AmiGO 2: Term Details for "translation" (GO:0006412)

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Term Information

Accession: GO:0006412
Name: translation
Ontology: biological_process
Synonyms: protein anabolism, protein biosynthesis, protein biosynthetic process, protein formation, protein synthesis, protein translation
Alternate IDs: GO:0043037, GO:0006416, GO:0006453
Definition: The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. Source: GOC:go_curators
Comment: None
History: See term history for GO:0006412 at QuickGO
Chem. react.: None
Subset: goslim_metagenomics; goslim_drosophila; goslim_chembl; goslim_plant; goslim_candida; goslim_pir; goslim_euk_cellular_processes_ribbon; goslim_prokaryote; goslim_prokaryote_ribbon
Related: Link to all genes and gene products annotated to translation (excluding "regulates").; Link to all direct and indirect annotations to translation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for translation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0044238 primary metabolic process
GO:0010467 gene expression
GO:0019538 protein metabolic process
GO:0006412 translation
GO:0002181 cytoplasmic translation
GO:1990145 maintenance of translational fidelity
GO:0032543 mitochondrial translation
GO:0017148 negative regulation of translation
GO:0032544 plastid translation
GO:0045727 positive regulation of translation
GO:0006417 regulation of translation
GO:0043143 regulation of translation by machinery localization
GO:0005840 ribosome
GO:0140241 translation at synapse
GO:0008135 translation factor activity, RNA binding
GO:0006414 translational elongation
GO:0006413 translational initiation
GO:0006415 translational termination
GO:0030533 triplet codon-amino acid adaptor activity
GO:0006418 tRNA aminoacylation for protein translation

Parents of translation (GO:0006412)

subject	relation	object
translation	RO:0002224	translational initiation (GO:0006413)
translation	is_a	protein metabolic process (GO:0019538)
translation	is_a	macromolecule biosynthetic process (GO:0009059)
translation	RO:0002162	cellular organisms (NCBITaxon:131567)
translation	RO:0004008	protein (CHEBI:36080)
translation	BFO:0000050	gene expression (GO:0010467)
translation	RO:0002230	translational termination (GO:0006415)
translation	BFO:0000051	translational elongation (GO:0006414)

Children of translation (GO:0006412)

subject	relation	object
triplet codon-amino acid adaptor activity (GO:0030533)	BFO:0000050	translation
tRNA aminoacylation for protein translation (GO:0006418)	BFO:0000050	translation
maintenance of translational fidelity (GO:1990145)	BFO:0000050	translation
mitochondrial translation (GO:0032543)	is_a	translation
negative regulation of translation (GO:0017148)	RO:0002212	translation
translational termination (GO:0006415)	BFO:0000050	translation
translational elongation (GO:0006414)	BFO:0000050	translation
symbiont-mediated suppression of host translation (GO:0039604)	RO:0012014	translation
symbiont-mediated perturbation of host translation (GO:0019057)	RO:0002010	translation
translation at synapse (GO:0140241)	is_a	translation
protein (PR:000000001)	RO:0002353	translation
plastid translation (GO:0032544)	is_a	translation
translation factor activity, RNA binding (GO:0008135)	BFO:0000050	translation
ribosome (GO:0005840)	RO:0002216	translation
regulation of translation by machinery localization (GO:0043143)	BFO:0000050	translation
cytoplasmic translation (GO:0002181)	is_a	translation
translational initiation (GO:0006413)	BFO:0000050	translation
SRP-dependent cotranslational protein targeting to membrane (GO:0006614)	BFO:0000051	translation
positive regulation of translation (GO:0045727)	RO:0002213	translation
regulation of translation (GO:0006417)	RO:0002211	translation

Reactome: R-HSA-72766
Wikipedia: Translation_(genetics)