CHEBI:44485 - N-ethylmaleimide

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ChEBI Name N-ethylmaleimide
ChEBI ID CHEBI:44485
ChEBI ASCII Name N-ethylmaleimide
Definition A member of the class of maleimides that is the N-ethyl derivative of maleimide.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:44483, CHEBI:7269
Supplier Information ChemicalBook:CB5748314, eMolecules:475873, ZINC000000901367
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Formulae C6H7NO2
C6H7NO2
Net Charge 0
Average Mass 125.12530
Monoisotopic Mass 125.04768
InChI InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChIKey HDFGOPSGAURCEO-UHFFFAOYSA-N
SMILES CCN1C(=O)C=CC1=O
Roles Classification
Biological Role(s): EC 2.7.1.1 (hexokinase) inhibitor
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate.
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of acyl-CoA dehydrogenase (NADP+), EC 1.3.1.8.
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122).
anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
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ChEBI Ontology
Outgoing N-ethylmaleimide (CHEBI:44485) has functional parent maleimide (CHEBI:16072)
N-ethylmaleimide (CHEBI:44485) has role anticoronaviral agent (CHEBI:149553)
N-ethylmaleimide (CHEBI:44485) has role EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP+)] inhibitor (CHEBI:78377)
N-ethylmaleimide (CHEBI:44485) has role EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor (CHEBI:77115)
N-ethylmaleimide (CHEBI:44485) has role EC 2.7.1.1 (hexokinase) inhibitor (CHEBI:78366)
N-ethylmaleimide (CHEBI:44485) is a maleimides (CHEBI:55417)
IUPAC Name
1-ethyl-1H-pyrrole-2,5-dione
Synonyms Sources
Ethylmaleimide ChemIDplus
N-Ethylmaleimide KEGG COMPOUND
N-ETHYLMALEIMIDE PDBeChem
N-ethylmaleimide UniProt
NEM NIST Chemistry WebBook
Manual Xrefs Databases
C02441 KEGG COMPOUND
DB02967 DrugBank
LSM-4219 LINCS
N-Ethylmaleimide Wikipedia
N-ETHYLMALEIMIDE MetaCyc
NEQ PDBeChem
View more database links
Registry Numbers Types Sources
112448 Beilstein Registry Number Beilstein
112448 Reaxys Registry Number Reaxys
128-53-0 CAS Registry Number NIST Chemistry WebBook
128-53-0 CAS Registry Number ChemIDplus
405614 Gmelin Registry Number Gmelin
Citations Waiting for Citations
Last Modified
23 April 2020