3 protein CTD PMID:10364193 1,10-phenanthroline multiple interactions ISO STAT3 (Homo sapiens) 6480464 1 and 10-phenanthroline inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] CTD PMID:10364193 1,2-dimethylhydrazine increases expression ISO Stat3 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of STAT3 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO Stat3 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of STAT3 mRNA] CTD PMID:22206623 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of STAT3 mRNA CTD PMID:21983209 and PMID:22841810 1,4-naphthoquinone multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:30871965 1,4-naphthoquinone decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 1 and 4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein CTD PMID:30871965 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions ISO STAT3 (Homo sapiens) 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Stat3 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:28801915 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of STAT3 mRNA CTD PMID:17522070 and PMID:30723492 1-naphthyl isothiocyanate increases phosphorylation ISO Stat3 (Mus musculus) 6480464 1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein CTD PMID:27853831 and PMID:36460194 1-naphthyl isothiocyanate multiple interactions ISO Stat3 (Mus musculus) 6480464 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxy-1 more ... CTD PMID:27853831 and PMID:36460194 1-naphthyl isothiocyanate increases expression ISO Stat3 (Mus musculus) 6480464 1-Naphthylisothiocyanate results in increased expression of STAT3 mRNA CTD PMID:15913567 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO Stat3 (Mus musculus) 6480464 15-deoxy-delta(12 more ... CTD PMID:19922793 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein] CTD PMID:12584205 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO STAT3 (Homo sapiens) 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:12847270 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of STAT3 mRNA CTD PMID:16174780 17beta-estradiol multiple interactions ISO Stat3 (Mus musculus) 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of STAT3 mRNA] CTD PMID:25210133 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of STAT3 mRNA CTD PMID:32145629 17beta-estradiol increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Estradiol results in increased phosphorylation of STAT3 protein CTD PMID:17336289 17beta-estradiol multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:14975756 and PMID:17336289 17beta-estradiol increases expression ISO Stat3 (Mus musculus) 6480464 Estradiol results in increased expression of STAT3 mRNA CTD PMID:15289156 more ... 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Stat3 (Mus musculus) 6480464 [2 more ... CTD PMID:24978599 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Stat3 (Mus musculus) 6480464 2 more ... CTD PMID:30294300 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Stat3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of STAT3 mRNA CTD PMID:14708085 and PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of STAT3 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Stat3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of STAT3 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Stat3 (Mus musculus) 6480464 [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of STAT3 protein] more ... CTD PMID:14708085 and PMID:23639249 2,4,6-trinitrobenzenesulfonic acid increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein CTD PMID:25740948 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] more ... CTD PMID:30365937 and PMID:33522063 2,4,6-trinitrobenzenesulfonic acid increases phosphorylation EXP 6480464 Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein CTD PMID:30365937 and PMID:33522063 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:25740948 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of STAT3 mRNA CTD PMID:21346803 2,6-dichloroindophenol multiple interactions ISO STAT3 (Homo sapiens) 6480464 2 and 6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] CTD PMID:19635391 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of STAT3 mRNA CTD PMID:21346803 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein] and Verapamil inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] CTD PMID:19299911 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases phosphorylation EXP 6480464 4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of STAT3 protein CTD PMID:31231976 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions EXP 6480464 rhyncophylline inhibits the reaction [4-iodo-2 more ... CTD PMID:31231976 2-acetamidofluorene multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein and Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Stat3 (Mus musculus) 6480464 [Galactosamine co-treated with lipopolysaccharide more ... CTD PMID:28887131 2-butoxyethanol increases expression ISO Stat3 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of STAT3 mRNA CTD PMID:19812364 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of STAT3 mRNA CTD PMID:19643169 2-methylcholine affects expression ISO STAT3 (Homo sapiens) 6480464 beta-methylcholine affects the expression of STAT3 mRNA CTD PMID:21179406 25-hydroxycholesterol multiple interactions EXP 6480464 25-hydroxycholesterol inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:27052460 26-hydroxycholesterol multiple interactions ISO Stat3 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:28739487 26-hydroxycholesterol multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:27856279 26-hydroxycholesterol increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:27856279 26-hydroxycholesterol increases phosphorylation ISO Stat3 (Mus musculus) 6480464 27-hydroxycholesterol results in increased phosphorylation of STAT3 protein CTD PMID:28739487 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [3 more ... CTD PMID:28284859 3,3',4,4',5-pentachlorobiphenyl increases expression ISO STAT3 (Homo sapiens) 6480464 3 more ... CTD PMID:28284859 3,3',5,5'-tetraiodothyroacetic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 [heteronemin co-treated with tetraiodothyroacetic acid] results in decreased expression of STAT3 protein CTD PMID:35151786 3,3',5,5'-tetraiodothyroacetic acid decreases expression ISO STAT3 (Homo sapiens) 6480464 tetraiodothyroacetic acid results in decreased expression of STAT3 protein modified form CTD PMID:35151786 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions ISO Stat3 (Mus musculus) 6480464 cucurbitacin B inhibits the reaction [3 more ... CTD PMID:38104874 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO Stat3 (Mus musculus) 6480464 3 more ... CTD PMID:38104874 3-(1H-indol-3-yl)propanoic acid multiple interactions ISO STAT3 (Homo sapiens) 401793752 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression and increases phosphorylation of Stat3] in HK-2 human kidney proximal tubule cell line RGD 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO Stat3 (Mus musculus) 6480464 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]] and bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:24496235 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO STAT3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 3-methylcholanthrene multiple interactions ISO Stat3 (Mus musculus) 6480464 [Methylcholanthrene co-treated with Nanotubes and Carbon] results in decreased expression of STAT3 mRNA CTD PMID:25926378 3-Nitrobenzanthrone multiple interactions ISO STAT3 (Homo sapiens) 6480464 EREG protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein] and IL6 protein affects the reaction [3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein] CTD PMID:34036453 3-Nitrobenzanthrone increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 3-nitrobenzanthrone results in increased phosphorylation of STAT3 protein CTD PMID:34036453 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of STAT3 protein modified form] and cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:32628957 and PMID:33522063 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of STAT3 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol increases expression ISO STAT3 (Homo sapiens) 6480464 bisphenol S results in increased expression of STAT3 protein CTD PMID:34186270 4-hydroxynon-2-enal decreases expression ISO Stat3 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in decreased expression of STAT3 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO Stat3 (Mus musculus) 6480464 Fenretinide results in increased expression of STAT3 mRNA CTD PMID:28973697 4-nitrophenol increases expression ISO Stat3 (Mus musculus) 6480464 4-nitrophenol results in increased expression of STAT3 mRNA CTD PMID:34673133 4-tert-Octylphenol increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of STAT3 protein CTD PMID:32466334 5,6,7-trimethoxyflavone multiple interactions ISO Stat3 (Mus musculus) 6480464 5 more ... CTD PMID:24161485 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions ISO STAT3 (Homo sapiens) 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 5-aza-2'-deoxycytidine decreases expression ISO STAT3 (Homo sapiens) 6480464 Decitabine results in decreased expression of STAT3 protein CTD PMID:19732952 5-aza-2'-deoxycytidine multiple interactions ISO Stat3 (Mus musculus) 6480464 Decitabine inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased phosphorylation of STAT3 protein] CTD PMID:24440346 5-azacytidine multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein CTD PMID:18443271 5-fluorouracil increases expression ISO STAT3 (Homo sapiens) 6480464 Fluorouracil results in increased expression of STAT3 mRNA CTD PMID:16557594 5-fluorouracil affects response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 protein affects the susceptibility to Fluorouracil CTD PMID:15682485 and PMID:15730734 5-fluorouracil decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Fluorouracil results in decreased phosphorylation of STAT3 protein CTD PMID:18161298 and PMID:18205257 5-formyltetrahydrofolic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 FOLR1 protein affects the reaction [Leucovorin results in increased phosphorylation of STAT3 protein] more ... CTD PMID:25841994 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO STAT3 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:24064760 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:31981641 7,8-dihydroxycoumarin multiple interactions ISO STAT3 (Homo sapiens) 6480464 alpha-cyano-(3 more ... CTD PMID:37209277 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 Colchicine promotes the reaction [Uric Acid results in increased phosphorylation of STAT3 protein] and simiaowan promotes the reaction [Uric Acid results in increased phosphorylation of STAT3 protein] CTD PMID:33894285 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases phosphorylation EXP 6480464 Uric Acid results in increased phosphorylation of STAT3 protein CTD PMID:33894285 abamectin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of STAT3 mRNA] CTD PMID:34748272 abamectin increases expression EXP 6480464 abamectin results in increased expression of STAT3 mRNA CTD PMID:34748272 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of STAT3 mRNA CTD PMID:31881176 acetic acid increases phosphorylation EXP 6480464 Acetic Acid results in increased phosphorylation of STAT3 protein CTD PMID:35122774 acetic acid multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein] and Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:35122774 acetylsalicylic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 IL6 protein inhibits the reaction [Aspirin results in decreased expression of STAT3 protein modified form] CTD PMID:19595669 acetylsalicylic acid decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Aspirin results in decreased phosphorylation of STAT3 protein CTD PMID:20886344 acetylsalicylic acid decreases expression ISO STAT3 (Homo sapiens) 6480464 Aspirin results in decreased expression of STAT3 mRNA and Aspirin results in decreased expression of STAT3 protein modified form CTD PMID:11906190 and PMID:19595669 aflatoxin B1 increases expression ISO STAT3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of STAT3 mRNA CTD PMID:21641981 and PMID:28943387 Aflatoxin G1 increases phosphorylation ISO Stat3 (Mus musculus) 6480464 aflatoxin G1 results in increased phosphorylation of STAT3 protein CTD PMID:25445582 aldehydo-D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 and PMID:24810525 aldehydo-D-glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of STAT3 protein CTD PMID:24810525 aldehydo-D-glucose increases expression ISO STAT3 (Homo sapiens) 6480464 Glucose results in increased expression of STAT3 protein and Glucose results in increased expression of STAT3 protein modified form CTD PMID:24064760 aldehydo-D-glucose multiple interactions ISO STAT3 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:24064760 aldehydo-D-glucose multiple interactions ISO Stat3 (Mus musculus) 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 and PMID:26064446 all-trans-acitretin decreases expression ISO STAT3 (Homo sapiens) 6480464 Acitretin results in decreased expression of STAT3 mRNA more ... CTD PMID:16610086 all-trans-retinoic acid affects localization ISO Stat3 (Mus musculus) 6480464 Tretinoin affects the localization of STAT3 protein CTD PMID:17026715 all-trans-retinoic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 U 0126 inhibits the reaction [Tretinoin affects the localization of STAT3 protein] CTD PMID:17026715 all-trans-retinol affects expression EXP 6480464 Vitamin A affects the expression of STAT3 protein CTD PMID:15963505 allopurinol multiple interactions EXP 6480464 Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]] CTD PMID:21912612 Allylamine increases expression EXP 6480464 Allylamine results in increased expression of STAT3 protein CTD PMID:29355689 alpinumisoflavone multiple interactions ISO STAT3 (Homo sapiens) 6480464 alpinumisoflavone results in decreased phosphorylation of and results in decreased activity of STAT3 protein CTD PMID:23850732 aluminium hydroxide multiple interactions ISO Stat3 (Mus musculus) 6480464 [Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of STAT3 protein and nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of STAT3 protein] CTD PMID:36029577 alvocidib multiple interactions ISO STAT3 (Homo sapiens) 6480464 [alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein CTD PMID:15039284 alvocidib decreases expression ISO STAT3 (Homo sapiens) 6480464 alvocidib results in decreased expression of STAT3 mRNA CTD PMID:21239698 AM-251 decreases expression ISO STAT3 (Homo sapiens) 6480464 AM 251 results in decreased expression of STAT3 mRNA CTD PMID:16500647 AM-251 multiple interactions ISO STAT3 (Homo sapiens) 6480464 AM 251 inhibits the reaction [Cannabidiol results in increased phosphorylation of STAT3 protein] CTD PMID:33817834 AM-251 multiple interactions ISO Stat3 (Mus musculus) 6480464 AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:27071101 amidotrizoic acid affects expression ISO STAT3 (Homo sapiens) 6480464 Diatrizoate affects the expression of STAT3 protein modified form CTD PMID:21036957 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of STAT3 mRNA CTD PMID:16483693 amosite asbestos increases expression EXP 6480464 Asbestos and Amosite results in increased expression of STAT3 protein modified form CTD PMID:27083413 amosite asbestos increases activity ISO Stat3 (Mus musculus) 6480464 Asbestos and Amosite results in increased activity of STAT3 protein CTD PMID:29112861 amosite asbestos increases expression ISO Stat3 (Mus musculus) 6480464 Asbestos and Amosite results in increased expression of STAT3 mRNA CTD PMID:29112861 amphibole asbestos increases expression EXP 6480464 Asbestos and Amphibole results in increased expression of STAT3 protein modified form CTD PMID:27083413 andrographolide decreases activity ISO STAT3 (Homo sapiens) 6480464 andrographolide results in decreased activity of STAT3 protein CTD PMID:23845849 andrographolide multiple interactions ISO STAT3 (Homo sapiens) 6480464 andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of STAT3 protein] and IL6 protein promotes the reaction [andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of STAT3 protein]] CTD PMID:31128153 andrographolide multiple interactions ISO Stat3 (Mus musculus) 6480464 andrographolide inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of STAT3 protein] CTD PMID:31128153 Anemoside B4 decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 anemoside B4 results in decreased phosphorylation of STAT3 protein CTD PMID:36084722 Angoline multiple interactions ISO Stat3 (Mus musculus) 6480464 angoline inhibits the reaction [monobutyl phthalate results in increased expression of STAT3 mRNA] CTD PMID:37121744 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO STAT3 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [1 more ... CTD PMID:19429262 more ... anthra[1,9-cd]pyrazol-6(2H)-one increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 pyrazolanthrone results in increased phosphorylation of STAT3 protein CTD PMID:33030807 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:27174766 antigen multiple interactions ISO Stat3 (Mus musculus) 6480464 [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT3 mRNA CTD PMID:28935500 antirheumatic drug decreases expression ISO STAT3 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of STAT3 mRNA CTD PMID:24449571 apigenin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Apigenin results in decreased phosphorylation of STAT3 protein CTD PMID:27468969 apigenin multiple interactions ISO STAT3 (Homo sapiens) 6480464 Apigenin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein] CTD PMID:20153296 arecoline increases expression EXP 6480464 Arecoline results in increased expression of STAT3 protein CTD PMID:34999050 aristolochic acid A increases expression ISO STAT3 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of STAT3 mRNA CTD PMID:33212167 arsane decreases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 results in decreased susceptibility to Arsenic CTD PMID:15116095 arsane affects phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:35031324 arsane decreases expression ISO STAT3 (Homo sapiens) 6480464 Arsenic results in decreased expression of STAT3 mRNA CTD PMID:35031324 arsane increases expression ISO STAT3 (Homo sapiens) 6480464 Arsenic results in increased expression of STAT3 mRNA CTD PMID:27838757 arsane affects phosphorylation ISO Stat3 (Mus musculus) 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:27289040 arsane affects methylation ISO STAT3 (Homo sapiens) 