Gliclazide, sold under the brand name Diamicron among others, is a sulfonylurea type of anti-diabetic medication, used to treat type 2 diabetes. It is used when dietary changes, exercise, and weight loss are not enough. It is taken by mouth.
Side effect may include low blood sugar, vomiting, abdominal pain, rash, and liver problems. Use by those with significant kidney problems or liver problems or who are pregnant is not recommended. Gliclazide is in the sulfonylurea family of medications. It works mostly by increasing the release of insulin.
Gliclazide was patented in 1966 and approved for medical use in 1972. It is on the World Health Organization's List of Essential Medicines. It is not available for sale in the United States.
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InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3 |
HYIMSNHJOBLJNT-UHFFFAOYSA-N |
COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC |
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Homo sapiens
(NCBI:txid9606)
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See:
DOI
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calcium channel blocker
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
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vasodilator agent
A drug used to cause dilation of the blood vessels.
tocolytic agent
Any compound used to suppress premature labour and immature birth by suppressing uterine contractions.
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View more via ChEBI Ontology
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
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nifedipine
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ChemIDplus
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nifedipino
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ChemIDplus
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nifedipinum
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ChemIDplus
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4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylester
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ChemIDplus
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Nifedipine
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KEGG COMPOUND
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Adalat
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DrugBank
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Adapine
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DrugBank
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Coracten
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DrugBank
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Nifecard
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DrugBank
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Nifecor
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DrugBank
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Nifedipres
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DrugBank
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Procardia
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DrugBank
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1922
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DrugCentral
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C07266
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KEGG COMPOUND
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D00437
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KEGG DRUG
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DB01115
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DrugBank
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LSM-4176
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LINCS
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Nifedipine
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Wikipedia
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View more database links |
21829-25-4
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CAS Registry Number
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KEGG COMPOUND
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21829-25-4
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CAS Registry Number
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NIST Chemistry WebBook
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21829-25-4
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CAS Registry Number
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ChemIDplus
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497773
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Beilstein Registry Number
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Beilstein
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