oxycodone (CHEBI:7852)

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ChEBI Name	oxycodone

ChEBI ID	CHEBI:7852

Definition	A semisynthetic opioid of formula C₁₈H₂₁NO₄ that is derived from thebaine. It is a moderately potent opioid analgesic, generally used for relief of moderate to severe pain.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information	No supplier information found for this compound.

Download	Molfile XML SDF

Wikipedia	License
Caprylic acid (from Latin capra 'goat'), also known under the systematic name octanoic acid or C8 Acid, is a saturated fatty acid, medium-chain fatty acid (MCFA). It has the structural formula H3C−(CH2)6−COOH, and is a colorless oily liquid that is minimally soluble in water with a slightly unpleasant rancid-like smell and taste. Salts and esters of octanoic acid are known as octanoates or caprylates. The name of the related acyl group is octanoyl, capryloyl, or caprylyl. It is a common industrial chemical, which is produced by oxidation of the C8 aldehyde. Its compounds are found naturally in the milk of various mammals and as a minor constituent of coconut oil and palm kernel oil. Two other acids are named after goats via the Latin word capra: caproic acid (C6) and capric acid (C10). Together, these three fatty acids comprise 15% of the fatty acids in goat milk fat.
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Formula

C18H21NO4

Net Charge

Average Mass

315.36360

Monoisotopic Mass

315.14706

InChI

InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1

InChIKey

BRUQQQPBMZOVGD-XFKAJCMBSA-N

SMILES

COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O

Roles Classification
Biological Role(s):	opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. mu-opioid receptor agonist A compound that exhibits agonist activity at the mu-opioid receptor.

Application(s):	opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. mu-opioid receptor agonist A compound that exhibits agonist activity at the mu-opioid receptor. antitussive An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

ChEBI Ontology
Outgoing	oxycodone (CHEBI:7852) has functional parent thebaine (CHEBI:9519) oxycodone (CHEBI:7852) has parent hydride morphinan (CHEBI:35649) oxycodone (CHEBI:7852) has role μ-opioid receptor agonist (CHEBI:55322) oxycodone (CHEBI:7852) has role antitussive (CHEBI:51177) oxycodone (CHEBI:7852) has role opioid analgesic (CHEBI:35482) oxycodone (CHEBI:7852) is a organic heteropentacyclic compound (CHEBI:38164) oxycodone (CHEBI:7852) is a semisynthetic derivative (CHEBI:72588) oxycodone (CHEBI:7852) is conjugate base of oxycodone(1+) (CHEBI:134686)

Incoming	oxycodone(1+) (CHEBI:134686) is conjugate acid of oxycodone (CHEBI:7852)

IUPAC Name

14-hydroxy-3-methoxy-17-methyl-4,5α-epoxymorphinan-6-one

Synonyms	Sources
(-)-14-Hydroxydihydrocodeinone	ChemIDplus
4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one	ChemIDplus
4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one	ChemIDplus
Dihydro-14-hydroxycodeinone	ChemIDplus
Dihydrohydroxycodeinone	ChemIDplus
Dihydroxycodeinone	ChemIDplus
Oxycodone	KEGG COMPOUND

Last Modified

22 February 2017