| Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. It has been used for treatment of giardiasis but is not a preferred agent. It is taken by mouth.
Mebendazole is usually well tolerated. Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy. Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type.
Mebendazole came into use in 1971, after it was developed by Janssen Pharmaceutica in Belgium. It is on the World Health Organization's List of Essential Medicines. Mebendazole is available as a generic medication. |
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InChI=1S/C16H13N3O3/c1- 22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21) |
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tubulin modulator
Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
microtubule-destabilising agent
Any substance that interacts with tubulin to inhibit polymerisation of microtubules.
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antinematodal drug
A substance used in the treatment or control of nematode infestations.
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View more via ChEBI Ontology
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methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate
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(5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester
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ChemIDplus
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MBDZ
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ChemIDplus
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Mebendazole
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KEGG COMPOUND
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Vermox
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ChemIDplus
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31431-39-7
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CAS Registry Number
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ChemIDplus
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759809
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Reaxys Registry Number
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Reaxys
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