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withaferin A |
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CHEBI:69120 |
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A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4β,5β,6β,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity. |
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This entity has been manually annotated by the ChEBI Team.
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CHEBI:10040
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ChemicalBook:CB1285736, eMolecules:32456315, eMolecules:29541168, eMolecules:533157, Selleckchem:Ursodiol(Actigal), ZINC000003914809 |
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Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. In purified form, it has been used to treat or prevent several diseases of the liver or bile ducts.
It is available as a generic medication. |
Read full article at Wikipedia
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InChI=1S/C28H38O6/c1-14-11-21(33-25(32)17(14)13-29)15(2)18-5-6-19-16-12-24-28(34-24)23(31)8-7-22(30)27(28,4)20(16)9-10-26(18,19)3/h7-8,15-16,18-21,23-24,29,31H,5-6,9-13H2,1-4H3/t15-,16-,18+,19-,20-,21+,23-,24+,26+,27-,28+/m0/s1 |
DBRXOUCRJQVYJQ-CKNDUULBSA-N |
C[C@@H]([C@H]1CC[C@H]2[C@@H]3C[C@H]4O[C@]44[C@@H](O)C=CC(=O)[C@]4(C)[C@H]3CC[C@]12C)[C@H]1CC(C)=C(CO)C(=O)O1 |
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Physalis longifolia
(NCBI:txid161495)
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Found in
aerial part
(BTO:0001658).
CH2Cl2-MeOH(1:1) extract of the air-dried aerial parts
See:
PubMed
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apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
(via withanolide )
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antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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View more via ChEBI Ontology
(4β,5β,6β,22R)-4,27-dihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione
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4β,27-dihydroxy-1-oxo-5β,6β-epoxywitha-2,24-dienolide
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ChEBI
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Withaferin A
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KEGG COMPOUND
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5119-48-2
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CAS Registry Number
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KEGG COMPOUND
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5119-48-2
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CAS Registry Number
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ChemIDplus
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6284722
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Reaxys Registry Number
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Reaxys
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