| Levonorgestrel is a hormonal medication which is used in a number of birth control methods. It is combined with an estrogen to make combination birth control pills. As an emergency birth control, sold under the brand names Plan B One-Step and Julie, among others, it is useful within 72 hours of unprotected sex. The more time that has passed since sex, the less effective the medication becomes, and it does not work after pregnancy (implantation) has occurred. Levonorgestrel works by preventing ovulation or fertilization from occurring. It decreases the chances of pregnancy by 57–93%. In an intrauterine device (IUD), such as Mirena among others, it is effective for the long-term prevention of pregnancy. A levonorgestrel-releasing implant is also available in some countries.
Common side effects include nausea, breast tenderness, headaches, and increased, decreased, or irregular menstrual bleeding. When used as an emergency contraceptive, if pregnancy occurs, there is no evidence that its use harms the fetus. It is safe to use during breastfeeding. Birth control that contains levonorgestrel will not change the risk of sexually transmitted infections. It is a progestin and has effects similar to those of the hormone progesterone. It works primarily by preventing ovulation and closing off the cervix to prevent the passage of sperm.
Levonorgestrel was patented in 1960 and introduced for medical use together with ethinylestradiol in 1970. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In the United States, levonorgestrel-containing emergency contraceptives are available over the counter (OTC) for all ages. In 2020, it was the 323rd most commonly prescribed medication in the United States, with more than 800 thousand prescriptions. |
|
Read full article at Wikipedia
|
| InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11) |
| AEOCXXJPGCBFJA-UHFFFAOYSA-N |
|
|
antitubercular agent
A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
fatty acid synthesis inhibitor
Any pathway inhibitor that inhibits the synthesis of fatty acids.
leprostatic drug
A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions.
|
|
|
antitubercular agent
A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
leprostatic drug
A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions.
prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
|
|
View more via ChEBI Ontology
|
2-ethylpyridine-4-carbothioamide
|
ethionamidum
|
ChemIDplus
|
etionamida
|
ChemIDplus
|
|
2-ethyl-4-thiopyridylamide
|
ChEBI
|
|
ETH
|
DrugBank
|
|
Ethinamide
|
DrugBank
|
|
ethionamide
|
UniProt
|
|
Ethionamide
|
KEGG COMPOUND
|
|
Ethioniamide
|
DrugBank
|
|
Ethylisothiamide
|
DrugBank
|
|
Ethyonomide
|
DrugBank
|
|
Etionamid
|
DrugBank
|
|
Etionamide
|
DrugBank
|
|
Etioniamid
|
DrugBank
|
|
ETP
|
DrugBank
|
|
116474
|
Reaxys Registry Number
|
Reaxys
|
|
536-33-4
|
CAS Registry Number
|
KEGG COMPOUND
|
|
536-33-4
|
CAS Registry Number
|
NIST Chemistry WebBook
|
|
536-33-4
|
CAS Registry Number
|
ChemIDplus
|
|
14651620
|
PubMed citation
|
Europe PMC
|
|
15673755
|
PubMed citation
|
Europe PMC
|
|
15850780
|
PubMed citation
|
Europe PMC
|
|