6480464 Arsenic affects the methylation of STAT3 gene CTD PMID:25304211 arsane multiple interactions ISO STAT3 (Homo sapiens) 6480464 [ATF3 protein affects the susceptibility to Arsenic] which affects the phosphorylation of STAT3 protein more ... CTD PMID:24582688 more ... arsane increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic analog results in increased phosphorylation of STAT3 protein and Arsenic results in increased phosphorylation of STAT3 protein CTD PMID:24582688 and PMID:25559853 arsenic atom decreases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 results in decreased susceptibility to Arsenic CTD PMID:15116095 arsenic atom affects phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:35031324 arsenic atom decreases expression ISO STAT3 (Homo sapiens) 6480464 Arsenic results in decreased expression of STAT3 mRNA CTD PMID:35031324 arsenic atom increases expression ISO STAT3 (Homo sapiens) 6480464 Arsenic results in increased expression of STAT3 mRNA CTD PMID:27838757 arsenic atom affects phosphorylation ISO Stat3 (Mus musculus) 6480464 Arsenic affects the phosphorylation of STAT3 protein CTD PMID:27289040 arsenic atom affects methylation ISO STAT3 (Homo sapiens) 6480464 Arsenic affects the methylation of STAT3 gene CTD PMID:25304211 arsenic atom multiple interactions ISO STAT3 (Homo sapiens) 6480464 [ATF3 protein affects the susceptibility to Arsenic] which affects the phosphorylation of STAT3 protein more ... CTD PMID:24582688 more ... arsenic atom increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic analog results in increased phosphorylation of STAT3 protein and Arsenic results in increased phosphorylation of STAT3 protein CTD PMID:24582688 and PMID:25559853 arsenic trichloride increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 arsenic trichloride results in increased phosphorylation of STAT3 protein CTD PMID:22696236 arsenic trichloride affects phosphorylation ISO STAT3 (Homo sapiens) 6480464 arsenic trichloride affects the phosphorylation of STAT3 protein CTD PMID:24434654 arsenic trichloride multiple interactions ISO Stat3 (Mus musculus) 6480464 MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] and MAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] CTD PMID:22696236 arsenic trichloride multiple interactions ISO STAT3 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] more ... CTD PMID:22696236 and PMID:24434654 arsenite(3-) multiple interactions ISO STAT3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased phosphorylation of STAT3 protein more ... CTD PMID:24004609 arsenite(3-) increases expression ISO Stat3 (Mus musculus) 6480464 arsenite results in increased expression of STAT3 mRNA CTD PMID:18191166 arsenous acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Arsenic Trioxide results in decreased activity of NOTCH1 protein] which results in decreased phosphorylation of and results in decreased activity of STAT3 protein more ... CTD PMID:12492118 more ... arsenous acid affects localization ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide affects the localization of STAT3 protein CTD PMID:34108876 arsenous acid decreases expression ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of STAT3 mRNA and Arsenic Trioxide results in decreased expression of STAT3 protein CTD PMID:23382965 and PMID:34108876 arsenous acid decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:28454374 arsenous acid multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and affects the localization of STAT3 protein] more ... CTD PMID:27174766 arsenous acid affects methylation ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide affects the methylation of STAT3 promoter CTD PMID:26046465 arsenous acid increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of STAT3 protein CTD PMID:29396848 arsenous acid decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:25196641 more ... aspartame multiple interactions ISO Stat3 (Mus musculus) 6480464 [Fats and Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of STAT3 mRNA CTD PMID:23783067 atrazine multiple interactions ISO STAT3 (Homo sapiens) 6480464 Atrazine results in increased expression of and results in increased phosphorylation of STAT3 protein CTD PMID:34435054 aucubin multiple interactions ISO Stat3 (Mus musculus) 6480464 aucubin inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:32504734 auranofin decreases expression ISO STAT3 (Homo sapiens) 6480464 Auranofin results in decreased expression of STAT3 protein modified form CTD PMID:20542334 auranofin multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein CTD PMID:20542334 azathioprine multiple interactions ISO STAT3 (Homo sapiens) 6480464 Azathioprine inhibits the reaction [RAC1 protein binds to STAT3 protein] CTD PMID:12697733 baicalein multiple interactions ISO STAT3 (Homo sapiens) 6480464 baicalein inhibits the reaction [TGFB1 protein results in increased phosphorylation of STAT3 protein] CTD PMID:30201452 Bardoxolone methyl decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 bardoxolone methyl results in decreased phosphorylation of STAT3 protein CTD PMID:17363558 Bardoxolone methyl multiple interactions ISO Stat3 (Mus musculus) 6480464 [bardoxolone methyl co-treated with Dietary Fats] results in decreased expression of STAT3 protein and bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of STAT3 protein] CTD PMID:25637688 and PMID:27417254 bazedoxifene multiple interactions ISO STAT3 (Homo sapiens) 6480464 bazedoxifene inhibits the reaction [IL4 protein results in increased phosphorylation of STAT3 protein] CTD PMID:24456369 bazedoxifene decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 bazedoxifene results in decreased phosphorylation of STAT3 protein CTD PMID:24456369 bellidifolin decreases expression ISO STAT3 (Homo sapiens) 6480464 bellidifolin results in decreased expression of STAT3 mRNA CTD PMID:33299414 bellidifolin multiple interactions ISO STAT3 (Homo sapiens) 6480464 bellidifolin results in decreased expression of and results in decreased phosphorylation of STAT3 protein CTD PMID:33299414 benzatropine multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 benzo[a]pyrene affects activity ISO STAT3 (Homo sapiens) 6480464 Benzo(a)pyrene affects the activity of STAT3 protein CTD PMID:20624995 benzo[a]pyrene decreases methylation ISO STAT3 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of STAT3 promoter CTD PMID:27901495 benzo[a]pyrene affects methylation ISO STAT3 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of STAT3 5' UTR and Benzo(a)pyrene affects the methylation of STAT3 intron CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene multiple interactions ISO STAT3 (Homo sapiens) 6480464 [AHR protein affects the susceptibility to Benzo(a)pyrene] which affects the phosphorylation of and affects the localization of STAT3 protein more ... CTD PMID:31748929 benzo[a]pyrene increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Benzo(a)pyrene results in increased phosphorylation of STAT3 protein CTD PMID:31748929 benzo[a]pyrene increases expression ISO Stat3 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of STAT3 mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression ISO Stat3 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of STAT3 mRNA CTD PMID:19770486 benzo[a]pyrene diol epoxide I affects expression ISO STAT3 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 benzo[e]pyrene increases methylation ISO STAT3 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of STAT3 intron CTD PMID:30157460 benzoates multiple interactions ISO STAT3 (Homo sapiens) 6480464 Benzoates analog inhibits the reaction [IL6 protein results in increased activity of STAT3 protein] CTD PMID:29472718 benzoic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 Benzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] more ... CTD PMID:26088127 benzoic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 Benzoic Acid analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:26088127 beraprost multiple interactions ISO Stat3 (Mus musculus) 6480464 beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide and E coli O55-B5] results in increased phosphorylation of STAT3 protein] CTD PMID:28887131 berberine multiple interactions EXP 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of STAT3 mRNA] CTD PMID:35121005 berberine multiple interactions ISO Stat3 (Mus musculus) 6480464 Berberine inhibits the reaction [Particulate Matter results in increased expression of STAT3 mRNA] CTD PMID:37839514 Bergenin multiple interactions EXP 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:30365937 beta-Elemonic acid decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 beta-elemonic acid results in decreased phosphorylation of STAT3 protein CTD PMID:33878321 betulinic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Betulinic Acid co-treated with Erlotinib Hydrochloride] results in decreased expression of STAT3 protein modified form CTD PMID:30136359 bis(2-chloroethyl) sulfide increases expression ISO Stat3 (Mus musculus) 6480464 Mustard Gas results in increased expression of STAT3 mRNA CTD PMID:18955075 bisphenol A increases expression ISO STAT3 (Homo sapiens) 6480464 bisphenol A results in increased expression of STAT3 mRNA and bisphenol A results in increased expression of STAT3 protein CTD PMID:21909620 more ... bisphenol A increases expression ISO Stat3 (Mus musculus) 6480464 bisphenol A results in increased expression of STAT3 mRNA CTD PMID:32156529 and PMID:32575098 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of STAT3 mRNA CTD PMID:30903817 bisphenol A increases phosphorylation ISO Stat3 (Mus musculus) 6480464 bisphenol A results in increased phosphorylation of STAT3 protein CTD PMID:30609183 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of STAT3 gene CTD PMID:28505145 bisphenol A multiple interactions EXP 6480464 Curcumin inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA] CTD PMID:25963729 bisphenol A affects methylation ISO Stat3 (Mus musculus) 6480464 bisphenol A affects the methylation of STAT3 gene and bisphenol A affects the methylation of STAT3 promoter CTD PMID:26542749 and PMID:27334623 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of STAT3 mRNA CTD PMID:25181051 and PMID:25963729 bisphenol A increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 bisphenol A results in increased phosphorylation of STAT3 protein CTD PMID:22343039 more ... bisphenol A multiple interactions ISO STAT3 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 more ... bisphenol A multiple interactions ISO Stat3 (Mus musculus) 6480464 [bisphenol A co-treated with Dietary Fats] results in increased expression of STAT3 mRNA more ... CTD PMID:16860915 more ... bisphenol A increases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 results in increased susceptibility to bisphenol A CTD PMID:21909620 Bisphenol A diglycidyl ether multiple interactions ISO Stat3 (Mus musculus) 6480464 2 more ... CTD PMID:19922793 Bisphenol B increases expression ISO STAT3 (Homo sapiens) 6480464 bisphenol B results in increased expression of STAT3 protein CTD PMID:34186270 bisphenol F multiple interactions ISO STAT3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 bisphenol F multiple interactions ISO Stat3 (Mus musculus) 6480464 alpha-cyano-(3 more ... CTD PMID:32044397 bisphenol F increases phosphorylation ISO Stat3 (Mus musculus) 6480464 4 and 4'-bisphenol F results in increased phosphorylation of STAT3 protein CTD PMID:32044397 bleomycin A2 multiple interactions ISO Stat3 (Mus musculus) 6480464 honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 bleomycin A2 increases expression ISO Stat3 (Mus musculus) 6480464 Bleomycin results in increased expression of STAT3 protein modified form CTD PMID:32032644 bortezomib multiple interactions ISO STAT3 (Homo sapiens) 6480464 [alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein more ... CTD PMID:15039284 more ... bortezomib multiple interactions EXP 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of STAT3 mRNA] CTD PMID:35121005 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of STAT3 mRNA CTD PMID:35121005 BQ 123 multiple interactions ISO Stat3 (Mus musculus) 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Oxygen results in increased phosphorylation of STAT3 protein] CTD PMID:25203536 bucladesine multiple interactions ISO Stat3 (Mus musculus) 6480464 STAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]] CTD PMID:26064446 butein multiple interactions ISO STAT3 (Homo sapiens) 6480464 butein affects the reaction [IL6 protein affects the phosphorylation of STAT3 protein] CTD PMID:35130734 butylated hydroxyanisole multiple interactions ISO STAT3 (Homo sapiens) 6480464 Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein] more ... CTD PMID:17028263 cadmium atom multiple interactions ISO STAT3 (Homo sapiens) 6480464 Cadmium inhibits the reaction [CNTF protein affects the localization of STAT3 protein] and Cadmium inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:16843830 cadmium atom multiple interactions ISO Stat3 (Mus musculus) 6480464 [ITPR3 mutant form results in increased susceptibility to Cadmium] which results in increased expression of STAT3 mRNA and Cadmium promotes the reaction [ITPR3 mutant form results in increased expression of STAT3 mRNA] CTD PMID:37047547 cadmium atom increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Cadmium results in increased phosphorylation of STAT3 protein CTD PMID:31154059 cadmium dichloride multiple interactions ISO STAT3 (Homo sapiens) 6480464 2 more ... CTD PMID:16843830 more ... cadmium dichloride decreases expression ISO Stat3 (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of STAT3 protein modified form CTD PMID:33813002 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of STAT3 mRNA CTD PMID:25993096 cadmium dichloride increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Cadmium Chloride results in increased phosphorylation of STAT3 protein CTD PMID:23948867 cadmium dichloride increases expression ISO Stat3 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of STAT3 mRNA CTD PMID:23948867 cadmium dichloride increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Cadmium Chloride results in increased phosphorylation of STAT3 protein CTD PMID:27634459 cadmium dichloride multiple interactions ISO Stat3 (Mus musculus) 6480464 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:23376140 and PMID:23948867 cadmium dichloride affects localization ISO STAT3 (Homo sapiens) 6480464 Cadmium Chloride affects the localization of STAT3 protein modified form CTD PMID:19429262 caffeine affects phosphorylation ISO STAT3 (Homo sapiens) 6480464 Caffeine affects the phosphorylation of STAT3 protein CTD PMID:35688186 calcitriol increases expression ISO Stat3 (Mus musculus) 6480464 Calcitriol results in increased expression of STAT3 CTD PMID:19603526 calyculin a multiple interactions ISO STAT3 (Homo sapiens) 6480464 [calyculin A co-treated with LIF protein] results in increased phosphorylation of STAT3 protein CTD PMID:22142222 camostat increases phosphorylation ISO Stat3 (Mus musculus) 6480464 camostat results in increased phosphorylation of STAT3 protein CTD PMID:25104499 cannabidiol multiple interactions ISO Stat3 (Mus musculus) 6480464 Cannabidiol inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:19910459 cannabidiol increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Cannabidiol results in increased phosphorylation of STAT3 protein CTD PMID:32060308 and PMID:33817834 cannabidiol decreases expression ISO STAT3 (Homo sapiens) 6480464 Cannabidiol results in decreased expression of STAT3 mRNA CTD PMID:27932991 and PMID:31801206 cannabidiol multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Cannabidiol co-treated with Dronabinol] results in increased phosphorylation of STAT3 protein more ... CTD PMID:30096889 more ... capillarisin multiple interactions ISO STAT3 (Homo sapiens) 6480464 capillarisin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:24333736 capillarisin affects localization ISO STAT3 (Homo sapiens) 6480464 capillarisin affects the localization of STAT3 protein CTD PMID:24333736 capsaicin multiple interactions ISO STAT3 (Homo sapiens) 6480464 Bortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein] more ... CTD PMID:17505005 capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of STAT3 protein CTD PMID:16788306 capsaicin multiple interactions EXP 6480464 Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] and SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein] CTD PMID:16788306 and PMID:19285962 capsaicin affects localization ISO STAT3 (Homo sapiens) 6480464 Capsaicin affects the localization of STAT3 protein CTD PMID:17505005 carbamazepine affects expression ISO STAT3 (Homo sapiens) 6480464 Carbamazepine affects the expression of STAT3 mRNA CTD PMID:24752500 carbidopa multiple interactions ISO STAT3 (Homo sapiens) 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] and Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 carbidopa multiple interactions ISO Stat3 (Mus musculus) 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] and Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 carbofuran increases expression EXP 6480464 Carbofuran results in increased expression of STAT3 mRNA CTD PMID:22240977 and PMID:28982980 carbon nanotube increases expression ISO Stat3 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 more ... carbon nanotube multiple interactions EXP 6480464 [Nanotubes and Carbon co-treated with Dibutyl Phthalate] results in increased expression of STAT3 mRNA CTD PMID:37967788 carbon nanotube multiple interactions ISO Stat3 (Mus musculus) 6480464 [Dibutyl Phthalate co-treated with Nanotubes more ... CTD PMID:25926378 and PMID:38285958 carbon nanotube increases activity ISO Stat3 (Mus musculus) 6480464 Nanotubes and Carbon results in increased activity of STAT3 protein CTD PMID:29112861 carbonyl cyanide p-trifluoromethoxyphenylhydrazone affects response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone CTD PMID:20224768 carnosine multiple interactions ISO Stat3 (Mus musculus) 6480464 Carnosine inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of STAT3 mRNA CTD PMID:18500788 celecoxib multiple interactions ISO Stat3 (Mus musculus) 6480464 [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein CTD PMID:21268125 ceritinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 ceritinib analog results in decreased expression of and results in decreased phosphorylation of STAT3 protein CTD PMID:35803438 ceruletide multiple interactions ISO Stat3 (Mus musculus) 6480464 (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein] more ... CTD PMID:26390243 and PMID:34423886 ceruletide increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Ceruletide results in increased phosphorylation of STAT3 protein CTD PMID:34423886 cetrorelix decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 cetrorelix results in decreased phosphorylation of STAT3 protein CTD PMID:21062912 CGP 52608 multiple interactions ISO STAT3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to STAT3 gene] CTD PMID:28238834 chitin multiple interactions ISO STAT3 (Homo sapiens) 6480464 [[Aptamers more ... CTD PMID:30041514 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of STAT3 mRNA CTD PMID:23125180 chromium(6+) multiple interactions ISO STAT3 (Homo sapiens) 6480464 chromium hexavalent ion promotes the reaction [STAT3 protein binds to MIR21 promoter] more ... CTD PMID:17078813 more ... chromium(6+) increases expression ISO STAT3 (Homo sapiens) 6480464 chromium hexavalent ion results in increased expression of STAT3 protein CTD PMID:25448439 chrysin multiple interactions EXP 6480464 chrysin inhibits the reaction [Cyclophosphamide results in increased phosphorylation of STAT3 protein] CTD PMID:37263553 ciglitazone multiple interactions ISO Stat3 (Mus musculus) 6480464 2 more ... CTD PMID:19922793 Cirsimarin multiple interactions ISO Stat3 (Mus musculus) 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein] CTD PMID:30053449 cisplatin decreases activity ISO STAT3 (Homo sapiens) 6480464 Cisplatin results in decreased activity of STAT3 protein CTD PMID:20106947 cisplatin decreases expression ISO Stat3 (Mus musculus) 6480464 Cisplatin results in decreased expression of STAT3 protein CTD PMID:37395757 cisplatin decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Cisplatin results in decreased phosphorylation of STAT3 protein CTD PMID:37395757 cisplatin increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Cisplatin results in increased phosphorylation of STAT3 protein CTD PMID:34560070 cisplatin affects response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 protein affects the susceptibility to Cisplatin CTD PMID:34656559 cisplatin increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Cisplatin results in increased phosphorylation of STAT3 protein CTD PMID:31306688 more ... cisplatin multiple interactions ISO Stat3 (Mus musculus) 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] more ... CTD PMID:31306688 more ... cisplatin increases expression ISO STAT3 (Homo sapiens) 6480464 Cisplatin results in increased expression of STAT3 mRNA CTD PMID:27392435 cisplatin decreases phosphorylation ISO STAT3 (Homo sapiens) 127284886 cisplatin decreases phosphorylation of STAT3 protein in stomach RGD cisplatin decreases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 protein results in decreased susceptibility to Cisplatin and STAT3 results in decreased susceptibility to Cisplatin CTD PMID:20106947 more ... cisplatin multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of STAT3 mRNA more ... CTD PMID:20106947 more ... cladribine increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Cladribine results in increased phosphorylation of STAT3 protein CTD PMID:21679466 clorgyline multiple interactions ISO Stat3 (Mus musculus) 6480464 [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 cobalt dichloride multiple interactions ISO STAT3 (Homo sapiens) 6480464 [cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter] binds to [APEX1 protein binds to CREBBP promoter]] more ... CTD PMID:15735682 cocaine increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Cocaine results in increased phosphorylation of STAT3 protein CTD PMID:29673861 cocaine multiple interactions ISO Stat3 (Mus musculus) 6480464 alpha-cyano-(3 more ... CTD PMID:29673861 columbamine multiple interactions ISO STAT3 (Homo sapiens) 6480464 columbamine inhibits the reaction [CSF2 protein results in increased phosphorylation of STAT3 protein] CTD PMID:23124089 copper atom multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of STAT3 protein CTD PMID:20931265 copper atom increases expression ISO STAT3 (Homo sapiens) 6480464 Copper results in increased expression of STAT3 mRNA CTD PMID:16391388 copper(0) multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of STAT3 protein CTD PMID:20931265 copper(0) increases expression ISO STAT3 (Homo sapiens) 6480464 Copper results in increased expression of STAT3 mRNA CTD PMID:16391388 copper(II) sulfate multiple interactions ISO STAT3 (Homo sapiens) 6480464 [ferrous sulfate co-treated with Copper Sulfate] promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] and Copper Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:10364193 and PMID:16896058 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of STAT3 protein CTD PMID:30431687 copper(II) sulfate multiple interactions EXP 6480464 Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] more ... CTD PMID:30431687 copper(II) sulfate increases expression ISO STAT3 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of STAT3 mRNA CTD PMID:19549813 cordycepin increases phosphorylation ISO Stat3 (Mus musculus) 6480464 cordycepin results in increased phosphorylation of STAT3 protein CTD PMID:32042022 cordycepin multiple interactions ISO Stat3 (Mus musculus) 6480464 alpha-cyano-(3 and 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [cordycepin results in increased phosphorylation of STAT3 protein] CTD PMID:32042022 corosolic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] and corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] CTD PMID:26513295 corticosterone multiple interactions ISO Stat3 (Mus musculus) 6480464 [Corticosterone co-treated with Isoflurophate] results in increased phosphorylation of STAT3 protein more ... CTD PMID:28500787 coumarin increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 coumarin results in increased phosphorylation of STAT3 protein CTD PMID:35688186 coumermycin A1 multiple interactions ISO Stat3 (Mus musculus) 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased phosphorylation of STAT3 protein]] and coumermycin inhibits the reaction [limonin inhibits the reaction [Ceruletide results in increased phosphorylation of STAT3 protein]] CTD PMID:34423886 coumermycin A1 increases phosphorylation ISO Stat3 (Mus musculus) 6480464 coumermycin results in increased phosphorylation of STAT3 protein CTD PMID:34423886 coumestrol decreases expression ISO STAT3 (Homo sapiens) 6480464 Coumestrol results in decreased expression of STAT3 mRNA CTD PMID:19167446 crizotinib decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 crizotinib results in decreased phosphorylation of STAT3 protein CTD PMID:22034911 more ... crizotinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 [[crizotinib results in decreased phosphorylation of MET protein] which results in increased expression of HGF protein] which results in increased phosphorylation of STAT3 protein and MET gene mutant form promotes the reaction [crizotinib results in decreased phosphorylation of STAT3 protein] CTD PMID:22683780 and PMID:22729845 crocin-1 multiple interactions ISO STAT3 (Homo sapiens) 6480464 crocin affects the expression of and affects the phosphorylation of STAT3 protein CTD PMID:32886819 Cryptotanshinone decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 cryptotanshinone results in decreased phosphorylation of STAT3 protein CTD PMID:28578322 crystal violet multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein] inhibits the reaction [STAT3 protein binds to SOX2 promoter] and Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:27373978 cucurbitacin B multiple interactions ISO Stat3 (Mus musculus) 6480464 [WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin B more ... CTD PMID:24316209 more ... cucurbitacin B multiple interactions ISO STAT3 (Homo sapiens) 6480464 cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of and results in increased phosphorylation of STAT3 mRNA] CTD PMID:38104874 cucurbitacin B affects response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein affects the susceptibility to cucurbitacin B CTD PMID:24316209 cucurbitacin I multiple interactions ISO STAT3 (Homo sapiens) 6480464 cucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:19153190 cucurbitacin I decreases activity ISO Stat3 (Mus musculus) 6480464 cucurbitacin I results in decreased activity of STAT3 protein CTD PMID:24316209 cucurbitacin I multiple interactions ISO Stat3 (Mus musculus) 6480464 [WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin I CTD PMID:24316209 cucurbitacin I affects response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein affects the susceptibility to cucurbitacin I CTD PMID:24316209 Cuprizon increases expression ISO Stat3 (Mus musculus) 6480464 Cuprizone results in increased expression of STAT3 protein modified form CTD PMID:29864483 Cuprizon multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of STAT3 mRNA CTD PMID:26577399 and PMID:27523638 Cuprizon multiple interactions ISO Stat3 (Mus musculus) 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of STAT3 protein modified form] CTD PMID:29864483 curcumin multiple interactions ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide promotes the reaction [Curcumin results in decreased expression of STAT3 protein] more ... CTD PMID:16959222 more ... curcumin multiple interactions ISO Stat3 (Mus musculus) 6480464 [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of STAT3 protein] CTD PMID:33617879 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of STAT3 mRNA CTD PMID:25963729 curcumin multiple interactions EXP 6480464 Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] more ... CTD PMID:25963729 and PMID:30431687 curcumin increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Curcumin results in increased phosphorylation of STAT3 protein CTD PMID:25822711 curcumin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Curcumin results in decreased phosphorylation of STAT3 protein CTD PMID:19383353 curcumin decreases expression ISO STAT3 (Homo sapiens) 6480464 Curcumin results in decreased expression of STAT3 mRNA and Curcumin results in decreased expression of STAT3 protein CTD PMID:16959222 more ... cyanidin cation multiple interactions EXP 6480464 cyanidin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of STAT3 protein] CTD PMID:32044269 cyanidin cation multiple interactions ISO Stat3 (Mus musculus) 6480464 [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein and cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:32044269 cyclophosphamide increases phosphorylation EXP 6480464 Cyclophosphamide results in increased phosphorylation of STAT3 protein CTD PMID:19625377 and PMID:37263553 cyclophosphamide decreases expression ISO Stat3 (Mus musculus) 6480464 Cyclophosphamide results in decreased expression of STAT3 mRNA CTD PMID:37853057 cyclophosphamide multiple interactions ISO Stat3 (Mus musculus) 6480464 ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of STAT3 mRNA] CTD PMID:37853057 cyclophosphamide multiple interactions EXP 6480464 chrysin inhibits the reaction [Cyclophosphamide results in increased phosphorylation of STAT3 protein] CTD PMID:37263553 cyclophosphamide decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Cyclophosphamide results in decreased phosphorylation of STAT3 protein CTD PMID:21880982 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein] and Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] CTD PMID:19299911 cyclosporin A increases expression ISO Stat3 (Mus musculus) 6480464 Cyclosporine results in increased expression of STAT3 protein CTD PMID:27585667 cyclosporin A increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Cyclosporine results in increased phosphorylation of STAT3 protein CTD PMID:22155090 and PMID:23958496 cyclosporin A multiple interactions ISO Stat3 (Mus musculus) 6480464 alpha-cyano-(3 more ... CTD PMID:22155090 more ... cyhalothrin increases phosphorylation EXP 6480464 cyhalothrin results in increased phosphorylation of STAT3 protein CTD PMID:37060950 cypermethrin multiple interactions EXP 6480464 Quercetin inhibits the reaction [cypermethrin results in increased expression of STAT3 mRNA] CTD PMID:35876585 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of STAT3 mRNA CTD PMID:35876585 cytochalasin D multiple interactions ISO STAT3 (Homo sapiens) 6480464 Cytochalasin D deficiency results in decreased activity of and affects the localization of STAT3 protein CTD PMID:28086195 D-glucose multiple interactions ISO Stat3 (Mus musculus) 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 and PMID:26064446 D-glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of STAT3 protein CTD PMID:24810525 D-glucose multiple interactions ISO STAT3 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:24064760 D-glucose increases expression ISO STAT3 (Homo sapiens) 6480464 Glucose results in increased expression of STAT3 protein and Glucose results in increased expression of STAT3 protein modified form CTD PMID:24064760 D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 and PMID:24810525 dapagliflozin multiple interactions EXP 6480464 dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of STAT3 protein] and STAT3 protein promotes the reaction [dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]] CTD PMID:35438302 dapagliflozin increases expression EXP 6480464 dapagliflozin results in increased expression of STAT3 protein CTD PMID:35438302 DDE decreases activity ISO STAT3 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased activity of STAT3 protein CTD PMID:27589886 DDT multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of and results in increased expression of STAT3 protein] more ... CTD PMID:24820114 DDT affects localization ISO STAT3 (Homo sapiens) 6480464 DDT affects the localization of STAT3 protein CTD PMID:24820114 deguelin increases activity ISO STAT3 (Homo sapiens) 6480464 deguelin metabolite results in increased activity of STAT3 protein and deguelin results in increased activity of STAT3 protein CTD PMID:19139008 delphinidin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 delphinidin results in decreased phosphorylation of STAT3 protein CTD PMID:33955636 deoxynivalenol multiple interactions ISO Stat3 (Mus musculus) 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 deoxynivalenol increases phosphorylation ISO Stat3 (Mus musculus) 6480464 deoxynivalenol results in increased phosphorylation of STAT3 protein CTD PMID:22454431 and PMID:36602574 deoxynivalenol increases expression ISO Stat3 (Mus musculus) 6480464 deoxynivalenol results in increased expression of STAT3 mRNA CTD PMID:22454431 desferrioxamine B multiple interactions EXP 6480464 Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] CTD PMID:30431687 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 dexamethasone multiple interactions ISO STAT3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 dextran sulfate multiple interactions EXP 6480464 [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein and Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein] CTD PMID:19028472 dextran sulfate increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Dextran Sulfate results in increased phosphorylation of STAT3 protein CTD PMID:31737179 more ... dextran sulfate increases expression ISO Stat3 (Mus musculus) 6480464 Dextran Sulfate results in increased expression of STAT3 protein CTD PMID:26074695 dextran sulfate multiple interactions ISO Stat3 (Mus musculus) 6480464 3 more ... CTD PMID:20155626 more ... diarsenic trioxide multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Arsenic Trioxide results in decreased activity of NOTCH1 protein] which results in decreased phosphorylation of and results in decreased activity of STAT3 protein more ... CTD PMID:12492118 more ... diarsenic trioxide affects localization ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide affects the localization of STAT3 protein CTD PMID:34108876 diarsenic trioxide decreases expression ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of STAT3 mRNA and Arsenic Trioxide results in decreased expression of STAT3 protein CTD PMID:23382965 and PMID:34108876 diarsenic trioxide decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:28454374 diarsenic trioxide increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of STAT3 protein CTD PMID:29396848 diarsenic trioxide multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and affects the localization of STAT3 protein] more ... CTD PMID:27174766 diarsenic trioxide decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased phosphorylation of STAT3 protein CTD PMID:25196641 more ... diarsenic trioxide affects methylation ISO STAT3 (Homo sapiens) 6480464 Arsenic Trioxide affects the methylation of STAT3 promoter CTD PMID:26046465 dibenziodolium multiple interactions ISO STAT3 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:19429262 and PMID:20523355 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of STAT3 mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions ISO Stat3 (Mus musculus) 6480464 [Dibutyl Phthalate co-treated with Nanotubes and Carbon] results in increased expression of STAT3 protein CTD PMID:38285958 dibutyl phthalate multiple interactions EXP 6480464 [Nanotubes and Carbon co-treated with Dibutyl Phthalate] results in increased expression of STAT3 mRNA CTD PMID:37967788 dibutyl phthalate increases expression ISO Stat3 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of STAT3 mRNA CTD PMID:17361019 and PMID:21266533 diclofenac increases expression ISO Stat3 (Mus musculus) 6480464 Diclofenac results in increased expression of STAT3 mRNA CTD PMID:22285467 and PMID:26934552 diclofenac affects expression ISO STAT3 (Homo sapiens) 6480464 Diclofenac affects the expression of STAT3 mRNA CTD PMID:24752500 diclofenac increases expression ISO STAT3 (Homo sapiens) 6480464 Diclofenac results in increased expression of STAT3 mRNA CTD PMID:23506792 Dictamnine decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 dictamnine results in decreased phosphorylation of STAT3 protein CTD PMID:34861243 diethylstilbestrol increases expression ISO Stat3 (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of STAT3 mRNA CTD PMID:15289156 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of STAT3 mRNA CTD PMID:37077353 digitoxin multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Digitoxin co-treated with Oxygen deficiency] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:34717917 Diisodecyl phthalate multiple interactions ISO Stat3 (Mus musculus) 6480464 diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein] and Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] CTD PMID:27871981 diisononyl phthalate increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 diisononyl phthalate results in increased phosphorylation of STAT3 protein