U.S. flag

An official website of the United States government

Zfp397 zinc finger protein 397 [ Mus musculus (house mouse) ]

Gene ID: 69256, updated on 9-Dec-2024

Summary

Official Symbol
Zfp397provided by MGI
Official Full Name
zinc finger protein 397provided by MGI
Primary source
MGI:MGI:1916506
See related
Ensembl:ENSMUSG00000024276 AllianceGenome:MGI:1916506
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810411K16Rik; 6720480F11Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including cytosol; microtubule cytoskeleton; and nucleolus. Is expressed in central nervous system; early conceptus; and genitourinary system. Orthologous to human ZNF397 (zinc finger protein 397). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in CNS E11.5 (RPKM 10.6), CNS E14 (RPKM 9.5) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Zfp397 in Genome Data Viewer
Location:
18 A2; 18 12.44 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (24085798..24098030)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (23952741..23964671)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_44048 Neighboring gene zinc finger and SCAN domain containing 30 Neighboring gene predicted gene, 46611 Neighboring gene ribosomal protein L19, pseudogene 7 Neighboring gene STARR-seq mESC enhancer starr_44049 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:24145637-24145876 Neighboring gene STARR-seq mESC enhancer starr_44051 Neighboring gene zinc finger protein 35 Neighboring gene zinc finger protein 24

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytoplasm  
located_in cytosol  
located_in microtubule cytoskeleton  
located_in nucleolus  
located_in nucleus  
located_in plasma membrane  

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027007.2NP_081283.2  zinc finger protein 397

    See identical proteins and their annotated locations for NP_081283.2

    Status: VALIDATED

    Source sequence(s)
    AC126807, AK032001, AY338468
    Consensus CDS
    CCDS29096.1
    UniProtKB/TrEMBL
    Q7TNK4
    Related
    ENSMUSP00000057253.5, ENSMUST00000060762.6
    Conserved Domains (3) summary
    smart00431
    Location:46152
    SCAN; leucine rich region
    COG5048
    Location:264520
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:392412
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    24085798..24098030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246997.4XP_011245299.1  zinc finger protein 397 isoform X1

    See identical proteins and their annotated locations for XP_011245299.1

    UniProtKB/TrEMBL
    Q7TNK4
    Conserved Domains (3) summary
    smart00431
    Location:46152
    SCAN; leucine rich region
    COG5048
    Location:264520
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:392412
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_011246996.3XP_011245298.1  zinc finger protein 397 isoform X1

    See identical proteins and their annotated locations for XP_011245298.1

    UniProtKB/TrEMBL
    Q7TNK4
    Conserved Domains (3) summary
    smart00431
    Location:46152
    SCAN; leucine rich region
    COG5048
    Location:264520
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:392412
    ZF_C2H2; C2H2 Zn finger [structural motif]

External link. Please review our privacy policy.