CHEBI:30347 - ethylenediamine

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ChEBI Name ethylenediamine ChEBI ID CHEBI:30347 Definition An alkane-α,ω-diamine in which the alkane is ethane. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information ChemicalBook:CB8120056, eMolecules:876432, Selleckchem:Gefitinib, ZINC000019632614 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Gefitinib, sold under the brand name Iressa, is a medication used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR, but resistances to gefitinib can arise through other mutations. It is marketed by AstraZeneca and Teva. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. Read full article at Wikipedia Formula C2H8N2 Net Charge 0 Average Mass 60.09840 Monoisotopic Mass 60.06875 InChI InChI=1S/C2H8N2/c3-1-2-4/h1-4H2 InChIKey PIICEJLVQHRZGT-UHFFFAOYSA-N SMILES NCCN Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): GABA agonist A drug that binds to and activates gamma-aminobutyric acid receptors. Application(s): GABA agonist A drug that binds to and activates gamma-aminobutyric acid receptors. View more via ChEBI Ontology ChEBI Ontology Outgoing ethylenediamine (CHEBI:30347) has parent hydride ethane (CHEBI:42266) ethylenediamine (CHEBI:30347) has role GABA agonist (CHEBI:51373) ethylenediamine (CHEBI:30347) is a alkane-α,ω-diamine (CHEBI:35411) Incoming N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (CHEBI:88217) has functional parent ethylenediamine (CHEBI:30347) ethylenebis(dithiocarbamic acid) (CHEBI:83986) has functional parent ethylenediamine (CHEBI:30347) ethylenediamine derivative (CHEBI:31577) has functional parent ethylenediamine (CHEBI:30347) ethylenediamine dihydrochloride (CHEBI:53626) has functional parent ethylenediamine (CHEBI:30347) aminophylline (CHEBI:2659) has part ethylenediamine (CHEBI:30347) IUPAC Name ethane-1,2-diamine Synonyms Sources 1,2-ethanediamine IUPAC en IUPAC ethylenediamine IUPAC Manual Xrefs Databases CPD-3682 MetaCyc D01114 KEGG DRUG EDN PDBeChem Ethylenediamine Wikipedia HMDB0031225 HMDB View more database links Registry Numbers Types Sources 107-15-3 CAS Registry Number ChemIDplus 107-15-3 CAS Registry Number NIST Chemistry WebBook 1098 Gmelin Registry Number Gmelin 605263 Reaxys Registry Number Reaxys Citations Last Modified 16 February 2016