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kaempferol |
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CHEBI:28499 |
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A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment. |
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This entity has been manually annotated by the ChEBI Team.
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CHEBI:43598, CHEBI:24944, CHEBI:6100
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ChemicalBook:CB6361837, eMolecules:532358, eMolecules:10169597, eMolecules:5753682, eMolecules:1056735, eMolecules:1989215, Selleckchem:Thioguanine, ZINC000006382803 |
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Molfile
XML
SDF
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more structures >>
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call loadScript javascripts\jsmol\core\package.js call loadScript javascripts\jsmol\core\core.z.js -- required by ClazzNode call loadScript javascripts\jsmol\J\awtjs2d\WebOutputChannel.js
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Tioguanine, also known as thioguanine or 6-thioguanine (6-TG) or tabloid is a medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myeloid leukemia (CML). Long-term use is not recommended. It is given by mouth.
Common side effects include bone marrow suppression, liver problems and inflammation of the mouth. It is recommended that liver enzymes be checked weekly when on the medication. People with a genetic deficiency in thiopurine S-methyltransferase are at higher risk of side effects. Avoiding pregnancy when on the medication is recommended. Tioguanine is in the antimetabolite family of medications. It is a purine analogue of guanine and works by disrupting DNA and RNA.
Tioguanine was developed between 1949 and 1951. It is on the World Health Organization's List of Essential Medicines. |
Read full article at Wikipedia
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InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H |
IYRMWMYZSQPJKC-UHFFFAOYSA-N |
Oc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O |
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Pittocaulon velatum
(IPNI:238587-1)
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Found in
stem
(BTO:0001300).
Methanol extract of dried and ground stems and roots
See:
PubMed
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Pittocaulon velatum
(IPNI:238587-1)
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Found in
root
(BTO:0001188).
Methanol extract of dried and ground stems and roots
See:
PubMed
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Ficus mucuso
(NCBI:txid309328)
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Found in
fruit
(BTO:0000486).
Methanolic extract of air-dried and powdered figs(fruits)
See:
PubMed
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Homo sapiens
(NCBI:txid9606)
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Found in
urine
(BTO:0001419).
See:
PubMed
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Homo sapiens
(NCBI:txid9606)
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Found in
blood
(UBERON:0000178).
See:
PubMed
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antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
human urinary metabolite
Any metabolite (endogenous or exogenous) found in human urine samples.
human blood serum metabolite
Any metabolite (endogenous or exogenous) found in human blood serum samples.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
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geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
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View more via ChEBI Ontology
3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
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3,4',5,7-Tetrahydroxyflavone
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KEGG COMPOUND
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4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-5,7,4'-Trihydroxyflavonol
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KEGG COMPOUND
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5,7,4'-trihydroxyflavonol
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ChemIDplus
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C.I. 75640
|
KEGG COMPOUND
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campherol
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ChemIDplus
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Indigo yellow
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KEGG COMPOUND
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Kaempferol
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KEGG COMPOUND
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Kaempherol
|
KEGG COMPOUND
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Kämpferol
|
ChEBI
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Kampherol
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HMDB
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Kempferol
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KEGG COMPOUND
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Nimbecetin
|
KEGG COMPOUND
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Pelargidenolon
|
KEGG COMPOUND
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Populnetin
|
KEGG COMPOUND
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Rhamnolutein
|
KEGG COMPOUND
|
Rhamnolutin
|
KEGG COMPOUND
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Robigenin
|
KEGG COMPOUND
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Swartziol
|
KEGG COMPOUND
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Trifolitin
|
KEGG COMPOUND
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304401
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Reaxys Registry Number
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Reaxys
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520-18-3
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CAS Registry Number
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KEGG COMPOUND
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520-18-3
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CAS Registry Number
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ChemIDplus
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12592675
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PubMed citation
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Europe PMC
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15234754
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PubMed citation
|
Europe PMC
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17426744
|
PubMed citation
|
Europe PMC
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17551714
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PubMed citation
|
Europe PMC
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28166217
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PubMed citation
|
Europe PMC
|
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