CTD PMID:31154059 diisopropyl fluorophosphate multiple interactions ISO Stat3 (Mus musculus) 6480464 [Corticosterone co-treated with Isoflurophate] results in increased phosphorylation of STAT3 protein CTD PMID:28500787 dimethyl sulfoxide multiple interactions ISO STAT3 (Homo sapiens) 6480464 [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA CTD PMID:31265865 dimethylarsinic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA CTD PMID:23192986 dimethylarsinic acid multiple interactions EXP 6480464 Cacodylic Acid results in increased expression of and results in increased phosphorylation of STAT3 protein CTD PMID:32890875 dinitrogen oxide multiple interactions ISO Stat3 (Mus musculus) 6480464 Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein] CTD PMID:15748169 dinitrogen oxide multiple interactions ISO STAT3 (Homo sapiens) 6480464 Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:15748169 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 dioxygen multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Digitoxin co-treated with Oxygen deficiency] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:20153296 more ... dioxygen increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Oxygen deficiency results in increased phosphorylation of STAT3 protein and Oxygen results in increased phosphorylation of STAT3 protein CTD PMID:19587783 more ... dioxygen increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Oxygen results in increased phosphorylation of STAT3 protein CTD PMID:25203536 dioxygen multiple interactions ISO Stat3 (Mus musculus) 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 more ... diquat increases expression ISO Stat3 (Mus musculus) 6480464 Diquat results in increased expression of STAT3 mRNA CTD PMID:36851058 docebenone multiple interactions ISO Stat3 (Mus musculus) 6480464 2 more ... CTD PMID:25432964 doxorubicin increases expression ISO STAT3 (Homo sapiens) 6480464 Doxorubicin results in increased expression of STAT3 mRNA and Doxorubicin results in increased expression of STAT3 protein CTD PMID:16001973 and PMID:17920763 doxorubicin multiple interactions EXP 6480464 dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of STAT3 protein] and STAT3 protein promotes the reaction [dapagliflozin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]] CTD PMID:35438302 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of STAT3 protein CTD PMID:35438302 doxorubicin increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Doxorubicin results in increased phosphorylation of STAT3 protein CTD PMID:24812279 and PMID:34605108 doxorubicin decreases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein results in decreased susceptibility to Doxorubicin CTD PMID:11524388 doxorubicin increases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 gene mutant form results in increased susceptibility to Doxorubicin and STAT3 protein results in increased susceptibility to Doxorubicin CTD PMID:10618415 more ... doxorubicin multiple interactions ISO Stat3 (Mus musculus) 6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of STAT3 mRNA more ... CTD PMID:10618415 more ... doxorubicin decreases expression ISO Stat3 (Mus musculus) 6480464 Doxorubicin results in decreased expression of STAT3 mRNA CTD PMID:10618415 doxorubicin affects response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 protein affects the susceptibility to Doxorubicin CTD PMID:17920763 ellagic acid increases expression ISO STAT3 (Homo sapiens) 6480464 Ellagic Acid results in increased expression of STAT3 mRNA CTD PMID:12002526 ellagic acid decreases expression ISO STAT3 (Homo sapiens) 6480464 Ellagic Acid results in decreased expression of STAT3 mRNA CTD PMID:20816778 emodin multiple interactions ISO STAT3 (Homo sapiens) 6480464 Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:23848338 emodin affects localization ISO STAT3 (Homo sapiens) 6480464 Emodin affects the localization of STAT3 protein CTD PMID:23848338 enalapril multiple interactions EXP 6480464 Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA] and Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein] CTD PMID:19958114 endosulfan multiple interactions ISO STAT3 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of STAT3 mRNA CTD PMID:29391264 entinostat increases expression ISO STAT3 (Homo sapiens) 6480464 entinostat results in increased expression of STAT3 mRNA CTD PMID:27188386 enzalutamide multiple interactions ISO STAT3 (Homo sapiens) 6480464 enzalutamide promotes the reaction [Niclosamide results in decreased phosphorylation of and results in decreased activity of STAT3 protein] and Niclosamide inhibits the reaction [STAT3 protein results in decreased susceptibility to enzalutamide] CTD PMID:25970160 enzalutamide decreases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 protein results in decreased susceptibility to enzalutamide CTD PMID:25970160 enzyme inhibitor multiple interactions EXP 6480464 Enzyme Inhibitors inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 protein modified form] CTD PMID:24792324 epoxiconazole decreases expression ISO Stat3 (Mus musculus) 6480464 epoxiconazole results in decreased expression of STAT3 mRNA CTD PMID:35436446 eriocitrin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 eriocitrin results in decreased phosphorylation of STAT3 protein CTD PMID:34724282 erlotinib hydrochloride increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein CTD PMID:23894143 erlotinib hydrochloride decreases expression ISO STAT3 (Homo sapiens) 6480464 Erlotinib Hydrochloride results in decreased expression of STAT3 protein modified form CTD PMID:30136359 erlotinib hydrochloride increases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 mutant form results in increased susceptibility to Erlotinib Hydrochloride CTD PMID:23894143 erlotinib hydrochloride decreases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 mRNA results in decreased susceptibility to Erlotinib Hydrochloride CTD PMID:23125191 erlotinib hydrochloride multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Betulinic Acid co-treated with Erlotinib Hydrochloride] results in decreased expression of STAT3 protein modified form more ... CTD PMID:23894143 and PMID:30136359 erythromycin estolate increases expression EXP 6480464 Erythromycin Estolate results in increased expression of STAT3 mRNA CTD PMID:17522070 ethanol multiple interactions EXP 6480464 Ethanol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein] CTD PMID:20052772 ethanol affects splicing ISO Stat3 (Mus musculus) 6480464 Ethanol affects the splicing of STAT3 mRNA CTD PMID:30319688 ethosuximide multiple interactions EXP 6480464 Ethosuximide inhibits the reaction [APP protein modified form results in decreased expression of STAT3 mRNA] CTD PMID:26420483 ethosuximide increases expression EXP 6480464 Ethosuximide results in increased expression of STAT3 mRNA CTD PMID:26420483 ethyl methanesulfonate increases expression ISO STAT3 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of STAT3 mRNA CTD PMID:23649840 fisetin multiple interactions ISO STAT3 (Homo sapiens) 6480464 fisetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein] CTD PMID:20153296 fisetin decreases expression ISO STAT3 (Homo sapiens) 6480464 fisetin results in decreased expression of STAT3 protein CTD PMID:30802432 fluorescein 5-isothiocyanate increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein CTD PMID:27871981 fluorescein 5-isothiocyanate multiple interactions ISO Stat3 (Mus musculus) 6480464 diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein] and Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] CTD PMID:27871981 fluticasone multiple interactions ISO STAT3 (Homo sapiens) 6480464 Fluticasone inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein] and TNF protein inhibits the reaction [Fluticasone inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]] CTD PMID:31822346 folic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 alpha-cyano-(3 more ... CTD PMID:25841994 and PMID:29685624 folic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of STAT3 mRNA] CTD PMID:22206623 folic acid increases expression ISO Stat3 (Mus musculus) 6480464 Folic Acid results in increased expression of STAT3 mRNA CTD PMID:25629700 formaldehyde increases expression ISO STAT3 (Homo sapiens) 6480464 Formaldehyde results in increased expression of STAT3 mRNA CTD PMID:23649840 FR900359 affects phosphorylation ISO STAT3 (Homo sapiens) 6480464 FR900359 affects the phosphorylation of STAT3 protein CTD PMID:37730182 fraxetin decreases phosphorylation ISO STAT3 (Homo sapiens) 125097526 Fraxetin decreases phosphorylation of STAT3 protein in colorectum RGD fructose increases phosphorylation EXP 6480464 Fructose results in increased phosphorylation of STAT3 protein CTD PMID:22426011 fructose decreases phosphorylation EXP 6480464 Fructose results in decreased phosphorylation of STAT3 protein CTD PMID:23533474 fructose multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:22426011 and PMID:23533474 fulvestrant multiple interactions ISO Stat3 (Mus musculus) 6480464 Fulvestrant inhibits the reaction [4 and 4'-bisphenol F results in increased phosphorylation of STAT3 protein] CTD PMID:32044397 fulvestrant decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Fulvestrant results in decreased phosphorylation of STAT3 protein CTD PMID:32044397 fulvestrant multiple interactions ISO STAT3 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:28284859 more ... galangin multiple interactions ISO STAT3 (Homo sapiens) 6480464 galangin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein] CTD PMID:20153296 galaxolide increases expression ISO STAT3 (Homo sapiens) 6480464 galaxolide results in increased expression of STAT3 mRNA CTD PMID:34687775 galaxolide multiple interactions ISO STAT3 (Homo sapiens) 6480464 [galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of STAT3 mRNA CTD PMID:34687775 Galiellalactone decreases activity ISO STAT3 (Homo sapiens) 6480464 [galiellalactone results in decreased activity of STAT3 protein] which results in decreased activity of AR protein and galiellalactone results in decreased activity of STAT3 protein CTD PMID:30254184 Ganoderic acid A multiple interactions ISO Stat3 (Mus musculus) 6480464 ganoderic acid A inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein] CTD PMID:34029542 Ganoderic acid C2 multiple interactions ISO Stat3 (Mus musculus) 6480464 ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of STAT3 mRNA] CTD PMID:37853057 Garcinol decreases expression ISO STAT3 (Homo sapiens) 151667907 garcinol decreases expression of STAT3 protein in xenograft glioblastoma tumor RGD gefitinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 gefitinib inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] and gefitinib inhibits the reaction [EGF results in increased phosphorylation of STAT3 protein] CTD PMID:19318490 and PMID:21787763 gefitinib multiple interactions ISO Stat3 (Mus musculus) 6480464 gefitinib inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA] and gefitinib inhibits the reaction [Cadmium Chloride results in increased phosphorylation of STAT3 protein] CTD PMID:23948867 gemcitabine decreases activity ISO STAT3 (Homo sapiens) 6480464 Gemcitabine results in decreased activity of STAT3 protein CTD PMID:22348037 genistein increases expression ISO Stat3 (Mus musculus) 6480464 Genistein results in increased expression of STAT3 mRNA CTD PMID:15289156 genistein multiple interactions ISO STAT3 (Homo sapiens) 6480464 Genistein inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of STAT3 protein] and Genistein inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] CTD PMID:10364193 and PMID:33396024 genistein decreases expression ISO Stat3 (Mus musculus) 6480464 Genistein results in decreased expression of STAT3 mRNA CTD PMID:21048042 genistein decreases expression ISO STAT3 (Homo sapiens) 6480464 Genistein results in decreased expression of STAT3 mRNA CTD PMID:20816778 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of STAT3 mRNA CTD PMID:22061828 and PMID:33387578 Gingerenone A decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 gingerenone A results in decreased phosphorylation of STAT3 protein CTD PMID:26242912 and PMID:33050000 Ginkgoic acid decreases phosphorylation ISO STAT3 (Homo sapiens) 127284886 Ginkgoic acid decreases phosphorylation of STAT3 protein in stomach RGD glafenine increases expression EXP 6480464 Glafenine results in increased expression of STAT3 mRNA CTD PMID:24136188 glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA more ... CTD PMID:23421680 and PMID:24810525 glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of STAT3 protein CTD PMID:24810525 glucose increases expression ISO STAT3 (Homo sapiens) 6480464 Glucose results in increased expression of STAT3 protein and Glucose results in increased expression of STAT3 protein modified form CTD PMID:24064760 glucose multiple interactions ISO STAT3 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:24064760 glucose multiple interactions ISO Stat3 (Mus musculus) 6480464 [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21940958 and PMID:26064446 glutathione multiple interactions ISO STAT3 (Homo sapiens) 6480464 Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:16896058 glutathione affects abundance ISO Stat3 (Mus musculus) 6480464 STAT3 protein affects the abundance of Glutathione CTD PMID:20224768 Glutathione ethyl ester multiple interactions EXP 6480464 S-ethyl glutathione inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 mRNA] CTD PMID:24792324 glycine betaine multiple interactions EXP 6480464 Betaine promotes the reaction [Isoproterenol results in increased phosphorylation of STAT3 protein] CTD PMID:25080425 glyphosate decreases expression ISO STAT3 (Homo sapiens) 6480464 Glyphosate results in decreased expression of STAT3 mRNA CTD PMID:31295307 gold atom increases expression ISO Stat3 (Mus musculus) 6480464 Gold results in increased expression of STAT3 mRNA CTD PMID:22155353 gold atom multiple interactions ISO Stat3 (Mus musculus) 6480464 [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA CTD PMID:22155353 gold(0) increases expression ISO Stat3 (Mus musculus) 6480464 Gold results in increased expression of STAT3 mRNA CTD PMID:22155353 gold(0) multiple interactions ISO Stat3 (Mus musculus) 6480464 [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA CTD PMID:22155353 GSK690693 multiple interactions ISO STAT3 (Homo sapiens) 6480464 GSK690693 promotes the reaction [1 and 4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein] CTD PMID:30871965 GW 3965 multiple interactions EXP 6480464 GW 3965 inhibits the reaction [IL6 protein results in increased expression of STAT3 protein modified form] CTD PMID:27052460 halothane multiple interactions ISO Stat3 (Mus musculus) 6480464 Halothane results in increased expression of and results in increased phosphorylation of STAT3 protein CTD PMID:24598351 halothane increases expression ISO Stat3 (Mus musculus) 6480464 Halothane results in increased expression of STAT3 mRNA CTD PMID:24598351 hesperetin multiple interactions EXP 6480464 hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:33522063 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of STAT3 mRNA] CTD PMID:34748272 Hexachloro-1,3-butadiene increases expression EXP 6480464 hexachlorobutadiene results in increased expression of STAT3 mRNA CTD PMID:21905055 hexadecanoic acid decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Palmitic Acid results in decreased phosphorylation of STAT3 protein CTD PMID:28073184 Hexamethonium multiple interactions ISO STAT3 (Homo sapiens) 6480464 Hexamethonium inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 and PMID:20106947 Hexamethonium multiple interactions EXP 6480464 Hexamethonium inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form] CTD PMID:29501575 Honokiol multiple interactions ISO Stat3 (Mus musculus) 6480464 honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 Honokiol multiple interactions ISO STAT3 (Homo sapiens) 6480464 honokiol inhibits the reaction [TGFB1 protein results in increased expression of STAT3 protein modified form] CTD PMID:32032644 hydrogen peroxide multiple interactions ISO STAT3 (Homo sapiens) 6480464 1 more ... CTD PMID:10364193 more ... hydrogen peroxide increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased phosphorylation of STAT3 protein CTD PMID:17028263 hydrogen peroxide increases ubiquitination ISO STAT3 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased ubiquitination of STAT3 protein CTD PMID:24657799 hydrogen peroxide multiple interactions ISO Stat3 (Mus musculus) 6480464 Hydrogen Peroxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein] CTD PMID:15748169 hydroxamic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 Hydroxamic Acids analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] and Hydroxamic Acids analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein CTD PMID:26088127 hydroxamic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 Hydroxamic Acids analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] more ... CTD PMID:26088127 hydroxysafflor yellow A multiple interactions ISO Stat3 (Mus musculus) 6480464 hydroxysafflor yellow A inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:37195255 imiquimod increases expression ISO Stat3 (Mus musculus) 6480464 imiquimod results in increased expression of STAT3 mRNA CTD PMID:26149470 indometacin multiple interactions ISO Stat3 (Mus musculus) 6480464 [Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein more ... CTD PMID:21268125 indometacin multiple interactions ISO STAT3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA CTD PMID:28628672 indoxyl sulfate multiple interactions ISO Stat3 (Mus musculus) 6480464 [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of STAT3 protein] and Indican results in increased phosphorylation of and results in increased activity of STAT3 protein CTD PMID:23639249 indoxyl sulfate multiple interactions ISO STAT3 (Homo sapiens) 401793752 indoxyl sulfate increases expression and increases phosphorylation of Stat3 in HK-2 human kidney proximal tubule cell line RGD Interferon beta-1b multiple interactions ISO STAT3 (Homo sapiens) 6480464 6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside inhibits the reaction [Interferon beta-1b results in increased phosphorylation of STAT3 protein] CTD PMID:29031523 Interferon beta-1b increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Interferon beta-1b results in increased phosphorylation of STAT3 protein CTD PMID:29031523 iomeprol affects expression ISO STAT3 (Homo sapiens) 6480464 iomeprol affects the expression of STAT3 protein modified form CTD PMID:21036957 iron(2+) sulfate (anhydrous) multiple interactions ISO STAT3 (Homo sapiens) 6480464 [ferrous sulfate co-treated with Copper Sulfate] promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] CTD PMID:10364193 isoliquiritigenin multiple interactions ISO Stat3 (Mus musculus) 6480464 isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein] CTD PMID:25026504 isoorientin decreases expression ISO STAT3 (Homo sapiens) 6480464 homoorientin results in decreased expression of STAT3 protein modified form CTD PMID:34019859 isoorientin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 homoorientin results in decreased phosphorylation of STAT3 protein CTD PMID:34019859 isoprenaline affects localization EXP 6480464 Isoproterenol affects the localization of STAT3 protein CTD PMID:19299911 isoprenaline multiple interactions ISO Stat3 (Mus musculus) 6480464 STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]] CTD PMID:31712309 isoprenaline multiple interactions ISO STAT3 (Homo sapiens) 6480464 STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol] CTD PMID:31712309 isoprenaline increases phosphorylation EXP 6480464 Isoproterenol results in increased phosphorylation of STAT3 protein CTD PMID:25080425 isoprenaline increases expression ISO Stat3 (Mus musculus) 6480464 Isoproterenol results in increased expression of STAT3 mRNA CTD PMID:21335049 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of STAT3 and Isoproterenol results in increased expression of STAT3 protein CTD PMID:19299911 and PMID:29355689 isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT3 mRNA more ... CTD PMID:19299911 more ... ivermectin decreases expression ISO STAT3 (Homo sapiens) 6480464 Ivermectin results in decreased expression of STAT3 protein CTD PMID:32959892 ivermectin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Ivermectin results in decreased phosphorylation of STAT3 protein CTD PMID:34904774 ivermectin multiple interactions ISO STAT3 (Homo sapiens) 6480464 AZD 1480 inhibits the reaction [SLC2A4 protein inhibits the reaction [Ivermectin results in decreased phosphorylation of STAT3 protein]] and SLC2A4 protein inhibits the reaction [Ivermectin results in decreased phosphorylation of STAT3 protein] CTD PMID:34904774 ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of STAT3 mRNA CTD PMID:37077353 kurarinol multiple interactions ISO Stat3 (Mus musculus) 6480464 kurarinol inhibits the reaction [STAT3 protein binds to BCL2L1 promoter] CTD PMID:24997323 kurarinol decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 kurarinol results in decreased phosphorylation of STAT3 protein CTD PMID:24997323 kurarinol multiple interactions ISO STAT3 (Homo sapiens) 6480464 kurarinol inhibits the reaction [STAT3 protein binds to BCL2L1 promoter] and STAT3 protein inhibits the reaction [kurarinol results in increased activity of CASP3 protein] CTD PMID:24997323 kurarinol decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 kurarinol results in decreased phosphorylation of STAT3 protein CTD PMID:24997323 L-arginine multiple interactions ISO Stat3 (Mus musculus) 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:34423886 L-arginine increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Arginine results in increased phosphorylation of STAT3 protein CTD PMID:34423886 L-ascorbic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:16896058 L-ascorbic acid affects expression ISO STAT3 (Homo sapiens) 6480464 Ascorbic Acid affects the expression of STAT3 mRNA CTD PMID:30597948 L-mimosine increases phosphorylation EXP 6480464 Mimosine results in increased phosphorylation of STAT3 protein CTD PMID:25469848 lapatinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 Lapatinib inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of STAT3 protein]] and Lapatinib inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein] CTD PMID:32890875 and PMID:33396024 lead diacetate increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 lead acetate results in increased phosphorylation of STAT3 protein CTD PMID:26542248 lead(0) increases expression ISO Stat3 (Mus musculus) 6480464 Lead results in increased expression of STAT3 mRNA CTD PMID:35760230 leflunomide increases expression ISO STAT3 (Homo sapiens) 6480464 leflunomide results in increased expression of STAT3 mRNA CTD PMID:28988120 levofloxacin increases expression EXP 6480464 Levofloxacin results in increased expression of STAT3 mRNA CTD PMID:24136188 limonin multiple interactions ISO Stat3 (Mus musculus) 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:34423886 linagliptin multiple interactions ISO Stat3 (Mus musculus) 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of STAT3 protein modified form] CTD PMID:29864483 linagliptin multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:35122774 lipoic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:19635391 and PMID:28086195 lipopolysaccharide increases activity ISO STAT3 (Homo sapiens) 6480464 Lipopolysaccharides results in increased activity of STAT3 protein CTD PMID:21586572 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of STAT3 protein CTD PMID:35279615 lipopolysaccharide increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Lipopolysaccharides results in increased phosphorylation of STAT3 protein CTD PMID:32583487 and PMID:37209277 lipopolysaccharide increases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 gene mutant form results in increased susceptibility to Lipopolysaccharides and STAT3 results in increased susceptibility to Lipopolysaccharides CTD PMID:15781265 and PMID:25429137 lipopolysaccharide increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Lipopolysaccharides results in increased phosphorylation of STAT3 protein CTD PMID:21262334 more ... lipopolysaccharide increases expression ISO Stat3 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of STAT3 mRNA CTD PMID:10975854 more ... lipopolysaccharide increases activity ISO Stat3 (Mus musculus) 6480464 [Lipopolysaccharides results in increased activity of JAK2 protein] which results in increased activity of STAT3 protein and Lipopolysaccharides results in increased activity of STAT3 protein CTD PMID:21586572 more ... lipopolysaccharide multiple interactions ISO Stat3 (Mus musculus) 6480464 [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of STAT3 protein] more ... CTD PMID:16275627 more ... lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of STAT3 protein CTD PMID:12584205 lipopolysaccharide multiple interactions EXP 6480464 15-deoxy-delta(12 more ... CTD PMID:12584205 and PMID:35279615 lipopolysaccharide multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Nicotine co-treated with Lipopolysaccharides] results in increased phosphorylation of STAT3 protein more ... CTD PMID:21135123 more ... lipoxin A4 multiple interactions ISO Stat3 (Mus musculus) 6480464 lipoxin A4 inhibits the reaction [Ovalbumin results in increased phosphorylation of STAT3 protein] CTD PMID:34537180 lithium chloride multiple interactions ISO STAT3 (Homo sapiens) 6480464 Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 lithocholic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 cucurbitacin B inhibits the reaction [Lithocholic Acid results in increased expression of and results in increased phosphorylation of STAT3 mRNA] and Lithocholic Acid results in increased expression of and results in increased phosphorylation of STAT3 mRNA CTD PMID:38104874 loganin multiple interactions ISO Stat3 (Mus musculus) 6480464 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:35279615 loganin multiple interactions EXP 6480464 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of STAT3 protein] CTD PMID:35279615 loliolide multiple interactions ISO STAT3 (Homo sapiens) 6480464 loliolide inhibits the reaction [SOD2 protein results in increased phosphorylation of STAT3 protein] CTD PMID:36707041 losartan decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Losartan results in decreased phosphorylation of STAT3 protein CTD PMID:33380422 losartan decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Losartan results in decreased phosphorylation of STAT3 protein CTD PMID:33380422 luteolin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Luteolin results in decreased phosphorylation of STAT3 protein CTD PMID:24525192 luteolin multiple interactions ISO Stat3 (Mus musculus) 6480464 Luteolin inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:38103742 luteolin multiple interactions ISO STAT3 (Homo sapiens) 6480464 Luteolin inhibits the reaction [chromium hexavalent ion results in increased expression of STAT3 protein] more ... CTD PMID:24525192 and PMID:25448439 luteolin 7-O-beta-D-glucoside multiple interactions ISO STAT3 (Homo sapiens) 6480464 1 more ... CTD PMID:31381935 LY294002 multiple interactions ISO STAT3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IFNG protein results in decreased phosphorylation of STAT3 protein] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Silicon Dioxide results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:16427044 and PMID:29894800 LY294002 multiple interactions EXP 6480464 Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein] CTD PMID:34455488 LY294002 increases phosphorylation EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein CTD PMID:34455488 lycopene increases expression ISO STAT3 (Homo sapiens) 6480464 lycopene results in increased expression of STAT3 mRNA CTD PMID:16886892 lycorine multiple interactions ISO Stat3 (Mus musculus) 6480464 lycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein] CTD PMID:22155741 malaoxon decreases phosphorylation EXP 6480464 malaoxon results in decreased phosphorylation of STAT3 protein CTD PMID:34778934 malathion decreases phosphorylation EXP 6480464 Malathion results in decreased phosphorylation of STAT3 protein CTD PMID:34778934 maneb multiple interactions ISO Stat3 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA more ... CTD PMID:23963992 manganese atom multiple interactions ISO Stat3 (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein] and [manganese chloride results in increased abundance of Manganese] which affects the localization of STAT3 protein CTD PMID:34018660 manganese(0) multiple interactions ISO Stat3 (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein] and [manganese chloride results in increased abundance of Manganese] which affects the localization of STAT3 protein CTD PMID:34018660 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of STAT3 mRNA CTD PMID:28801915 manganese(II) chloride multiple interactions ISO Stat3 (Mus musculus) 6480464 [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein] and [manganese chloride results in increased abundance of Manganese] which affects the localization of STAT3 protein CTD PMID:34018660 manganese(II) chloride decreases expression ISO Stat3 (Mus musculus) 6480464 manganese chloride results in decreased expression of STAT3 mRNA CTD PMID:28801915 manganese(II) chloride increases methylation EXP 6480464 manganese chloride results in increased methylation of STAT3 gene CTD PMID:28801915 manumycin A multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [manumycin results in decreased phosphorylation of STAT3 protein] CTD PMID:19409983 manumycin A decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 manumycin results in decreased phosphorylation of STAT3 protein CTD PMID:19409983 maslinic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] and maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] CTD PMID:26513295 masoprocol decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Masoprocol results in decreased phosphorylation of STAT3 protein CTD PMID:19503098 melatonin multiple interactions ISO Stat3 (Mus musculus) 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA] more ... CTD PMID:22225513 more ... melatonin increases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein results in increased susceptibility to Melatonin CTD PMID:21342247 melatonin increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Melatonin results in increased phosphorylation of STAT3 protein CTD PMID:21342247 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein] CTD PMID:19028472 melittin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Melitten results in decreased phosphorylation of STAT3 protein CTD PMID:22027265 melittin multiple interactions EXP 6480464 Melitten inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased expression of STAT3 mRNA] and Melitten inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:21354845 melittin multiple interactions ISO STAT3 (Homo sapiens) 6480464 TNFRSF10A protein affects the reaction [Melitten results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:22027265 mercury dichloride multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:16896058 and PMID:19635391 mercury dichloride increases expression ISO Stat3 (Mus musculus) 6480464 Mercuric Chloride results in increased expression of STAT3 mRNA CTD PMID:37172713 mercury dichloride multiple interactions ISO Stat3 (Mus musculus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Mercuric Chloride results in increased phosphorylation of STAT3 protein] CTD PMID:29981841 mercury dichloride increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Mercuric Chloride analog results in increased phosphorylation of STAT3 protein and Mercuric Chloride results in increased phosphorylation of STAT3 protein CTD PMID:29981841 mesalamine multiple interactions EXP 6480464 Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:35122774 mesalamine multiple interactions ISO Stat3 (Mus musculus) 6480464 Mesalamine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein] CTD PMID:36543318 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of STAT3 mRNA CTD PMID:30467583 methapyrilene increases methylation ISO STAT3 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of STAT3 intron CTD PMID:30157460 methotrexate decreases expression ISO STAT3 (Homo sapiens) 6480464 Methotrexate results in decreased expression of STAT3 mRNA CTD PMID:24449571 methotrexate multiple interactions ISO STAT3 (Homo sapiens) 6480464 Methotrexate inhibits the reaction [Oncostatin M results in increased expression of STAT3 mRNA] CTD PMID:34953855 methoxychlor multiple interactions ISO STAT3 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 methyl methanesulfonate decreases expression ISO STAT3 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of STAT3 mRNA CTD PMID:23649840 methylarsonic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA CTD PMID:23192986 methylglyoxal increases phosphorylation EXP 6480464 Pyruvaldehyde results in increased phosphorylation of STAT3 protein CTD PMID:34455488 methylglyoxal multiple interactions EXP 6480464 Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of STAT3 protein] CTD PMID:34455488 methyllycaconitine multiple interactions ISO STAT3 (Homo sapiens) 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 methyllycaconitine multiple interactions EXP 6480464 methyllycaconitine inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form] CTD PMID:29501575 methyllycaconitine decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 methyllycaconitine results in decreased phosphorylation of STAT3 protein CTD PMID:25396421 methylmercury chloride increases expression ISO Stat3 (Mus musculus) 6480464 methylmercuric chloride results in increased expression of STAT3 mRNA CTD PMID:33338554 methylmercury chloride multiple interactions ISO Stat3 (Mus musculus) 6480464 methylmercuric chloride promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein] CTD PMID:33338554 Methylthiouracil multiple interactions ISO STAT3 (Homo sapiens) 6480464 Methylthiouracil inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein] CTD PMID:26298005 mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]] CTD PMID:16534557 mevalonic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT3 protein] CTD PMID:18453621 microcystin-LR increases phosphorylation ISO Stat3 (Mus musculus) 6480464 cyanoginosin LR results in increased phosphorylation of STAT3 protein CTD PMID:33474710 microcystin-LR multiple interactions ISO STAT3 (Homo sapiens) 6480464 cyanoginosin LR results in increased expression of and results in increased phosphorylation of STAT3 protein CTD PMID:36115647 microcystin-LR multiple interactions ISO Stat3 (Mus musculus) 6480464 cyanoginosin LR results in increased expression of and results in increased phosphorylation of STAT3 protein CTD PMID:36115647 mocetinostat increases acetylation ISO STAT3 (Homo sapiens) 6480464 mocetinostat results in increased acetylation of STAT3 protein CTD PMID:26775640 Monobutylphthalate increases expression ISO Stat3 (Mus musculus) 6480464 monobutyl phthalate results in increased expression of STAT3 mRNA CTD PMID:37121744 Monobutylphthalate multiple interactions ISO Stat3 (Mus musculus) 6480464 angoline inhibits the reaction [monobutyl phthalate results in increased expression of STAT3 mRNA] CTD PMID:37121744 monocrotaline multiple interactions EXP 6480464 [Monocrotaline co-treated with TGFB1] results in increased phosphorylation of STAT3 protein and NCP-2454 inhibits the reaction [Monocrotaline results in increased phosphorylation of STAT3 protein] CTD PMID:25275723 and PMID:27870162 monocrotaline increases phosphorylation EXP 6480464 Monocrotaline results in increased phosphorylation of STAT3 protein CTD PMID:25275723 monosodium L-glutamate multiple interactions ISO Stat3 (Mus musculus) 6480464 [Fats and Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of STAT3 mRNA CTD PMID:23783067 monosodium L-glutamate decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Sodium Glutamate results in decreased phosphorylation of STAT3 protein CTD PMID:24502529 morphine increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Morphine results in increased phosphorylation of STAT3 protein CTD PMID:18385270 Morroniside multiple interactions EXP 6480464 morroniside inhibits the reaction [Lipopolysaccharides results in increased expression of STAT3 protein] CTD PMID:35279615 Morroniside multiple interactions ISO Stat3 (Mus musculus) 6480464 morroniside inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:35279615 morusin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 morusin results in decreased phosphorylation of STAT3 protein CTD PMID:25476160 morusin multiple interactions ISO STAT3 (Homo sapiens) 6480464 morusin results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:25476160 myo-inositol hexakisphosphate multiple interactions ISO Stat3 (Mus musculus) 6480464 Phytic Acid inhibits the reaction [Urethane results in increased expression of and results in increased phosphorylation of STAT3 protein] and Phytic Acid inhibits the reaction [Urethane results in increased expression of STAT3 