Term Information

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Accession
GO:0070269
Name
pyroptotic inflammatory response
Ontology
biological_process
Synonyms
pyroptosis
Alternate IDs
None
Definition
A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. Source: PMID:21760595, PMID:18846107, PMID:33883744
Comment
None
History
See term history for GO:0070269 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of pyroptotic inflammatory response (GO:0070269)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pyroptotic inflammatory response [RO:0002162 relation] RO:0002162  Vertebrata (NCBITaxon:7742)
pyroptotic inflammatory response [is_a relation] is_a  inflammatory response (GO:0006954)
Children of pyroptotic inflammatory response (GO:0070269)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of pyroptotic inflammatory response (GO:0160028) [RO:0002212 relation] RO:0002212  pyroptotic inflammatory response
pyroptotic cell death (GO:0141201) [is_a relation] is_a  pyroptotic inflammatory response
positive regulation of pyroptotic inflammatory response (GO:0140639) [RO:0002213 relation] RO:0002213  pyroptotic inflammatory response
None.