CHEBI:37598 - nitrogen mustard

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ChEBI Name nitrogen mustard
ChEBI ID CHEBI:37598
Definition Compounds having two β-haloalkyl groups bound to a nitrogen atom, as in (X‒CH2‒CH2)2NR.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
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ChEBI Ontology
Outgoing nitrogen mustard (CHEBI:37598) has role alkylating agent (CHEBI:22333)
nitrogen mustard (CHEBI:37598) is a organonitrogen compound (CHEBI:35352)
Incoming 2-({4-[bis(2-chloroethyl)amino]-2-methylphenyl}diazenyl)benzoic acid (CHEBI:34193) is a nitrogen mustard (CHEBI:37598)
3,4-dibromopyrrole-2,5-dione (CHEBI:210335) is a nitrogen mustard (CHEBI:37598)
3,4-Dichloro-5-hydroxy-2H-pyrrol-2-one (CHEBI:184738) is a nitrogen mustard (CHEBI:37598)
4-hydroperoxycyclophosphamide (CHEBI:196991) is a nitrogen mustard (CHEBI:37598)
4-hydroxycyclophosphamide (CHEBI:1864) is a nitrogen mustard (CHEBI:37598)
4-Ketocyclophosphamide (CHEBI:1887) is a nitrogen mustard (CHEBI:37598)
5-[bis(2-chloroethyl)amino]uracil (CHEBI:9884) is a nitrogen mustard (CHEBI:37598)
Alcophosphamide (CHEBI:80559) is a nitrogen mustard (CHEBI:37598)
Aldophosphamide (CHEBI:2560) is a nitrogen mustard (CHEBI:37598)
bis(2-chloroethyl)amine (CHEBI:37599) is a nitrogen mustard (CHEBI:37598)
Carboxyphosphamide (CHEBI:3410) is a nitrogen mustard (CHEBI:37598)
chlorambucil (CHEBI:28830) is a nitrogen mustard (CHEBI:37598)
cyclophosphamide (CHEBI:4027) is a nitrogen mustard (CHEBI:37598)
ifosfamides (CHEBI:55369) is a nitrogen mustard (CHEBI:37598)
mechlorethamine (CHEBI:28925) is a nitrogen mustard (CHEBI:37598)
melphalan (CHEBI:28876) is a nitrogen mustard (CHEBI:37598)
N-[[4-[bis(2-chloroethyl)amino]-2-methylphenyl]methylideneamino]-2-furancarboxamide (CHEBI:116496) is a nitrogen mustard (CHEBI:37598)
Nitrogen mustard N-oxide (CHEBI:82354) is a nitrogen mustard (CHEBI:37598)
Nitrogen mustard N-oxide hydrochloride (CHEBI:31913) is a nitrogen mustard (CHEBI:37598)
perfosfamide (CHEBI:135223) is a nitrogen mustard (CHEBI:37598)
phosphoramide mustard (CHEBI:8163) is a nitrogen mustard (CHEBI:37598)
quinacrine mustard (CHEBI:37595) is a nitrogen mustard (CHEBI:37598)
IUPAC Name
nitrogen mustards
Synonyms Sources
nitrogen mustard compound ChEBI
nitrogen mustard compounds ChEBI
nitrogen mustards ChEBI
Manual Xref Database
Nitrogen_mustard Wikipedia
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Last Modified
13 June 2014