mRNA] CTD PMID:22797328 myricetin multiple interactions ISO Stat3 (Mus musculus) 6480464 myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA] and myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] CTD PMID:18995957 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine decreases expression ISO STAT3 (Homo sapiens) 6480464 N more ... CTD PMID:18778698 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO STAT3 (Homo sapiens) 6480464 TP53 mutant form inhibits the reaction [N more ... CTD PMID:18778698 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO STAT3 (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide multiple interactions EXP 6480464 Tiapride Hydrochloride inhibits the reaction [4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of STAT3 protein] CTD PMID:31231976 N-acetyl-L-cysteine treatment ISO STAT3 (Homo sapiens) 127284846 N-acetyl-L-cysteine co-treated with Il-6 inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of STAT3 protein in the stomach) RGD N-acetyl-L-cysteine decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine results in decreased phosphorylation of STAT3 protein CTD PMID:29894800 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein] and Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]] CTD PMID:21912612 N-acetyl-L-cysteine multiple interactions ISO Stat3 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:16481037 more ... N-acetyl-L-cysteine multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:16896058 more ... N-butyl-N-(4-hydroxybutyl)nitrosamine multiple interactions EXP 6480464 [Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form more ... CTD PMID:29501575 N-butyl-N-(4-hydroxybutyl)nitrosamine increases expression EXP 6480464 Butylhydroxybutylnitrosamine results in increased expression of STAT3 mRNA CTD PMID:35771629 N-ethyl-N-nitrosourea increases mutagenesis ISO Stat3 (Mus musculus) 6480464 Ethylnitrosourea results in increased mutagenesis of STAT3 mRNA CTD PMID:27776689 N-ethyl-N-nitrosourea decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Ethylnitrosourea results in decreased phosphorylation of STAT3 protein CTD PMID:27725143 N-methyl-4-phenylpyridinium decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein CTD PMID:31381935 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of STAT3 mRNA CTD PMID:28801915 N-methyl-4-phenylpyridinium multiple interactions ISO STAT3 (Homo sapiens) 6480464 1 more ... CTD PMID:28958159 more ... N-methyl-4-phenylpyridinium increases expression ISO STAT3 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of STAT3 mRNA and 1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein CTD PMID:28958159 and PMID:35773961 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein CTD PMID:26648565 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 RTN4 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein] and Sirolimus inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein] CTD PMID:26648565 N-nitrosodiethylamine increases phosphorylation ISO Stat3 (Mus musculus) 127285675 N-nitrosodiethylamine increases phosphorylation of Stat3 protein in liver RGD N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of STAT3 protein CTD PMID:29698782 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein and Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 N-phosphocreatine multiple interactions EXP 6480464 Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein] more ... CTD PMID:34455488 N-phosphocreatine increases response to substance EXP 6480464 STAT3 protein results in increased susceptibility to Phosphocreatine CTD PMID:34455488 N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions ISO STAT3 (Homo sapiens) 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:10616907 naringin affects expression ISO Stat3 (Mus musculus) 6480464 naringin affects the expression of STAT3 mRNA and naringin affects the expression of STAT3 protein CTD PMID:25117567 nickel atom increases expression ISO STAT3 (Homo sapiens) 6480464 Nickel results in increased expression of STAT3 mRNA CTD PMID:24768652 and PMID:25583101 nickel atom multiple interactions ISO STAT3 (Homo sapiens) 6480464 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [[Nickel co-treated with lipopolysaccharide more ... CTD PMID:35623502 niclosamide decreases expression ISO STAT3 (Homo sapiens) 6480464 Niclosamide analog results in decreased expression of STAT3 protein and Niclosamide results in decreased expression of STAT3 protein CTD PMID:26116531 and PMID:28284560 niclosamide multiple interactions ISO Stat3 (Mus musculus) 6480464 Niclosamide affects the reaction [FAS protein mutant form affects the phosphorylation of STAT3 protein] CTD PMID:33632240 niclosamide decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Niclosamide analog results in decreased phosphorylation of STAT3 protein and Niclosamide results in decreased phosphorylation of STAT3 protein CTD PMID:23333246 more ... niclosamide multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]] which results in increased susceptibility to Erlotinib Hydrochloride more ... CTD PMID:23894143 more ... nicotine multiple interactions ISO STAT3 (Homo sapiens) 6480464 [alpha-cyano-(3 more ... CTD PMID:18448488 more ... nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:34153408 nicotine affects expression EXP 6480464 Nicotine affects the expression of STAT3 mRNA CTD PMID:29155039 nicotine multiple interactions EXP 6480464 [Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form more ... CTD PMID:29501575 and PMID:34153408 nicotine increases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 results in increased susceptibility to Nicotine CTD PMID:20943775 nicotine increases activity ISO STAT3 (Homo sapiens) 6480464 Nicotine results in increased activity of STAT3 protein CTD PMID:18448488 nicotine increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:18448488 and PMID:35131329 nicotine multiple interactions ISO Stat3 (Mus musculus) 6480464 HMOX1 protein promotes the reaction [Nicotine results in increased phosphorylation of STAT3 protein] more ... CTD PMID:24095726 and PMID:36868510 nicotine increases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein results in increased susceptibility to Nicotine CTD PMID:24095726 nicotine increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Nicotine results in increased phosphorylation of STAT3 protein CTD PMID:24095726 and PMID:25396421 nifuroxazide multiple interactions EXP 6480464 nifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein] CTD PMID:29291386 nimesulide decreases phosphorylation ISO STAT3 (Homo sapiens) 127285656 Nimesulide decreases phoshphorylation of STAT3 in esophagus squamous epithelium RGD nitrofen increases expression EXP 6480464 nitrofen results in increased expression of STAT3 protein modified form CTD PMID:25812446 nitrofurantoin multiple interactions ISO STAT3 (Homo sapiens) 6480464 Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein] and Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]] CTD PMID:15748169 nitrofurantoin increases activity EXP 6480464 Nitrofurantoin results in increased activity of STAT3 protein CTD PMID:11841787 nitrofurantoin increases expression EXP 6480464 Nitrofurantoin results in increased expression of STAT3 mRNA CTD PMID:11841787 nitroglycerin increases expression EXP 6480464 Nitroglycerin results in increased expression of STAT3 mRNA CTD PMID:12102619 Nonylphenol multiple interactions ISO Stat3 (Mus musculus) 6480464 nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of STAT3 protein] CTD PMID:36029577 NORCANTHARIDIN decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 norcantharidin results in decreased phosphorylation of STAT3 protein CTD PMID:21266192 ochratoxin A multiple interactions ISO Stat3 (Mus musculus) 6480464 [ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT3 mRNA CTD PMID:28935500 olanzapine multiple interactions EXP 6480464 olanzapine promotes the reaction [[STAT3 protein binds to RGS7 promoter] which results in increased expression of RGS7 mRNA] and olanzapine promotes the reaction [STAT3 protein binds to RGS7 promoter] CTD PMID:18976543 oleanolic acid increases expression ISO Stat3 (Mus musculus) 6480464 Oleanolic Acid results in increased expression of STAT3 mRNA CTD PMID:18706400 oleanolic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 Oleanolic Acid inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:31306688 oleanolic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of STAT3 mRNA CTD PMID:31401087 oridonin multiple interactions ISO Stat3 (Mus musculus) 6480464 oridonin analog inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:31594861 oridonin multiple interactions ISO STAT3 (Homo sapiens) 6480464 oridonin analog binds to and results in decreased stability of STAT3 protein more ... CTD PMID:31594861 oridonin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 oridonin analog results in decreased phosphorylation of STAT3 protein CTD PMID:31594861 osimertinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 osimertinib affects the reaction [EGF protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:30623574 osimertinib decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 osimertinib results in decreased phosphorylation of STAT3 protein CTD PMID:35970427 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of STAT3 mRNA CTD PMID:25729387 ozone increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Ozone results in increased phosphorylation of STAT3 protein CTD PMID:20826374 and PMID:26342085 ozone multiple interactions ISO Stat3 (Mus musculus) 6480464 [Ovalbumin co-treated with Ozone] results in increased expression of and results in increased phosphorylation of STAT3 protein and [SFTPA2 protein co-treated with Ozone] results in increased expression of STAT3 mRNA CTD PMID:29202868 and PMID:34760922 ozone increases expression ISO Stat3 (Mus musculus) 6480464 Ozone results in increased expression of STAT3 mRNA CTD PMID:26342085 p-tert-Amylphenol increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of STAT3 protein CTD PMID:32466334 paclitaxel multiple interactions ISO STAT3 (Homo sapiens) 6480464 Luteolin promotes the reaction [Paclitaxel results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:20106947 and PMID:24525192 paclitaxel decreases response to substance ISO STAT3 (Homo sapiens) 6480464 STAT3 protein results in decreased susceptibility to Paclitaxel CTD PMID:20106947 paclitaxel decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Paclitaxel results in decreased phosphorylation of STAT3 protein CTD PMID:24525192 paclitaxel decreases activity ISO STAT3 (Homo sapiens) 6480464 Paclitaxel results in decreased activity of STAT3 protein CTD PMID:20106947 palmatine affects binding ISO STAT3 (Homo sapiens) 6480464 palmatine binds to STAT3 protein CTD PMID:35997646 panobinostat multiple interactions ISO STAT3 (Homo sapiens) 6480464 Panobinostat inhibits the reaction [STAT3 protein binds to GADD45G promoter] more ... CTD PMID:23681230 panobinostat increases acetylation ISO STAT3 (Homo sapiens) 6480464 Panobinostat results in increased acetylation of STAT3 protein CTD PMID:26775640 paracetamol affects expression ISO Stat3 (Mus musculus) 6480464 Acetaminophen affects the expression of STAT3 mRNA CTD PMID:17562736 paracetamol increases activity ISO Stat3 (Mus musculus) 6480464 Acetaminophen results in increased activity of STAT3 protein CTD PMID:34726736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of STAT3 mRNA CTD PMID:33387578 paracetamol increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Acetaminophen results in increased phosphorylation of STAT3 protein CTD PMID:25265579 and PMID:32045647 paracetamol increases expression ISO STAT3 (Homo sapiens) 6480464 Acetaminophen results in increased expression of STAT3 mRNA CTD PMID:22230336 paracetamol multiple interactions ISO Stat3 (Mus musculus) 6480464 MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of STAT3 mRNA] and saikosaponin D inhibits the reaction [Acetaminophen results in increased phosphorylation of STAT3 protein] CTD PMID:18700144 and PMID:25265579 paracetamol increases expression ISO Stat3 (Mus musculus) 6480464 Acetaminophen results in increased expression of STAT3 mRNA CTD PMID:11752693 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of STAT3 mRNA CTD PMID:17522070 paraoxon decreases phosphorylation EXP 6480464 Paraoxon results in decreased phosphorylation of STAT3 protein CTD PMID:34778934 paraquat increases expression ISO Stat3 (Mus musculus) 6480464 Paraquat results in increased expression of STAT3 mRNA alternative form CTD PMID:17215068 paraquat increases methylation ISO Stat3 (Mus musculus) 6480464 Paraquat results in increased methylation of STAT3 mRNA CTD PMID:34425375 paraquat multiple interactions ISO Stat3 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA more ... CTD PMID:23963992 and PMID:34425375 paroxetine decreases expression ISO STAT3 (Homo sapiens) 6480464 Paroxetine results in decreased expression of STAT3 mRNA and Paroxetine results in decreased expression of STAT3 protein CTD PMID:17499975 paroxetine multiple interactions ISO STAT3 (Homo sapiens) 6480464 LY 215840 promotes the reaction [Paroxetine results in increased expression of STAT3 mRNA] CTD PMID:32020710 paroxetine increases expression ISO STAT3 (Homo sapiens) 6480464 Paroxetine results in increased expression of STAT3 mRNA CTD PMID:32020710 pentachlorophenol multiple interactions ISO STAT3 (Homo sapiens) 6480464 HMGB1 protein promotes the reaction [Pentachlorophenol results in increased expression of STAT3 mRNA] and HSPA1A protein promotes the reaction [Pentachlorophenol results in increased expression of STAT3 mRNA] CTD PMID:35550411 pentachlorophenol increases expression ISO STAT3 (Homo sapiens) 6480464 Pentachlorophenol results in increased expression of STAT3 mRNA and Pentachlorophenol results in increased expression of STAT3 protein CTD PMID:35550411 perfluorooctane-1-sulfonic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of STAT3 mRNA CTD PMID:36331819 phenethyl caffeate multiple interactions ISO Stat3 (Mus musculus) 6480464 caffeic acid phenethyl ester inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein] CTD PMID:22155090 phenethyl caffeate multiple interactions ISO STAT3 (Homo sapiens) 6480464 caffeic acid phenethyl ester analog affects the expression of and affects the phosphorylation of STAT3 protein CTD PMID:32125059 phenformin increases expression EXP 6480464 Phenformin results in increased expression of STAT3 mRNA CTD PMID:31324951 phenobarbital affects expression ISO Stat3 (Mus musculus) 6480464 Phenobarbital affects the expression of STAT3 mRNA CTD PMID:23091169 phenylarsine oxide multiple interactions ISO STAT3 (Homo sapiens) 6480464 Hydrogen Peroxide promotes the reaction [oxophenylarsine affects the localization of STAT3 protein] more ... CTD PMID:10364193 and PMID:11882386 phenylarsine oxide affects localization ISO STAT3 (Homo sapiens) 6480464 oxophenylarsine affects the localization of STAT3 protein CTD PMID:10364193 phenylarsine oxide multiple interactions ISO Stat3 (Mus musculus) 6480464 oxophenylarsine inhibits the reaction [EGF protein affects the localization of and results in increased activity of STAT3 protein] CTD PMID:12093727 phenylephrine affects localization EXP 6480464 Phenylephrine affects the localization of STAT3 protein CTD PMID:19299911 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of STAT3 CTD PMID:19299911 phenylephrine multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] more ... CTD PMID:19299911 and PMID:27094369 phenylpropanolamine increases activity EXP 6480464 Phenylpropanolamine results in increased activity of STAT3 protein CTD PMID:24792324 phenylpropanolamine increases expression EXP 6480464 Phenylpropanolamine results in increased expression of STAT3 mRNA and Phenylpropanolamine results in increased expression of STAT3 protein modified form CTD PMID:24792324 phenylpropanolamine multiple interactions EXP 6480464 Enzyme Inhibitors inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 protein modified form] more ... CTD PMID:24792324 phenylpropanolamine increases response to substance EXP 6480464 STAT3 mRNA results in increased susceptibility to Phenylpropanolamine CTD PMID:24792324 PhIP multiple interactions ISO STAT3 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of STAT3 mRNA] CTD PMID:29362861 PhIP increases expression ISO STAT3 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of STAT3 mRNA CTD PMID:29362861 phorbol 13-acetate 12-myristate increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein CTD PMID:20523355 and PMID:24496235 phorbol 13-acetate 12-myristate affects localization ISO STAT3 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate affects the localization of STAT3 protein CTD PMID:30133131 phorbol 13-acetate 12-myristate increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein CTD PMID:22986104 and PMID:26513295 phorbol 13-acetate 12-myristate increases expression ISO Stat3 (Mus musculus) 6480464 Tetradecanoylphorbol Acetate results in increased expression of STAT3 CTD PMID:26100520 phorbol 13-acetate 12-myristate multiple interactions ISO Stat3 (Mus musculus) 6480464 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]] more ... CTD PMID:22986104 more ... phorbol 13-acetate 12-myristate multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in decreased phosphorylation of STAT3 protein and diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] CTD PMID:20523355 and PMID:25128825 phorone increases activity EXP 6480464 phorone results in increased activity of STAT3 protein CTD PMID:11841787 phorone increases expression EXP 6480464 phorone results in increased expression of STAT3 mRNA CTD PMID:11841787 phosphatidic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 Phosphatidic Acids results in increased phosphorylation of and affects the localization of STAT3 protein CTD PMID:16354768 physostigmine decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Physostigmine results in decreased phosphorylation of STAT3 protein CTD PMID:28500787 piperine multiple interactions ISO Stat3 (Mus musculus) 6480464 piperine inhibits the reaction [IL2 protein results in increased phosphorylation of STAT3 protein] CTD PMID:25655587 pipoxolan multiple interactions ISO Stat3 (Mus musculus) 6480464 pipoxolan inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein] CTD PMID:32677756 pirinixic acid decreases expression ISO Stat3 (Mus musculus) 6480464 pirinixic acid results in decreased expression of STAT3 mRNA CTD PMID:17321000 pirinixic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein] more ... CTD PMID:17321000 and PMID:27853831 pirinixic acid increases expression ISO Stat3 (Mus musculus) 6480464 pirinixic acid results in