Amoxicillin is an antibiotic medication belonging to the aminopenicillin class of the penicillin family. The drug is used to treat bacterial infections such as middle ear infection, strep throat, pneumonia, skin infections, odontogenic infections, and urinary tract infections. It is taken orally (swallowed by mouth), or less commonly by either intramuscular injection or by an IV bolus injection, which is a relatively quick intravenous injection lasting from a couple of seconds to a few minutes.
Common adverse effects include nausea and rash. It may also increase the risk of yeast infections and, when used in combination with clavulanic acid, diarrhea. It should not be used in those who are allergic to penicillin. While usable in those with kidney problems, the dose may need to be decreased. Its use in pregnancy and breastfeeding does not appear to be harmful. Amoxicillin is in the β-lactam family of antibiotics.
Amoxicillin was discovered in 1958 and came into medical use in 1972. Amoxil was approved for medical use in the United States in 1974, and in the United Kingdom in 1977. It is on the World Health Organization's List of Essential Medicines. It is one of the most commonly prescribed antibiotics in children. Amoxicillin is available as a generic medication. In 2022, it was the 26th most commonly prescribed medication in the United States, with more than 20 million prescriptions. |
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InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3 |
BTFHLQRNAMSNLC-UHFFFAOYSA-N |
CN(CCCOc1ccc(Cl)cc1Cl)CC#C |
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Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
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EC 1.4.3.4 (monoamine oxidase) inhibitor
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
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antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
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View more via ChEBI Ontology
N-[3-(2,4-dichlorophenoxy)propyl]-N-methylprop-2-yn-1-amine
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clorgilina
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ChemIDplus
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clorgiline
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ChemIDplus
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clorgiline
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WHO MedNet
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clorgilinum
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ChemIDplus
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M & B 9302
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ChemIDplus
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M and B 9302
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ChemIDplus
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M&B 9302
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ChemIDplus
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N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-2-propynylamine
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ChemIDplus
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N-methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine
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ChEBI
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C11685
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KEGG COMPOUND
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Clorgiline
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Wikipedia
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CPD-7656
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MetaCyc
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D03248
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KEGG DRUG
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DB04017
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DrugBank
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LSM-5808
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LINCS
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MLG
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PDBeChem
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View more database links |
17780-72-2
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CAS Registry Number
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ChemIDplus
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17780-72-2
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CAS Registry Number
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NIST Chemistry WebBook
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1976758
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Reaxys Registry Number
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Reaxys
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