CHEBI:39285 - chloropicrin

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ChEBI Name chloropicrin
ChEBI ID CHEBI:39285
Definition A C-nitro compound that is nitromethane in which all three hydrogens are replaced by chlorines. It is a severe irritant, and can cause immediate, severe inflammation of the eyes, nose and throat, and significant injuries to the upper and lower respiratory tract. Formerly stockpiled as a chemical warfare agent, it has been widely used in the US as a soil fumigant, particularly for strawberry crops. It is not approved for use within the European Union.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB1384824, eMolecules:502037, ZINC000001600920
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β-Endorphin (beta-endorphin) is an endogenous opioid neuropeptide and peptide hormone that is produced in certain neurons within the central nervous system and peripheral nervous system. It is one of three endorphins that are produced in humans, the others being α-endorphin and γ-endorphin. There are multiple forms of β-endorphins with the full sequence of Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu (31 amino acids) denoted as β-endorphin(1-31) and variants truncated to the first 26 and 27 amino acids as β-endorphin(1-26) and β-endorphin(1-27). However, β-endorphin(1-31) is the only form that possess a potent analgesic effect and it is the primary form located in the anterior pituitary gland, and regions such as the hypothalamus, midbrain, and amygdala. The first 16 amino acids are identical to α-endorphin. β-Endorphin is considered to be a part of the endogenous opioid and endorphin classes of neuropeptides; all of the established endogenous opioid peptides contain the same N-terminal amino acid sequence, Tyr-Gly-Gly-Phe, followed by either -Met or -Leu. Function of β-endorphin has been known to be associated with hunger, thrill, pain, maternal care, sexual behavior, and reward cognition. In the broadest sense, β-endorphin is primarily utilized in the body to reduce stress and maintain homeostasis. In behavioral research, studies have shown that β-endorphin is released via volume transmission into the ventricular system in response to a variety of stimuli, and novel stimuli in particular.
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Formula CCl3NO2
Net Charge 0
Average Mass 164.37500
Monoisotopic Mass 162.89946
InChI InChI=1S/CCl3NO2/c2-1(3,4)5(6)7
InChIKey LFHISGNCFUNFFM-UHFFFAOYSA-N
SMILES [O-][N+](=O)C(Cl)(Cl)Cl
Roles Classification
Biological Role(s): antifungal agrochemical
Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
Application(s): nematicide
A substance used to destroy pests of the phylum Nematoda (roundworms).
antifungal agrochemical
Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
fumigant insecticide

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ChEBI Ontology
Outgoing chloropicrin (CHEBI:39285) has role antifungal agrochemical (CHEBI:86328)
chloropicrin (CHEBI:39285) has role fumigant insecticide (CHEBI:39277)
chloropicrin (CHEBI:39285) has role nematicide (CHEBI:25491)
chloropicrin (CHEBI:39285) is a C-nitro compound (CHEBI:35716)
chloropicrin (CHEBI:39285) is a one-carbon compound (CHEBI:64708)
chloropicrin (CHEBI:39285) is a organochlorine compound (CHEBI:36683)
IUPAC Name
trichloro(nitro)methane
Synonyms Sources
1,1,1-trichloronitromethane NIST Chemistry WebBook
CCl3NO2 ChEBI
chloropicrin ChemIDplus
Chlorpikrin ChemIDplus
Cl3CNO2 ChEBI
Trichlornitromethan NIST Chemistry WebBook
trichloronitromethane NIST Chemistry WebBook
Manual Xrefs Databases
148 PPDB
C18445 KEGG COMPOUND
chloropicrin Alan Wood's Pesticides
Chloropicrin Wikipedia
View more database links
Registry Numbers Types Sources
1756135 Reaxys Registry Number Reaxys
240197 Gmelin Registry Number Gmelin
76-06-2 CAS Registry Number NIST Chemistry WebBook
76-06-2 CAS Registry Number ChemIDplus
Citations Types Sources
18207489 PubMed citation Europe PMC
19287772 PubMed citation Europe PMC
22516760 PubMed citation Europe PMC
23958081 PubMed citation Europe PMC
24475954 PubMed citation Europe PMC
24548678 PubMed citation Europe PMC
24618853 PubMed citation Europe PMC
25279758 PubMed citation Europe PMC
25531174 PubMed citation Europe PMC
2920227 PubMed citation Europe PMC
3605008 PubMed citation Europe PMC
Last Modified
06 July 2015