increased expression of STAT3 mRNA CTD PMID:18445702 piroxicam multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of STAT3 mRNA CTD PMID:21858171 platycodin D multiple interactions ISO Stat3 (Mus musculus) 6480464 platycodin D inhibits the reaction [[IL6 protein co-treated with TGFB1 protein] results in increased phosphorylation of STAT3 protein] CTD PMID:25887267 poly(I:C) multiple interactions ISO Stat3 (Mus musculus) 6480464 IL6 protein affects the reaction [Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein] and Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein CTD PMID:21195166 Ponicidin decreases phosphorylation ISO STAT3 (Homo sapiens) 127285620 Ponicidin decreases phosphorylation of STAT3 protein in the stomach RGD potassium dichromate multiple interactions ISO STAT3 (Homo sapiens) 6480464 LCK protein affects the reaction [Potassium Dichromate results in increased phosphorylation of STAT3 protein alternative form] more ... CTD PMID:17078813 and PMID:37146930 pravastatin decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Pravastatin results in decreased phosphorylation of STAT3 protein CTD PMID:19330073 progesterone multiple interactions ISO STAT3 (Homo sapiens) 6480464 Progesterone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:21768398 propiconazole decreases expression ISO Stat3 (Mus musculus) 6480464 propiconazole results in decreased expression of STAT3 mRNA CTD PMID:21278054 propionic acid increases expression EXP 6480464 propionic acid results in increased expression of STAT3 protein CTD PMID:32481507 propofol decreases phosphorylation ISO STAT3 (Homo sapiens) 125097524 Propofol decreases phosphorylation of STAT3 protein in colon epithelium RGD propofol multiple interactions EXP 6480464 HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]] more ... CTD PMID:24810525 propofol increases phosphorylation EXP 6480464 Propofol results in increased phosphorylation of STAT3 protein CTD PMID:24810525 propranolol multiple interactions ISO STAT3 (Homo sapiens) 6480464 Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 and PMID:20106947 prostaglandin E2 multiple interactions ISO Stat3 (Mus musculus) 6480464 Dinoprostone inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein] and Dinoprostone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]] CTD PMID:21268125 and PMID:25432964 pterostilbene decreases expression ISO STAT3 (Homo sapiens) 6480464 pterostilbene results in decreased expression of STAT3 protein modified form CTD PMID:22450950 pterostilbene decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 pterostilbene results in decreased phosphorylation of STAT3 protein CTD PMID:26138072 pterostilbene decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 pterostilbene results in decreased phosphorylation of STAT3 protein CTD PMID:26138072 pterostilbene decreases activity ISO STAT3 (Homo sapiens) 6480464 pterostilbene results in decreased activity of STAT3 protein CTD PMID:23313376 Punicalagin affects localization ISO STAT3 (Homo sapiens) 6480464 punicalagin affects the localization of STAT3 protein CTD PMID:33720461 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased expression of STAT3 mRNA] CTD PMID:11578593 quartz multiple interactions ISO Stat3 (Mus musculus) 6480464 Nicotine inhibits the reaction [Quartz results in decreased phosphorylation of STAT3 protein] and staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased phosphorylation of STAT3 protein] CTD PMID:36868510 quartz decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Quartz results in decreased phosphorylation of STAT3 protein CTD PMID:36868510 quercetin decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 Quercetin results in decreased phosphorylation of STAT3 protein CTD PMID:24275163 quercetin increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Quercetin results in increased phosphorylation of STAT3 protein CTD PMID:22230496 quercetin multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Docetaxel co-treated with epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein more ... CTD PMID:20153296 more ... quercetin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of STAT3 protein CTD PMID:24275163 and PMID:27468969 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [cypermethrin results in increased expression of STAT3 mRNA] more ... CTD PMID:22426011 more ... quercetin decreases expression ISO Stat3 (Mus musculus) 6480464 Quercetin results in decreased expression of STAT3 mRNA CTD PMID:24275163 quercetin 3-O-beta-D-glucofuranoside increases expression ISO STAT3 (Homo sapiens) 6480464 isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 quercetin 3-O-beta-D-glucopyranoside increases expression ISO STAT3 (Homo sapiens) 6480464 isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 raloxifene multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:17336289 more ... raloxifene multiple interactions ISO Stat3 (Mus musculus) 6480464 Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the phosphorylation of STAT3 protein] more ... CTD PMID:32828944 raloxifene decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased phosphorylation of STAT3 protein CTD PMID:24456369 more ... raloxifene multiple interactions EXP 6480464 Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:32828944 reactive oxygen species multiple interactions ISO Stat3 (Mus musculus) 6480464 [[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein] more ... CTD PMID:23376140 reparixin multiple interactions ISO STAT3 (Homo sapiens) 6480464 reparixin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of STAT3 protein] CTD PMID:33396024 resiquimod increases expression ISO Stat3 (Mus musculus) 6480464 resiquimod results in increased expression of STAT3 mRNA CTD PMID:17238832 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA] and Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 protein] CTD PMID:23421680 resveratrol increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 resveratrol results in increased phosphorylation of STAT3 protein CTD PMID:22748497 resveratrol decreases expression ISO STAT3 (Homo sapiens) 6480464 resveratrol results in decreased expression of STAT3 more ... CTD PMID:18592012 more ... resveratrol decreases activity ISO STAT3 (Homo sapiens) 6480464 resveratrol results in decreased activity of STAT3 protein CTD PMID:21503893 and PMID:25061499 resveratrol affects activity ISO STAT3 (Homo sapiens) 6480464 resveratrol affects the activity of STAT3 protein CTD PMID:25063218 resveratrol affects localization ISO STAT3 (Homo sapiens) 6480464 resveratrol affects the localization of STAT3 protein CTD PMID:18592012 more ... resveratrol decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of STAT3 protein CTD PMID:18592012 more ... resveratrol increases expression ISO Stat3 (Mus musculus) 6480464 resveratrol results in increased expression of STAT3 protein CTD PMID:25505154 resveratrol decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 resveratrol results in decreased phosphorylation of STAT3 protein CTD PMID:26138072 resveratrol increases phosphorylation ISO Stat3 (Mus musculus) 6480464 resveratrol results in increased phosphorylation of STAT3 protein CTD PMID:21342247 resveratrol increases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein results in increased susceptibility to resveratrol CTD PMID:21342247 resveratrol decreases acetylation ISO STAT3 (Homo sapiens) 6480464 resveratrol results in decreased acetylation of STAT3 protein CTD PMID:23681230 resveratrol decreases expression ISO Stat3 (Mus musculus) 6480464 resveratrol results in decreased expression of STAT3 protein modified form CTD PMID:19063842 resveratrol multiple interactions ISO Stat3 (Mus musculus) 6480464 IL10 protein affects the reaction [Resveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]] more ... CTD PMID:19796711 more ... resveratrol multiple interactions ISO STAT3 (Homo sapiens) 6480464 6-chloro-2 more ... CTD PMID:16546976 more ... Rhynchophylline multiple interactions EXP 6480464 rhyncophylline inhibits the reaction [4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of STAT3 protein] CTD PMID:31231976 rimonabant multiple interactions ISO Stat3 (Mus musculus) 6480464 Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein] CTD PMID:16046413 risperidone multiple interactions EXP 6480464 Risperidone inhibits the reaction [Rotenone results in decreased expression of STAT3 mRNA] CTD PMID:17442543 ritodrine increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Ritodrine results in increased phosphorylation of STAT3 protein CTD PMID:23370008 ritonavir decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Ritonavir results in decreased phosphorylation of STAT3 protein CTD PMID:21270666 rofecoxib increases expression ISO STAT3 (Homo sapiens) 6480464 rofecoxib results in increased expression of STAT3 mRNA CTD PMID:17070997 rotenone multiple interactions ISO STAT3 (Homo sapiens) 6480464 Rotenone inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:15748169 and PMID:19635391 rotenone decreases expression ISO STAT3 (Homo sapiens) 6480464 Rotenone results in decreased expression of STAT3 mRNA and Rotenone results in decreased expression of STAT3 protein CTD PMID:31408661 rotenone increases expression EXP 6480464 Rotenone results in increased expression of STAT3 mRNA CTD PMID:28374803 rotenone affects response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein affects the susceptibility to Rotenone CTD PMID:20224768 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of STAT3 mRNA CTD PMID:17442543 rotenone multiple interactions EXP 6480464 Risperidone inhibits the reaction [Rotenone results in decreased expression of STAT3 mRNA] CTD PMID:17442543 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA] and Rutin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein] CTD PMID:22426011 and PMID:26062544 ruxolitinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of STAT3 protein and ruxolitinib inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein] CTD PMID:24820114 and PMID:30012499 S-butyl-DL-homocysteine (S,R)-sulfoximine increases activity EXP 6480464 Buthionine Sulfoximine results in increased activity of STAT3 protein CTD PMID:11841787 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO Stat3 (Mus musculus) 6480464 [Troglitazone co-treated with Buthionine Sulfoximine] results in increased phosphorylation of STAT3 protein CTD PMID:31294483 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression EXP 6480464 Buthionine Sulfoximine results in increased expression of STAT3 mRNA CTD PMID:11841787 Salinomycin multiple interactions ISO STAT3 (Homo sapiens) 6480464 salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:32822738 sarpogrelate multiple interactions ISO STAT3 (Homo sapiens) 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] and sarpogrelate inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 sarpogrelate multiple interactions ISO Stat3 (Mus musculus) 6480464 [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] and sarpogrelate inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 SB 203580 multiple interactions ISO STAT3 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [1 more ... CTD PMID:30871965 and PMID:33030807 SB 203580 increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 SB 203580 results in increased phosphorylation of STAT3 protein CTD PMID:33030807 SB 431542 multiple interactions ISO STAT3 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of STAT3 protein CTD PMID:37664457 Se-methyl-L-selenocysteine multiple interactions ISO STAT3 (Homo sapiens) 6480464 selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter] and STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 Se-methylselenocysteine multiple interactions ISO STAT3 (Homo sapiens) 6480464 selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter] and STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 selenic acid increases activity ISO STAT3 (Homo sapiens) 6480464 Selenic Acid results in increased activity of STAT3 protein CTD PMID:22366233 sertraline decreases expression ISO STAT3 (Homo sapiens) 6480464 Sertraline results in decreased expression of STAT3 mRNA and Sertraline results in decreased expression of STAT3 protein CTD PMID:17499975 silicon dioxide multiple interactions ISO Stat3 (Mus musculus) 6480464 [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA more ... CTD PMID:20490462 more ... silicon dioxide increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Silicon Dioxide results in increased phosphorylation of STAT3 protein CTD PMID:30658076 silicon dioxide multiple interactions ISO STAT3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Silicon Dioxide results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:29894800 silicon dioxide increases expression ISO Stat3 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of STAT3 mRNA CTD PMID:20490462 and PMID:23221170 simvastatin decreases activity ISO STAT3 (Homo sapiens) 6480464 Simvastatin results in decreased activity of STAT3 protein CTD PMID:19886038 simvastatin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Simvastatin results in decreased phosphorylation of STAT3 protein CTD PMID:18453621 and PMID:21910007 simvastatin decreases phosphorylation EXP 6480464 Simvastatin results in decreased phosphorylation of STAT3 protein CTD PMID:18400235 simvastatin decreases activity ISO Stat3 (Mus musculus) 6480464 Simvastatin results in decreased activity of STAT3 protein CTD PMID:19886038 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]] more ... CTD PMID:16534557 more ... simvastatin affects expression ISO Stat3 (Mus musculus) 6480464 Simvastatin affects the expression of STAT3 protein CTD PMID:17507688 simvastatin multiple interactions ISO STAT3 (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT3 protein] CTD PMID:18453621 sirolimus decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Sirolimus results in decreased phosphorylation of STAT3 protein CTD PMID:20038814 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein] CTD PMID:26648565 sirolimus decreases phosphorylation EXP 6480464 Sirolimus results in decreased phosphorylation of STAT3 protein CTD PMID:16391472 sirolimus multiple interactions ISO STAT3 (Homo sapiens) 6480464 Sirolimus inhibits the reaction [IFNG protein results in decreased phosphorylation of STAT3 protein] CTD PMID:16427044 sodium arsenate decreases expression ISO Stat3 (Mus musculus) 6480464 sodium arsenate results in decreased expression of STAT3 mRNA CTD PMID:30953684 sodium arsenite multiple interactions ISO STAT3 (Homo sapiens) 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA more ... CTD PMID:15116095 more ... sodium arsenite increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of STAT3 protein CTD PMID:26101800 more ... sodium arsenite decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 sodium arsenite results in decreased phosphorylation of STAT3 protein CTD PMID:29039521 sodium arsenite increases expression ISO STAT3 (Homo sapiens) 6480464 sodium arsenite results in increased expression of STAT3 mRNA CTD PMID:28444938 sodium arsenite decreases expression ISO Stat3 (Mus musculus) 6480464 sodium arsenite results in decreased expression of STAT3 mRNA and sodium arsenite results in decreased expression of STAT3 protein modified form CTD PMID:23143138 and PMID:28370166 sodium arsenite increases phosphorylation ISO Stat3 (Mus musculus) 6480464 sodium arsenite results in increased phosphorylation of STAT3 protein CTD PMID:20008137 and PMID:26631322 sodium arsenite decreases response to substance ISO Stat3 (Mus musculus) 6480464 STAT3 protein results in decreased susceptibility to sodium arsenite CTD PMID:23143138 sodium arsenite multiple interactions ISO Stat3 (Mus musculus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein] more ... CTD PMID:20008137 more ... sodium arsenite decreases expression ISO STAT3 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of STAT3 CTD PMID:17224793 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of STAT3 mRNA CTD PMID:25993096 solasodine decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 solasodine results in decreased phosphorylation of STAT3 protein CTD PMID:37121296 Soman increases expression EXP 6480464 Soman results in increased expression of STAT3 mRNA CTD PMID:19281266 sorafenib decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 sorafenib analog results in decreased phosphorylation of STAT3 protein and sorafenib results in decreased phosphorylation of STAT3 protein CTD PMID:19001435 more ... sorafenib multiple interactions ISO STAT3 (Homo sapiens) 6480464 resveratrol promotes the reaction [sorafenib results in decreased phosphorylation of STAT3 protein] more ... CTD PMID:18512153 more ... sorafenib affects localization ISO Stat3 (Mus musculus) 6480464 sorafenib affects the localization of STAT3 protein CTD PMID:21360571 sphingosine 1-phosphate multiple interactions ISO STAT3 (Homo sapiens) 6480464 Janus Kinase Inhibitors inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of STAT3 protein] more ... CTD PMID:32401414 sphingosine 1-phosphate increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 sphingosine 1-phosphate results in increased phosphorylation of STAT3 protein CTD PMID:32401414 stattic multiple interactions ISO STAT3 (Homo sapiens) 127284846 Stattic inhibits the reaction [Il-6 increases phosphorylation of STAT3 protein in the stomach) RGD stattic multiple interactions EXP 6480464 stattic inhibits the reaction [zoniporide results in increased phosphorylation of STAT3 protein] CTD PMID:20942815 stattic multiple interactions ISO Stat3 (Mus musculus) 6480464 stattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] more ... CTD PMID:22454431 more ... stattic decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 stattic results in decreased phosphorylation of STAT3 protein CTD PMID:24627483 stattic multiple interactions ISO STAT3 (Homo sapiens) 6480464 stattic affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein] more ... CTD PMID:23255093 more ... staurosporine multiple interactions ISO STAT3 (Homo sapiens) 6480464 Staurosporine inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 stavudine decreases expression EXP 6480464 Stavudine results in decreased expression of STAT3 mRNA CTD PMID:18299183 stilbenoid affects activity ISO STAT3 (Homo sapiens) 6480464 Stilbenes analog affects the activity of STAT3 protein CTD PMID:25063218 streptozocin multiple interactions EXP 6480464 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA] more ... CTD PMID:19958114 more ... streptozocin decreases phosphorylation EXP 6480464 Streptozocin results in decreased phosphorylation of STAT3 protein CTD PMID:21912612 and PMID:24810525 streptozocin increases