CHEBI:37510 - anthralin

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name anthralin ChEBI ID CHEBI:37510 Definition An anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information ZINC000535385354 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Hydralazine, sold under the brand name Apresoline among others, is a medication used to treat high blood pressure and heart failure. This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms. It has been found to be particularly useful in heart failure, together with isosorbide dinitrate, for treatment of people of African descent. It is given by mouth or by injection into a vein. Effects usually begin around 15 minutes and last up to six hours. Common side effects include headache and fast heart rate. It is not recommended in people with coronary artery disease or in those with rheumatic heart disease that affects the mitral valve. In those with kidney disease a low dose is recommended. Hydralazine is in the vasodilator family of medications, so it is believed to work by causing the dilation of blood vessels. Hydralazine was discovered while scientists at Ciba were looking for a treatment for malaria. It was patented in 1949. It is on the World Health Organization's List of Essential Medicines. In 2022, it was the 121st most commonly prescribed medication in the United States, with more than 5 million prescriptions. Read full article at Wikipedia Formula C14H10O3 Net Charge 0 Average Mass 226.22740 Monoisotopic Mass 226.06299 InChI InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2 InChIKey NUZWLKWWNNJHPT-UHFFFAOYSA-N SMILES Oc1cccc2Cc3cccc(O)c3C(=O)c12 Roles Classification Application(s): antipsoriatic A drug used to treat psoriasis. View more via ChEBI Ontology ChEBI Ontology Outgoing anthralin (CHEBI:37510) has functional parent anthrone (CHEBI:33835) anthralin (CHEBI:37510) has role antipsoriatic (CHEBI:50748) anthralin (CHEBI:37510) is a anthracenes (CHEBI:46955) anthralin (CHEBI:37510) is tautomer of anthracene-1,8,9-triol (CHEBI:2756) Incoming chrysophanol-9-anthrone (CHEBI:3686) has functional parent anthralin (CHEBI:37510) anthracene-1,8,9-triol (CHEBI:2756) is tautomer of anthralin (CHEBI:37510) IUPAC Name 1,8-dihydroxyanthracen-9(10H)-one Synonyms Sources 1,8-dihydroxy-9(10H)-anthracenone NIST Chemistry WebBook 1,8-dihydroxy-9-anthrone NIST Chemistry WebBook 1,8-dihydroxyanthrone ChemIDplus Anthralin KEGG COMPOUND dithranol ChemIDplus Manual Xrefs Databases 226 DrugCentral C06831 KEGG COMPOUND D00233 KEGG DRUG Dithranol Wikipedia LSM-6530 LINCS View more database links Registry Numbers Types Sources 1143-38-0 CAS Registry Number NIST Chemistry WebBook 1143-38-0 CAS Registry Number ChemIDplus 2054360 Reaxys Registry Number Reaxys Citations Last Modified 22 February 2017