CHEBI:16704 - uridine

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ChEBI Name uridine ChEBI ID CHEBI:16704 Definition A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a β‒N1-glycosidic bond. Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:46391, CHEBI:46460, CHEBI:46463, CHEBI:46386, CHEBI:9893, CHEBI:15296, CHEBI:27227 Supplier Information eMolecules:636962, ZINC000100044649 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Pitavastatin (usually as a calcium salt) is a member of the blood cholesterol lowering medication class of statins. Pitavastatin is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis. It was patented in 1987 and approved for medical use in 2003. It is available in Japan, South Korea and in India. In the US, it received FDA approval in 2009. Kowa Pharmaceuticals, a subsidiary of Kowa Company, is the owner of the American patent to pitavastatin. Read full article at Wikipedia Formula C9H12N2O6 Net Charge 0 Average Mass 244.20146 Monoisotopic Mass 244.06954 InChI InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 InChIKey DRTQHJPVMGBUCF-XVFCMESISA-N SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O Metabolite of Species Details Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed Daphnia magna (NCBI:txid35525) See: Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyondTine Vandenbrouck, Oliver A.H. Jones, Nathalie Dom, Julian L. Griffin, Wim De CoenEnvironment International 36 (2010) 254-268 Saccharomyces cerevisiae (NCBI:txid4932) Source: yeast.sf.net See: PubMed Escherichia coli (NCBI:txid562) See: PubMed Homo sapiens (NCBI:txid9606) See: DOI Roles Classification Biological Role(s): human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). drug metabolite fundamental metabolite Any metabolite produced by all living cells. View more via ChEBI Ontology ChEBI Ontology Outgoing uridine (CHEBI:16704) has functional parent uracil (CHEBI:17568) uridine (CHEBI:16704) has role drug metabolite (CHEBI:49103) uridine (CHEBI:16704) has role fundamental metabolite (CHEBI:78675) uridine (CHEBI:16704) has role human metabolite (CHEBI:77746) uridine (CHEBI:16704) is a uridines (CHEBI:27242) Incoming (5'S,6'R)-C-glycyluridine zwitterion (CHEBI:195553) has functional parent uridine (CHEBI:16704) (5'S,6'S)-C-glycyluridine zwitterion (CHEBI:229461) has functional parent uridine (CHEBI:16704) 3'-(enolpyruvyl)uridine 5'-monophosphate (CHEBI:133864) has functional parent uridine (CHEBI:16704) 5'-O-(dihydroxyphosphanyl)-2'-O-{2-[2-(dimethylamino)ethoxy]ethyl}-5-methyluridine (CHEBI:39913) has functional parent uridine (CHEBI:16704) 5-aminomethyl-2-thiouridine (CHEBI:73768) has functional parent uridine (CHEBI:16704) nikkomycin Z (CHEBI:623918) has functional parent uridine (CHEBI:16704) uridine-5'-carboxamide (CHEBI:195554) has functional parent uridine (CHEBI:16704) uridine residue (CHEBI:73747) is substituent group from uridine (CHEBI:16704) IUPAC Name uridine Synonyms Sources 1-β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione ChEBI 1-β-D-ribofuranosyluracil HMDB β-Uridine HMDB u ChEBI Urd CBN Uridin ChemIDplus Uridine KEGG COMPOUND URIDINE PDBeChem uridine UniProt Manual Xrefs Databases C00019674 KNApSAcK C00299 KEGG COMPOUND DB02745 DrugBank ECMDB00296 ECMDB HMDB0000296 HMDB URI PDBeChem Uridine Wikipedia URIDINE MetaCyc YMDB00127 YMDB View more database links Registry Numbers Types Sources 397474 Gmelin Registry Number Gmelin 58-96-8 CAS Registry Number ChemIDplus 754904 Reaxys Registry Number Reaxys Citations Last Modified 03 March 2017