phosphorylation EXP 6480464 Streptozocin results in increased phosphorylation of STAT3 protein CTD PMID:20821229 more ... streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of STAT3 mRNA and Streptozocin results in increased expression of STAT3 protein CTD PMID:19958114 and PMID:36650709 SU6656 multiple interactions ISO Stat3 (Mus musculus) 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:23376140 succinic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 [Oleanolic Acid analog binds to Succinic Acid] which results in decreased expression of STAT3 mRNA CTD PMID:31401087 sulfasalazine multiple interactions ISO Stat3 (Mus musculus) 6480464 Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein] CTD PMID:32272095 sulforaphane decreases expression ISO STAT3 (Homo sapiens) 6480464 sulforaphane results in decreased expression of STAT3 mRNA CTD PMID:31838189 sulindac multiple interactions ISO STAT3 (Homo sapiens) 6480464 BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein modified form] and BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein] CTD PMID:17401459 sulindac decreases expression ISO STAT3 (Homo sapiens) 6480464 Sulindac results in decreased expression of STAT3 protein and Sulindac results in decreased expression of STAT3 protein modified form CTD PMID:17401459 sulindac decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Sulindac results in decreased phosphorylation of STAT3 protein CTD PMID:11861373 sulindac sulfide multiple interactions ISO STAT3 (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of and results in decreased phosphorylation of STAT3 protein CTD PMID:17566705 sulindac sulfide decreases expression ISO STAT3 (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of STAT3 mRNA CTD PMID:17566705 sunitinib decreases expression ISO STAT3 (Homo sapiens) 6480464 Sunitinib results in decreased expression of STAT3 mRNA CTD PMID:31533062 syringic acid decreases expression ISO STAT3 (Homo sapiens) 6480464 syringic acid results in decreased expression of STAT3 mRNA CTD PMID:33759321 T-2 toxin multiple interactions ISO Stat3 (Mus musculus) 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 T-2 toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of STAT3 mRNA CTD PMID:26141394 T-2 toxin increases expression ISO Stat3 (Mus musculus) 6480464 T-2 Toxin results in increased expression of STAT3 mRNA CTD PMID:22454431 T-2 toxin increases phosphorylation ISO Stat3 (Mus musculus) 6480464 T-2 Toxin results in increased phosphorylation of STAT3 protein CTD PMID:22454431 tacrolimus hydrate increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Tacrolimus results in increased phosphorylation of STAT3 protein CTD PMID:23958496 tamoxifen multiple interactions ISO STAT3 (Homo sapiens) 6480464 Tamoxifen inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]] more ... CTD PMID:14975756 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of STAT3 protein modified form CTD PMID:17901229 tamoxifen multiple interactions ISO Stat3 (Mus musculus) 6480464 Tamoxifen inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:16860915 Tanshinone I multiple interactions ISO STAT3 (Homo sapiens) 6480464 tanshinone inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein] CTD PMID:35304817 taurine decreases expression ISO STAT3 (Homo sapiens) 6480464 Taurine results in decreased expression of STAT3 mRNA CTD PMID:16579726 taurocholic acid multiple interactions ISO STAT3 (Homo sapiens) 6480464 sorafenib inhibits the reaction [Taurocholic Acid results in increased phosphorylation of STAT3 protein] CTD PMID:18512153 taurocholic acid increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Taurocholic Acid results in increased phosphorylation of STAT3 protein CTD PMID:18512153 tert-butyl hydroperoxide multiple interactions ISO STAT3 (Homo sapiens) 6480464 3 and 4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of STAT3 protein] CTD PMID:29128606 tert-butyl hydroperoxide decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased phosphorylation of STAT3 protein CTD PMID:29128606 testosterone multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of STAT3 protein modified form] CTD PMID:32628957 testosterone increases expression ISO Stat3 (Mus musculus) 6480464 Testosterone deficiency results in increased expression of STAT3 mRNA CTD PMID:33848595 testosterone increases expression EXP 6480464 Testosterone results in increased expression of STAT3 protein modified form CTD PMID:32628957 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of STAT3 mRNA CTD PMID:17522070 and PMID:26062544 tetrachloromethane increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Carbon Tetrachloride results in increased phosphorylation of STAT3 protein CTD PMID:14999682 more ... tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of STAT3 protein CTD PMID:17009398 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of STAT3 mRNA CTD PMID:16239168 tetrachloromethane multiple interactions ISO Stat3 (Mus musculus) 6480464 2 more ... CTD PMID:12730884 more ... tetrachloromethane increases activity ISO Stat3 (Mus musculus) 6480464 Carbon Tetrachloride results in increased activity of STAT3 protein CTD PMID:12730884 and PMID:12830005 tetrachloromethane multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA] CTD PMID:26062544 tetracycline increases expression EXP 6480464 Tetracycline results in increased expression of STAT3 mRNA CTD PMID:17522070 thalidomide decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Thalidomide analog results in decreased phosphorylation of STAT3 protein CTD PMID:15858615 thalidomide multiple interactions ISO STAT3 (Homo sapiens) 6480464 [resveratrol co-treated with Thalidomide] results in decreased phosphorylation of STAT3 protein and Thalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein] CTD PMID:17164350 and PMID:17505005 thapsigargin multiple interactions EXP 6480464 Thapsigargin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] CTD PMID:19285962 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of STAT3 protein CTD PMID:35544339 thapsigargin increases expression ISO Stat3 (Mus musculus) 6480464 Thapsigargin results in increased expression of STAT3 protein CTD PMID:24648495 theobromine multiple interactions EXP 127229954 [Theobromine co-treated with Theanine] inhibits the reaction [1 more ... RGD theophylline increases expression ISO STAT3 (Homo sapiens) 6480464 Theophylline results in increased expression of STAT3 mRNA CTD PMID:16083514 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of STAT3 mRNA CTD PMID:34492290 thymoquinone multiple interactions ISO STAT3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of and results in decreased activity of STAT3 protein] more ... CTD PMID:31433961 and PMID:34627931 thymoquinone multiple interactions ISO Stat3 (Mus musculus) 6480464 Doxorubicin promotes the reaction [thymoquinone results in decreased phosphorylation of STAT3 protein] and thymoquinone inhibits the reaction [Doxorubicin results in increased phosphorylation of STAT3 protein] CTD PMID:34605108 thymoquinone decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 thymoquinone results in decreased phosphorylation of STAT3 protein CTD PMID:34627931 thymoquinone decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 thymoquinone results in decreased phosphorylation of STAT3 protein CTD PMID:34605108 thyroxine increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Thyroxine results in increased phosphorylation of STAT3 protein CTD PMID:31336132 thyroxine multiple interactions ISO STAT3 (Homo sapiens) 6480464 NSC 74859 inhibits the reaction [Thyroxine results in increased phosphorylation of STAT3 protein] CTD PMID:31336132 tofacitinib decreases activity ISO STAT3 (Homo sapiens) 6480464 tofacitinib results in decreased activity of STAT3 protein CTD PMID:22348037 tofacitinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 tofacitinib inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21383241 more ... tofacitinib multiple interactions ISO Stat3 (Mus musculus) 6480464 tofacitinib inhibits the reaction [IL1B protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:21383241 more ... tofacitinib decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 tofacitinib results in decreased phosphorylation of STAT3 protein CTD PMID:25487280 and PMID:26244872 tofacitinib decreases expression ISO STAT3 (Homo sapiens) 6480464 tofacitinib results in decreased expression of STAT3 protein modified form CTD PMID:25398374 and PMID:27059729 tolcapone increases expression EXP 6480464 tolcapone results in increased expression of STAT3 mRNA CTD PMID:24136188 toluene increases expression ISO Stat3 (Mus musculus) 6480464 Toluene results in increased expression of STAT3 mRNA CTD PMID:21601613 toosendanin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 toosendanin results in decreased phosphorylation of STAT3 protein CTD PMID:37946196 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of STAT3 mRNA CTD PMID:25729387 torcetrapib increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 torcetrapib results in increased phosphorylation of STAT3 protein CTD PMID:25617244 Trachelogenin multiple interactions ISO STAT3 (Homo sapiens) 6480464 trachelogenin inhibits the reaction [IL6 results in increased expression of STAT3 protein] CTD PMID:25100250 trametinib multiple interactions ISO STAT3 (Homo sapiens) 6480464 physapubescin B inhibits the reaction [trametinib results in increased phosphorylation of STAT3 protein] CTD PMID:33035574 trametinib increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 trametinib results in increased phosphorylation of STAT3 protein CTD PMID:33035574 triadimefon decreases expression EXP 6480464 triadimefon results in decreased expression of STAT3 protein CTD PMID:36179991 trichloroethene multiple interactions ISO STAT3 (Homo sapiens) 6480464 Curcumin inhibits the reaction [Trichloroethylene results in increased phosphorylation of STAT3 protein] CTD PMID:34233590 trichloroethene increases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Trichloroethylene results in increased phosphorylation of STAT3 protein CTD PMID:34233590 trimethyltin increases expression ISO Stat3 (Mus musculus) 6480464 trimethyltin results in increased expression of STAT3 mRNA and trimethyltin results in increased expression of STAT3 protein CTD PMID:21435392 Triptolide increases expression ISO Stat3 (Mus musculus) 6480464 triptolide results in increased expression of STAT3 mRNA CTD PMID:24949944 Triptolide multiple interactions ISO STAT3 (Homo sapiens) 6480464 triptolide results in decreased expression of and results in decreased phosphorylation of STAT3 protein CTD PMID:38115356 troglitazone increases expression ISO Stat3 (Mus musculus) 6480464 Troglitazone results in increased expression of STAT3 mRNA CTD PMID:31294483 troglitazone multiple interactions ISO Stat3 (Mus musculus) 6480464 [Troglitazone co-treated with Buthionine Sulfoximine] results in increased phosphorylation of STAT3 protein CTD PMID:31294483 troglitazone increases phosphorylation ISO Stat3 (Mus musculus) 6480464 Troglitazone results in increased phosphorylation of STAT3 protein CTD PMID:31294483 trovafloxacin multiple interactions ISO Stat3 (Mus musculus) 6480464 [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of STAT3 mRNA CTD PMID:18930950 tubastatin A decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 tubastatin A results in decreased phosphorylation of STAT3 protein CTD PMID:26775640 tubastatin A decreases phosphorylation ISO Stat3 (Mus musculus) 6480464 tubastatin A results in decreased phosphorylation of STAT3 protein CTD PMID:26775640 tungsten decreases expression ISO Stat3 (Mus musculus) 6480464 Tungsten results in decreased expression of STAT3 mRNA CTD PMID:30912803 tyrphostin AG 1478 multiple interactions ISO STAT3 (Homo sapiens) 6480464 RTKI cpd inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA] and RTKI cpd inhibits the reaction [EGF protein results in increased activity of STAT3 protein] CTD PMID:21909620 and PMID:25841994 tyrphostin AG 1478 decreases expression ISO STAT3 (Homo sapiens) 6480464 RTKI cpd results in decreased expression of STAT3 protein modified form CTD PMID:29974605 tyrphostin AG 1478 multiple interactions ISO Stat3 (Mus musculus) 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] and [RTKI cpd results in decreased activity of EGFR protein] which results in decreased phosphorylation of STAT3 protein CTD PMID:21268125 and PMID:23376140 tyrphostin B42 multiple interactions ISO STAT3 (Homo sapiens) 127284886 tyrphostin B42 co-treated with N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases phosphorylation of STAT3 protein in stomach] RGD U50488 multiple interactions ISO Stat3 (Mus musculus) 6480464 [3 more ... CTD PMID:18385270 umbelliferone multiple interactions EXP 6480464 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA] and 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 protein] CTD PMID:36650709 urethane decreases expression ISO Stat3 (Mus musculus) 6480464 Urethane results in decreased expression of STAT3 mRNA CTD PMID:12400877 urethane increases expression ISO STAT3 (Homo sapiens) 6480464 Urethane results in increased expression of STAT3 mRNA CTD PMID:28818685 urethane increases expression ISO Stat3 (Mus musculus) 6480464 Urethane results in increased expression of STAT3 mRNA CTD PMID:22797328 urethane multiple interactions ISO Stat3 (Mus musculus) 6480464 Phytic Acid inhibits the reaction [Urethane results in increased expression of and results in increased phosphorylation of STAT3 protein] more ... CTD PMID:22797328 ursodeoxycholic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 Ursodeoxycholic Acid inhibits the reaction [3 more ... CTD PMID:38104874 ursolic acid multiple interactions ISO Stat3 (Mus musculus) 6480464 Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]] more ... CTD PMID:26100520 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of STAT3 mRNA CTD PMID:24136188 valproic acid increases expression ISO Stat3 (Mus musculus) 6480464 Valproic Acid results in increased expression of STAT3 mRNA CTD PMID:21427059 valproic acid increases expression ISO STAT3 (Homo sapiens) 6480464 Valproic Acid results in increased expression of STAT3 mRNA CTD PMID:19101580 more ... valproic acid affects expression ISO STAT3 (Homo sapiens) 6480464 Valproic Acid affects the expression of STAT3 mRNA CTD PMID:25979313 valsartan multiple interactions ISO STAT3 (Homo sapiens) 6480464 Valsartan inhibits the reaction [AGT protein affects the localization of STAT3 protein] more ... CTD PMID:12846741 vanadium atom multiple interactions EXP 6480464 Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein] CTD PMID:16195403 vanadium(0) multiple interactions EXP 6480464 Vanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein] CTD PMID:16195403 vanadyl sulfate increases expression ISO STAT3 (Homo sapiens) 6480464 vanadyl sulfate results in increased expression of STAT3 mRNA CTD PMID:16330358 vancomycin decreases expression ISO Stat3 (Mus musculus) 6480464 Vancomycin results in decreased expression of STAT3 mRNA CTD PMID:18930951 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein] and Verapamil inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] CTD PMID:19299911 verteporfin multiple interactions ISO Stat3 (Mus musculus) 6480464 Verteporfin inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased expression of and results in increased phosphorylation of STAT3 protein] CTD PMID:31812773 verteporfin decreases expression ISO Stat3 (Mus musculus) 6480464 Verteporfin results in decreased expression of STAT3 protein CTD PMID:31812773 vincaleukoblastine multiple interactions ISO STAT3 (Homo sapiens) 6480464 Vinblastine deficiency results in decreased activity of and affects the localization of STAT3 protein CTD PMID:28086195 vincristine increases expression EXP 6480464 Vincristine results in increased expression of STAT3 protein CTD PMID:36808657 vincristine multiple interactions EXP 6480464 Quercetin inhibits the reaction [Vincristine results in increased expression of STAT3 protein] CTD PMID:36808657 withaferin A multiple interactions ISO Stat3 (Mus musculus) 6480464 withaferin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:21396905 wogonin decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 wogonin results in decreased phosphorylation of STAT3 protein CTD PMID:32671444 zinc atom decreases activity EXP 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc atom decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Zinc deficiency results in decreased phosphorylation of STAT3 protein CTD PMID:28086195 zinc atom multiple interactions EXP 6480464 Zinc deficiency results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:28086195 zinc atom increases expression ISO Stat3 (Mus musculus) 6480464 Zinc deficiency results in increased expression of STAT3 mRNA and Zinc results in increased expression of STAT3 mRNA CTD PMID:31505237 zinc atom multiple interactions ISO STAT3 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [Zinc deficiency affects the localization of STAT3 protein] CTD PMID:28086195 zinc atom decreases activity ISO STAT3 (Homo sapiens) 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc protoporphyrin multiple interactions ISO Stat3 (Mus musculus) 6480464 zinc protoporphyrin inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:24095726 zinc protoporphyrin multiple interactions EXP 6480464 zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]] and zinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]] CTD PMID:24810525 zinc sulfate multiple interactions ISO STAT3 (Homo sapiens) 6480464 Zinc Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] CTD PMID:16896058 zinc(0) multiple interactions ISO STAT3 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [Zinc deficiency affects the localization of STAT3 protein] CTD PMID:28086195 zinc(0) increases expression ISO Stat3 (Mus musculus) 6480464 Zinc deficiency results in increased expression of STAT3 mRNA and Zinc results in increased expression of STAT3 mRNA CTD PMID:31505237 zinc(0) decreases activity EXP 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc(0) decreases activity ISO STAT3 (Homo sapiens) 6480464 Zinc deficiency results in decreased activity of STAT3 protein CTD PMID:28086195 zinc(0) decreases phosphorylation ISO STAT3 (Homo sapiens) 6480464 Zinc deficiency results in decreased phosphorylation of STAT3 protein CTD PMID:28086195 zinc(0) multiple interactions EXP 6480464 Zinc deficiency results in decreased phosphorylation of and affects the localization of STAT3 protein CTD PMID:28086195 zoledronic acid increases expression ISO STAT3 (Homo sapiens) 6480464 zoledronic acid results in increased expression of STAT3 mRNA CTD PMID:24714768
