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call loadScript javascripts\jsmol\core\package.js call loadScript javascripts\jsmol\core\core.z.js -- required by ClazzNode call loadScript javascripts\jsmol\J\awtjs2d\WebOutputChannel.js
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InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1 |
FBOZXECLQNJBKD-ZDUSSCGKSA-N |
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O |
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Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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EC 1.5.1.3 (dihydrofolate reductase) inhibitor
An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
DNA synthesis inhibitor
Any substance that inhibits the synthesis of DNA.
antimetabolite
A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
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immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
abortifacient
A chemical substance that interrupts pregnancy after implantation.
dermatologic drug
A drug used to treat or prevent skin disorders or for the routine care of skin.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
antirheumatic drug
A drug used to treat rheumatoid arthritis.
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View more via ChEBI Ontology
N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid
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methotrexate
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KEGG DRUG
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methotrexatum
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ChemIDplus
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metotrexato
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ChemIDplus
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4-amino-10-methylfolic acid
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ChemIDplus
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4-amino-N10-methylpteroylglutamic acid
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NIST Chemistry WebBook
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Methotrexate
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KEGG COMPOUND
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METHOTREXATE
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PDBeChem
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MTX
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ChemIDplus
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N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
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NIST Chemistry WebBook
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Emtexate
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DrugBank
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Ledertrexate
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DrugBank
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Rheumatrex
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DrugBank
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Trexall
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DrugBank
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1751
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DrugCentral
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C01937
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KEGG COMPOUND
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D00142
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KEGG DRUG
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DB00563
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DrugBank
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LSM-5690
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LINCS
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Methotrexate
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Wikipedia
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MTX
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PDBeChem
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US2512572
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Patent
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View more database links |
59-05-2
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CAS Registry Number
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NIST Chemistry WebBook
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59-05-2
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CAS Registry Number
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ChemIDplus
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70669
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Beilstein Registry Number
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Beilstein
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