CHEBI:4667 - valproate semisodium

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ChEBI Name valproate semisodium
ChEBI ID CHEBI:4667
Definition A mixture of valproic acid and its sodium salt in a 1:1 molar ratio. It is used for the management and treatment of seizure disorders, mania, and prophylactic treatment of migraine headache.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB4149527, eMolecules:32278126, Selleckchem:Divalproex-sodium
Download Molfile XML SDF
Formula C16H31NaO4
Net Charge 0
Average Mass 310.40470
Monoisotopic Mass 310.21200
InChI InChI=1S/2C8H16O2.Na/c2*1-3-5-7(6-4-2)8(9)10;/h2*7H,3-6H2,1-2H3,(H,9,10);/q;;+1/p-1
InChIKey MSRILKIQRXUYCT-UHFFFAOYSA-M
SMILES [Na+].CCCC(CCC)C(O)=O.CCCC(CCC)C([O-])=O
Roles Classification
Biological Role(s): GABA agent
A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems.
Application(s): antimanic drug
Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders.
anticonvulsant
A drug used to prevent seizures or reduce their severity.
GABA agent
A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing valproate semisodium (CHEBI:4667) has part sodium valproate (CHEBI:9925)
valproate semisodium (CHEBI:4667) has part valproic acid (CHEBI:39867)
valproate semisodium (CHEBI:4667) has role anticonvulsant (CHEBI:35623)
valproate semisodium (CHEBI:4667) has role antimanic drug (CHEBI:35477)
valproate semisodium (CHEBI:4667) has role GABA agent (CHEBI:51374)
valproate semisodium (CHEBI:4667) is a organic sodium salt (CHEBI:38700)
IUPAC Name
sodium 2-propylpentanoate—2-propylpentanoic acid (1:1)
INNs Sources
valproate semisodique ChemIDplus
valproate semisodium ChEBI
valproato semisodico ChemIDplus
valproatum seminatricum ChemIDplus
Synonyms Sources
divalproex sodium ChemIDplus
semisodium valproate ChEBI
sodium divalproate ChemIDplus
sodium hydrogen bis(2-propylpentanoate) ChemIDplus
sodium hydrogen bis(2-propylvalerate) ChemIDplus
sodium hydrogen divalproate ChemIDplus
Manual Xrefs Databases
D00304 KEGG DRUG
DB00510 DrugBank
View more database links
Registry Numbers Types Sources
76584-70-8 CAS Registry Number ChemIDplus
76584-70-8 CAS Registry Number KEGG DRUG
8462424 Beilstein Registry Number Beilstein
Last Modified
20 July 2010