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> Main
CHEBI:3750 - clofibrate
Main
ChEBI Ontology
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ChEBI Name
clofibrate
ChEBI ID
CHEBI:3750
Definition
The ethyl ester of clofibric acid.
Stars
This entity has been manually annotated by the ChEBI Team.
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Wikipedia
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Read full article at Wikipedia
Formula
C12H15ClO3
Net Charge
0
Average Mass
242.69900
Monoisotopic Mass
242.07097
InChI
InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3
InChIKey
KNHUKKLJHYUCFP-UHFFFAOYSA-N
SMILES
CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1
Roles Classification
Biological Role
(s):
PPARalpha agonist
A PPAR modulator which activates the peroxisome proliferator-activated receptor-
alpha
.
Application
(s):
anticholesteremic drug
A substance used to lower plasma cholesterol levels.
antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
clofibrate (
CHEBI:3750
)
has functional parent
clofibric acid (
CHEBI:34648
)
clofibrate (
CHEBI:3750
)
has role
anticholesteremic drug (
CHEBI:35821
)
clofibrate (
CHEBI:3750
)
has role
antilipemic drug (
CHEBI:35679
)
clofibrate (
CHEBI:3750
)
has role
geroprotector (
CHEBI:176497
)
clofibrate (
CHEBI:3750
)
has role
PPARα agonist (
CHEBI:70782
)
clofibrate (
CHEBI:3750
)
is a
aromatic ether (
CHEBI:35618
)
clofibrate (
CHEBI:3750
)
is a
ethyl ester (
CHEBI:23990
)
clofibrate (
CHEBI:3750
)
is a
monochlorobenzenes (
CHEBI:83403
)
IUPAC Name
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
INNs
Sources
clofibrate
ChemIDplus
clofibrato
ChemIDplus
clofibratum
ChemIDplus
Synonyms
Sources
2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester
ChemIDplus
2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester
ChemIDplus
alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester
ChemIDplus
alpha-p-Chlorophenoxyisobutyryl ethyl ester
ChemIDplus
Clofibrate
KEGG COMPOUND
EPIB
DrugBank
Ethyl 2-(p-chlorophenoxy)isobutyrate
ChemIDplus
Ethyl chlorophenoxyisobutyrate
ChemIDplus
Ethyl clofibrate
ChemIDplus
Liprin
ChemIDplus
Brand Names
Sources
Atromid-S
KEGG DRUG
ELPI
DrugBank
Lipofacton
DrugBank
Manual Xrefs
Databases
2694
ChemSpider
694
DrugCentral
C06916
KEGG COMPOUND
Clofibrate
Wikipedia
D00279
KEGG DRUG
DB00636
DrugBank
GB860303
Patent
HMDB0014774
HMDB
LSM-2996
LINCS
US3262850
Patent
View more database links
Registry Numbers
Types
Sources
1913459
Beilstein Registry Number
Beilstein
637-07-0
CAS Registry Number
ChemIDplus
637-07-0
CAS Registry Number
NIST Chemistry WebBook
Citations
Types
Sources
23603800
PubMed citation
Europe PMC
26949064
PubMed citation
Europe PMC
27354598
PubMed citation
Europe PMC
28248971
PubMed citation
Europe PMC
28485676
PubMed citation
Europe PMC
28512725
PubMed citation
Europe PMC
28779283
PubMed citation
Europe PMC
29059162
PubMed citation
Europe PMC
30642049
PubMed citation
Europe PMC
33070841
PubMed citation
Europe PMC
33893992
PubMed citation
Europe PMC
PMC7258001
PubMed Central citation
Europe PMC
PMC8265473
PubMed Central citation
Europe PMC
Last Modified
20 September 2021