CHEBI:35255 - chloroform

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ChEBI Name chloroform
ChEBI ID CHEBI:35255
Definition A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:34628, CHEBI:23143
Supplier Information eMolecules:499362, eMolecules:26757802, ZINC000003861782
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Tolbutamide is a first-generation potassium channel blocker, sulfonylurea oral hypoglycemic medication. This drug may be used in the management of type 2 diabetes if diet alone is not effective. Tolbutamide stimulates the secretion of insulin by the pancreas. It is not routinely used due to a higher incidence of adverse effects compared to newer, second-generation sulfonylureas, such as Glibenclamide. It generally has a short duration of action due to its rapid metabolism, so is safe for use in older people. It was discovered in 1956.
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Formula CHCl3
Net Charge 0
Average Mass 119.37674
Monoisotopic Mass 117.91438
InChI InChI=1S/CHCl3/c2-1(3)4/h1H
InChIKey HEDRZPFGACZZDS-UHFFFAOYSA-N
SMILES [H]C(Cl)(Cl)Cl
Roles Classification
Chemical Role(s): non-polar solvent

Biological Role(s): carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
Application(s): refrigerant
A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
central nervous system drug
A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
non-polar solvent

inhalation anaesthetic

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ChEBI Ontology
Outgoing chloroform (CHEBI:35255) has role carcinogenic agent (CHEBI:50903)
chloroform (CHEBI:35255) has role central nervous system drug (CHEBI:35470)
chloroform (CHEBI:35255) has role inhalation anaesthetic (CHEBI:38870)
chloroform (CHEBI:35255) has role non-polar solvent (CHEBI:48355)
chloroform (CHEBI:35255) has role refrigerant (CHEBI:78433)
chloroform (CHEBI:35255) is a chloromethanes (CHEBI:23148)
chloroform (CHEBI:35255) is a one-carbon compound (CHEBI:64708)
Incoming trichloromethyl group (CHEBI:30736) is substituent group from chloroform (CHEBI:35255)
IUPAC Name
chloroform
Synonyms Sources
1,1,1-trichloromethane ChemIDplus
CHCl3 IUPAC
Chloroform KEGG COMPOUND
chloroforme ChemIDplus
chloroformium pro narcosi ChEBI
Trichlormethan NIST Chemistry WebBook
trichloromethane NIST Chemistry WebBook
trichlorométhane ChEBI
Manual Xrefs Databases
4363 DrugCentral
c0595 UM-BBD
C13827 KEGG COMPOUND
Chloroform Wikipedia
CPD-843 MetaCyc
HMDB0029596 HMDB
LSM-37229 LINCS
MCH PDBeChem
View more database links
Registry Numbers Types Sources
1731042 Reaxys Registry Number Reaxys
1837 Gmelin Registry Number Gmelin
67-66-3 CAS Registry Number NIST Chemistry WebBook
67-66-3 CAS Registry Number ChemIDplus
Citations
Last Modified
22 February 2017